Patents by Inventor Simon Nguyen
Simon Nguyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240157335Abstract: A stationary phase for high-performance liquid chromatography including monofunctional primary silane functionalized silica provides improved separation performance for the preparative or process scale purification of cannabidiol (CBD) and tetrahydro-cannabinol (THC). Silica bonded with monofunctional primary silane(s) provides more efficient separation of these molecules through higher resolution values, reduced peak broadening and lower separation impedance, thus enabling higher purity product or more efficient purification process.Type: ApplicationFiled: March 9, 2022Publication date: May 16, 2024Applicant: W.R. Grace & Co.-Conn.Inventors: Keling ZHANG, Reno NGUYEN, Simon THOMAS
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Patent number: 11948054Abstract: A system and method for transferring an adversarial attack involving generating a surrogate model having an architecture and a dataset that mirrors at least one aspect of a target model of a target module, wherein the surrogate model includes a plurality of classes. The method involves generating a masked version of the surrogate model having fewer classes than the surrogate model by randomly selecting at least one class of the plurality of classes for removal. The method involves attacking the masked surrogate model to create a perturbed sample. The method involves generalizing the perturbed sample for use with the target module. The method involves transferring the perturbed sample to the target module to alter an operating parameter of the target model.Type: GrantFiled: October 29, 2020Date of Patent: April 2, 2024Assignee: BOOZ ALLEN HAMILTON INC.Inventors: Luke Edward Richards, Andre Tai Nguyen, Ryan Joseph Capps, Edward Simon Paster Raff
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Patent number: 11942395Abstract: An apparatus including first and second substrates. The first and second substrates each include a base and at least one peripheral wall extending from the base. One of the at least one peripheral walls of the first or second substrates includes at least one well, and the other of the at least one peripheral walls of the first or the seconds substrate that does not include a well is mechanically anchored to the well. The apparatus includes a stack having a first and second end, and the stack is disposed on the base of the first and/or the second substrates at the first and/or second ends. The stack includes at least one element configured to generate energy. A method of assembling the apparatus by contacting the substrates.Type: GrantFiled: November 24, 2021Date of Patent: March 26, 2024Assignee: Ciena CorporationInventors: Raphael Beaupré-Laflamme, Simon Savard, Lam Nguyen
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Patent number: 11103261Abstract: An ultrasound catheter includes a catheter body, an ultrasound transmission member, a sonic connector, a constraining member, and a vibrational absorber. The vibrational absorber has an opening through which the ultrasonic transmission member extends. The vibrational absorber is located in a recessed portion of the constraining member. The vibrational absorber is both longitudinally interposed between the constraining member and the distal portion of the sonic connector and laterally interposed between the recessed portion of the constraining member and the ultrasound transmission member. The recessed portion of the constraining member overlaps a portion of an exterior of the distal portion of the sonic connector.Type: GrantFiled: October 17, 2018Date of Patent: August 31, 2021Assignee: C.R. Bard, Inc.Inventors: Henry Nita, Jeff Sarge, Simon Nguyen
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Patent number: 10376272Abstract: An ultrasonic catheter includes a body and an ultrasound transmission member disposed in the body. A head is coupled to the ultrasound transmission member, wherein a gap separates the head from a body distal end. A guidewire tube extends through the body and the head. A proximal end connector assembly includes a hub and an absorber member. The hub has a bore coupled to and in fluid communication with the body. The absorber member is disposed within the bore around the ultrasound transmission member. A sonic connector is disposed between the ultrasound transmission member and a separate generator.Type: GrantFiled: August 28, 2017Date of Patent: August 13, 2019Assignee: FLOWCARDIA, INC.Inventors: Henry Nita, Jeff Sarge, Martinos Tran, Simon Nguyen
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Publication number: 20190059920Abstract: An ultrasound catheter includes a catheter body, an ultrasound transmission member, a sonic connector, a constraining member, and a vibrational absorber. The vibrational absorber has an opening through which the ultrasonic transmission member extends. The vibrational absorber is located in a recessed portion of the constraining member. The vibrational absorber is both longitudinally interposed between the constraining member and the distal portion of the sonic connector and laterally interposed between the recessed portion of the constraining member and the ultrasound transmission member. The recessed portion of the constraining member overlaps a portion of an exterior of the distal portion of the sonic connector.Type: ApplicationFiled: October 17, 2018Publication date: February 28, 2019Inventors: Henry Nita, Jeff Sarge, Simon Nguyen
