Patents by Inventor Simon Gessler

Simon Gessler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRYSTALLINE SOLVATES OF 6-(PIPERIDIN-4-YLOXY)-2H-ISOQUINOLIN-1-ONE HYDROCHLORIDE
    Publication number: 20140221656
    Abstract: The present invention relates to crystalline solvates of 6-(Piperidin-4-yloxy)-2H-isoquinolin-1-one hydrochloride, processes for their preparation and the use thereof.
    Type: Application
    Filed: April 4, 2014
    Publication date: August 7, 2014
    Applicant: SANOFI
    Inventors: Norbert Nagel, Bruno Baumgartner, Harald Berchtold, Oliver Plettenburg, Dieter Kadereit, Mandy Mohnicke, Simon Gessler, Joachim Tillner
  • Process for preparing 6-substituted-1-(2H)-isoquinolinones and intermediate compound
    Patent number: 8785642
    Abstract: The present invention relates to novel substituted phenyl compounds of the formula and to a process for making them. The compounds can be used as intermediates for making 6-substituted-1-(2H)-isoquinolinone derivatives.
    Type: Grant
    Filed: June 27, 2012
    Date of Patent: July 22, 2014
    Assignee: Sanofi
    Inventors: Simon Gessler, Theo Wollmann
  • Process for the preparation of 6-substituted-1-(2H)-isoquinolinones
    Patent number: 8716481
    Abstract: The present invention relates to a process for making 6-substituted-1-(2H)-isoquinolinone derivatives of formula (I) wherein R1 and n are as described in the specification. The present invention further relates to novel intermediates which are used in the process according to the invention and to processes for preparing such intermediates.
    Type: Grant
    Filed: June 17, 2010
    Date of Patent: May 6, 2014
    Assignee: Sanofi
    Inventors: Kai Rossen, Hermut Wehlan, Oliver Plettenburg, Volker Kraft, Guenter Billen, Simon Gessler
  • Crystalline solvates of 6-(piperidin-4-yloxy)-2H-isoquinolin-1-one hydrochloride
    Patent number: 8710078
    Abstract: The present invention relates to crystalline solvates of 6-(Piperidin-4-yloxy)-2H-isoquinolin-1-one hydrochloride, processes for their preparation and the use thereof.
    Type: Grant
    Filed: June 27, 2012
    Date of Patent: April 29, 2014
    Assignee: Sanofi
    Inventors: Norbert Nagel, Bruno Baumgartner, Harald Berchtold, Oliver Plettenburg, Dieter Kadereit, Mandy Mohnicke, Simon Gessler, Joachim Tillner
  • Polymorphs of 6-(piperidin-4-yloxy)-2H-isoquinolin-1-one hydrochloride
    Patent number: 8598201
    Abstract: The present invention relates to new crystalline polymorphs of 6-(Piperidin-4-yloxy)-2H-isoquinolin-1-one hydrochloride, processes for their preparation and their use, in particular for the preparation of medicaments.
    Type: Grant
    Filed: June 27, 2012
    Date of Patent: December 3, 2013
    Assignee: Sanofi
    Inventors: Norbert Nagel, Bruno Baumgartner, Harald Berchtold, Oliver Plettenburg, Dieter Kadereit, Mandy Mohnicke, Simon Gessler, Joachim Tillner
  • 3-[4-(PHENYLAMINOOXALYLAMINO)PHENYL]HEX-4-YNOIC ACIDS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS A MEDICAMENT
    Publication number: 20130172248
    Abstract: The invention relates to 3-[4-(phenylaminooxalylamino)phenyl]hex-4-ynoic acids, and to physiologically compatible salts thereof. The invention relates to compounds of the formula I in which R1, R2, R3 and R4 are each defined as specified, and to physiologically compatible salts thereof. The compounds are suitable, for example, for treatment of diabetes.
    Type: Application
    Filed: January 4, 2013
    Publication date: July 4, 2013
    Inventors: Elisabeth DEFOSSA, Viktoria DIETRICH, Thomas KLABUNDE, Stefanie KEIL, Siegfried STENGELIN, Guido HASCHKE, Andreas HERLING, Johanna KUHLMANN-GOTTKE, Stefan BARTOSCHEK, Simon GESSLER, Angela DUDDA, Guenter BILLEN, Thomas OLPP, Joerg RIEKE-ZAPP
  • CRYSTALLINE SOLVATES OF 6-(PIPERIDIN-4-YLOXY)-2H-ISOQUINOLIN-1-ONE HYDROCHLORIDE
    Publication number: 20130012444
    Abstract: The present invention relates to crystalline solvates of 6-(Piperidin-4-yloxy)-2H-isoquinolin-1-one hydrochloride, processes for their preparation and the use thereof.