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Patent number: 10130380Abstract: Ultrasound catheter devices and methods of the present invention generally provide for ablation and/or disruption of vascular occlusions. An ultrasound transmission member, such as a wire, transmits vibrational energy from an ultrasound transducer to a distal head of the catheter to disrupt vascular occlusions. An absorber member is disposed on or around the ultrasound transmission wire at a location adjacent the sonic connector of the catheter. The absorber member absorbs heat, vibrations, and/or the like from the ultrasound transmission wire at or near the area where the transmission wire is coupled with the sonic connector. The absorptive function typically slows the process of wear and tear on the transmission wire, thus extending the useful life of the ultrasound catheter.Type: GrantFiled: February 6, 2015Date of Patent: November 20, 2018Assignee: Flowcardia, Inc.Inventors: Henry Nita, Jeff Sarge, Simon Nguyen
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Publication number: 20170354428Abstract: An ultrasonic catheter includes a body and an ultrasound transmission member disposed in the body. A head is coupled to the ultrasound transmission member, wherein a gap separates the head from a body distal end. A guidewire tube extends through the body and the head. A proximal end connector assembly includes a hub and an absorber member. The hub has a bore coupled to and in fluid communication with the body. The absorber member is disposed within the bore around the ultrasound transmission member. A sonic connector is disposed between the ultrasound transmission member and a separate generator.Type: ApplicationFiled: August 28, 2017Publication date: December 14, 2017Inventors: Henry Nita, Jeff Sarge, Martinos Tran, Simon Nguyen
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Patent number: 9770250Abstract: Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, an ultrasound catheter includes an elongate flexible catheter body with one or more lumens. An ultrasound transmission member or wire extends longitudinally through the catheter body lumen and, in many embodiments, a guide wire tube also extends through the same lumen. A distal head is fixed to or otherwise mechanically coupled with the distal end of the ultrasound transmission member or wire and is positioned adjacent the distal end of the catheter body. Although the distal end of the catheter body overlaps the distal head, the distal head is not directly affixed to the distal end of the catheter body. Thus, the distal tip may move freely, relative to the distal end of the catheter body when ultrasonic energy is applied through the ultrasound transmission member.Type: GrantFiled: April 14, 2016Date of Patent: September 26, 2017Assignee: Flowcardia, Inc.Inventors: Henry Nita, Jeff Sarge, Martinos Tran, Simon Nguyen
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Publication number: 20170265886Abstract: Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and, in some embodiments, a guidewire tube extending through the lumen. A distal head for disrupting occlusions is coupled with the distal end of the ultrasound transmission member and is positioned adjacent the distal end of the catheter body. Some embodiments include improved features such as a bend in the catheter body for enhancing positioning and/or advancement of the catheter.Type: ApplicationFiled: June 5, 2017Publication date: September 21, 2017Inventors: Henry Nita, Jeff Sarge, Simon Nguyen
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Patent number: 9585684Abstract: Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and, in some embodiments, a guidewire tube extending through the lumen. A distal head for disrupting occlusions is coupled with the distal end of the ultrasound transmission member and is positioned adjacent the distal end of the catheter body. Some embodiments include improved features such as a bend in the catheter body for enhancing positioning and/or advancement of the catheter.Type: GrantFiled: August 4, 2014Date of Patent: March 7, 2017Assignee: Flowcardia, Inc.Inventors: Henry Nita, Jeff Sarge, Simon Nguyen
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Publication number: 20160242797Abstract: Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, an ultrasound catheter includes an elongate flexible catheter body with one or more lumens. An ultrasound transmission member or wire extends longitudinally through the catheter body lumen and, in many embodiments, a guide wire tube also extends through the same lumen. A distal head is fixed to or otherwise mechanically coupled with the distal end of the ultrasound transmission member or wire and is positioned adjacent the distal end of the catheter body. Although the distal end of the catheter body overlaps the distal head, the distal head is not directly affixed to the distal end of the catheter body. Thus, the distal tip may move freely, relative to the distal end of the catheter body when ultrasonic energy is applied through the ultrasound transmission member.Type: ApplicationFiled: April 14, 2016Publication date: August 25, 2016Inventors: Henry Nita, Jeff Sarge, Martinos Tran, Simon Nguyen
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Patent number: 9314258Abstract: Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, an ultrasound catheter includes an elongate flexible catheter body with one or more lumens. An ultrasound transmission member or wire extends longitudinally through the catheter body lumen and, in many embodiments, a guide wire tube also extends through the same lumen. A distal head is fixed to or otherwise mechanically coupled with the distal end of the ultrasound transmission member or wire and is positioned adjacent the distal end of the catheter body. Although the distal end of the catheter body overlaps the distal head, the distal head is not directly affixed to the distal end of the catheter body. Thus, the distal tip may move freely, relative to the distal end of the catheter body when ultrasonic energy is applied through the ultrasound transmission member.Type: GrantFiled: April 3, 2014Date of Patent: April 19, 2016Assignee: FLOWCARDIA, INC.Inventors: Henry Nita, Jeff Sarge, Martinos Tran, Simon Nguyen