    Type: Application
    Filed: June 27, 2012
    Publication date: January 10, 2013
    Applicant: SANOFI
    Inventors: Norbert NAGEL, Bruno BAUMGARTNER, Harald BERCHTOLD, Oliver PLETTENBURG, Dieter KADEREIT, Mandy MOHNICKE, Simon GESSLER, Joachim TILLNER
  • POLYMORPHS OF 6-(PIPERIDIN-4-YLOXY)-2H-ISOQUINOLIN-1-ONE HYDROCHLORIDE
    Publication number: 20130012479
    Abstract: The present invention relates to new crystalline polymorphs of 6-(Piperidin-4-yloxy)-2H-isoquinolin-1-one hydrochloride, processes for their preparation and their use, in particular for the preparation of medicaments.
    Type: Application
    Filed: June 27, 2012
    Publication date: January 10, 2013
    Applicant: SANOFI
    Inventors: Norbert NAGEL, Bruno BAUMGARTNER, Harald BERCHTOLD, Oliver PLETTENBURG, Dieter KADEREIT, Mandy MOHNICKE, Simon GESSLER, Joachim TILLNER
  • SUBSTITUTED PHENYL COMPOUNDS
    Publication number: 20130012711
    Abstract: The present invention relates to novel substituted phenyl compounds of the formula and to a process for making them. The compounds can be used as intermediates for making 6-substituted-1-(2H)-isoquinolinone derivatives.
    Type: Application
    Filed: June 27, 2012
    Publication date: January 10, 2013
    Applicant: SANOFI
    Inventors: Simon GESSLER, Theo WOLLMANN
  • Use of a metal complex as an n-Dopant for an organic semiconducting matrix material, organic of semiconducting material and electronic component, and also a dopant and ligand and process for producing same
    Patent number: 8258501
    Abstract: A method of using a metal complex as an n-dopant for doping an organic semiconducting matrix material in order to alter the latter's electrical characteristics is provided. In order to provide n-doped organic semiconductors with matrix materials having a low reduction potential, while achieving high conductivities, the n-dopant is a neutral electron-rich metal complex with a neutral or charged transition metal atom as a central atom and having at least 16 valence electrons. The complex can be polynuclear and can possess at least one metal-metal bond. At least one ligand can form a ? complex with the central atom, which can be a bridge ligand, or it can contain at least one carbanion-carbon atom or a divalent atom. Methods for providing the novel n-dopants are provided.
    Type: Grant
    Filed: March 3, 2005
    Date of Patent: September 4, 2012
    Assignee: Novaled AG
    Inventors: Ansgar Werner, Olaf Kühl, Simon Gessler, Horst Hartmann, Andre Grüssing, Michael Limmert, Andrea Lux, Kentaro Harada
  • PROCESS FOR THE PREPARATION OF 6-SUBSTITUTED-1-(2H)-ISOQUINOLINONES
    Publication number: 20110021779
    Abstract: The present invention relates to a process for making 6-substituted-1-(2H)-isoquinolinone derivatives of formula (I) wherein R1 and n are as described in the specification. The present invention further relates to novel intermediates which are used in the process according to the invention and to processes for preparing such intermediates.
    Type: Application
    Filed: June 17, 2010
    Publication date: January 27, 2011
    Applicant: SANOFI-AVENTIS
    Inventors: Kai ROSSEN, Hermut WEHLAN, Oliver PLETTENBURG, Volker KRAFT, Guenter BILLEN, Simon GESSLER
  • Use of a Metal Complex as an N-Dopant for an Organic Semiconducting Matrix Material, Organic of Semiconducting Material and Electronic Component, and also a Dopant and Ligand and Process for Producing same
    Publication number: 20090212280
    Abstract: A method of using a metal complex as an n-dopant for doping an organic semiconducting matrix material in order to alter the latter's electrical characteristics is provided. In order to provide n-doped organic semiconductors with matrix materials having a low reduction potential, while achieving high conductivities, the n-dopant is a neutral electron-rich metal complex with a neutral or charged transition metal atom as a central atom and having at least 16 valence electrons. The complex can be polynuclear and can possess at least one metal-metal bond. At least one ligand can form a ? complex with the central atom, which can be a bridge ligand, or it can contain at least one carbanion-carbon atom or a divalent atom. Methods for providing the novel n-dopants are provided.
    Type: Application
    Filed: March 3, 2005
    Publication date: August 27, 2009
    Inventors: Ansgar Werner, Olaf Kühl, Simon Gessler, Horst Hartmann, Andre Grüssing, Michael Limmert, Andrea Lux, Kentaro Harada