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Publication number: 20150150571Abstract: Ultrasound catheter devices and methods of the present invention generally provide for ablation and/or disruption of vascular occlusions. An ultrasound transmission member, such as a wire, transmits vibrational energy from an ultrasound transducer to a distal head of the catheter to disrupt vascular occlusions. An absorber member is disposed on or around the ultrasound transmission wire at a location adjacent the sonic connector of the catheter. The absorber member absorbs heat, vibrations, and/or the like from the ultrasound transmission wire at or near the area where the transmission wire is coupled with the sonic connector. The absorptive function typically slows the process of wear and tear on the transmission wire, thus extending the useful life of the ultrasound catheter.Type: ApplicationFiled: February 6, 2015Publication date: June 4, 2015Inventors: Henry Nita, Jeff Sarge, Simon Nguyen
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Patent number: 8961423Abstract: Ultrasound catheter devices and methods of the present invention generally provide for ablation and/or disruption of vascular occlusions. An ultrasound transmission member, such as a wire, transmits vibrational energy from an ultrasound transducer to a distal head of the catheter to disrupt vascular occlusions. An absorber member is disposed on or around the ultrasound transmission wire at a location adjacent the sonic connector of the catheter. The absorber member absorbs heat, vibrations, and/or the like from the ultrasound transmission wire at or near the area where the transmission wire is coupled with the sonic connector. The absorptive function typically slows the process of wear and tear on the transmission wire, thus extending the useful life of the ultrasound catheter.Type: GrantFiled: October 1, 2009Date of Patent: February 24, 2015Assignee: Flowcardia, Inc.Inventors: Henry Nita, Jeff Sarge, Simon Nguyen
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Patent number: 8956375Abstract: Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and a distal head coupled with the transmission member and positioned adjacent the distal end of the catheter body for disrupting occlusions. Improved features of ultrasound catheters include prevention of independent rotation of the ultrasound transmission member, a safety anchor for the distal head, a one-piece transmission member/distal head and the like.Type: GrantFiled: September 23, 2011Date of Patent: February 17, 2015Assignee: Flowcardia, Inc.Inventors: Henry Nita, Jeff Sarge, Simon Nguyen, Richard Spano
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Publication number: 20150025543Abstract: Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and, in some embodiments, a guidewire tube extending through the lumen. A distal head for disrupting occlusions is coupled with the distal end of the ultrasound transmission member and is positioned adjacent the distal end of the catheter body. Some embodiments include improved features such as a bend in the catheter body for enhancing positioning and/or advancement of the catheter.Type: ApplicationFiled: August 4, 2014Publication date: January 22, 2015Inventors: Henry Nita, Jeff Sarge, Simon Nguyen
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Publication number: 20150025544Abstract: Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and, in some embodiments, a guidewire tube extending through the lumen. A distal head for disrupting occlusions is coupled with the distal end of the ultrasound transmission member and is positioned adjacent the distal end of the catheter body. Some embodiments include improved features such as a bend in the catheter body for enhancing positioning and/or advancement of the catheter.Type: ApplicationFiled: August 4, 2014Publication date: January 22, 2015Inventors: Henry Nita, Jeff Sarge, Simon Nguyen
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Publication number: 20140214064Abstract: Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, an ultrasound catheter includes an elongate flexible catheter body with one or more lumens. An ultrasound transmission member or wire extends longitudinally through the catheter body lumen and, in many embodiments, a guide wire tube also extends through the same lumen. A distal head is fixed to or otherwise mechanically coupled with the distal end of the ultrasound transmission member or wire and is positioned adjacent the distal end of the catheter body. Although the distal end of the catheter body overlaps the distal head, the distal head is not directly affixed to the distal end of the catheter body. Thus, the distal tip may move freely, relative to the distal end of the catheter body when ultrasonic energy is applied through the ultrasound transmission member.Type: ApplicationFiled: April 3, 2014Publication date: July 31, 2014Applicant: FLOWCARDIA, INC.Inventors: Henry Nita, Jeff Sarge, Martinos Tran, Simon Nguyen
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Patent number: 8690819Abstract: Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, an ultrasound catheter includes an elongate flexible catheter body with one or more lumens. An ultrasound transmission member or wire extends longitudinally through the catheter body lumen and, in many embodiments, a guide wire tube also extends through the same lumen. A distal head is fixed to or otherwise mechanically coupled with the distal end of the ultrasound transmission member or wire and is positioned adjacent the distal end of the catheter body. Although the distal end of the catheter body overlaps the distal head, the distal head is not directly affixed to the distal end of the catheter body. Thus, the distal tip may move freely, relative to the distal end of the catheter body when ultrasonic energy is applied through the ultrasound transmission member.Type: GrantFiled: November 9, 2012Date of Patent: April 8, 2014Assignee: Flowcardia, Inc.Inventors: Henry Nita, Jeff Sarge, Martinos Tran, Simon Nguyen