Patents by Inventor Simon Topp-Manske
Simon Topp-Manske has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11827874Abstract: A bioreactor (1; 2; 3) includes a receiving container (10) for receiving a disposable bag (44). A bottom surface (11) of the receiving container (10) is designed to support the disposable bag (44) in the receiving container (10). An outlet opening (5) is formed in the bottom surface (11) and tapers down with respect to the ground for receiving a drain port (45) of the disposable bag (44). The drain port is complementary to the outlet opening (5).Type: GrantFiled: January 25, 2021Date of Patent: November 28, 2023Assignee: Sartorius Stedim Biotech GmbHInventors: Bernward Husemann, Simon Topp-Manske, Bjoern Nickel, Marco Leupold
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Publication number: 20230332091Abstract: A bioreactor system for receiving a disposable bioreactor bag comprises a receiving container having a container wall which defines a receiving space in which the disposable bioreactor bag is received in an operating state of the bioreactor system. A stirring system projects at least partially into the receiving space and is designed and configured to stir a biomedium present in the disposable bioreactor bag in the operating state of the bioreactor system. At least one baffle, which makes the receiving space smaller and differs from the container wall, serves to reduce a laminar flow of the biomedium. A temperature control medium flows through at least part of the at least one baffle, said temperature control medium controlling the temperature of the baffle.Type: ApplicationFiled: June 17, 2021Publication date: October 19, 2023Applicant: Sartorius Stedim Biotech GmbHInventors: Marco Leupold, Simon Topp-Manske, Ute Husemann, Sebastian Ruhl, Sascha Gärtner, Yannick Stapel, Regina Wollschmidt, Gerhard Greller, Thomas Dreher
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Patent number: 11697790Abstract: A probe holder (1), for positioning at least one probe (50) such that the probe (50) at least partially engages in a system (100) for biotechnological uses, comprises a holder base (10) for positioning the probe holder (1) on the system (100) for biotechnological uses and at least one probe positioning means (20), which is designed to position the at least one probe (50) such that the probe (50) extends in a probe extension direction (S; S1, S2, S3, S4). The probe positioning means (20) is positioned on the holder base (10) such that the position of the probe (50) is variably adjustable in a probe extension direction (S; S1, S2, S3, S4).Type: GrantFiled: March 14, 2017Date of Patent: July 11, 2023Assignee: Sartorius Stedim Blotech GmbHInventors: Simon Topp-Manske, Christian Zahnow, Ute Husemann, Bernward Husemann
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Patent number: 11247186Abstract: The invention relates to a mixing system, in particular a bioreactor and/or a pallet tank, for mixing a fluid and/or solid, having a container (4), wherein the fluid and/or the solid and a rotatable stirring element (3) for mixing the fluid and/or the solid are arranged in the interior of the container (4). The mixing system furthermore has a mixing device (1) for receiving the container (4) and a drive device (2) for driving the stirring element (3). The drive device (2) comprises a stator (20) of a three-phase machine (10; 11), the stirring element (3) comprises a rotor (30) of the three-phase machine (10; 11), and the rotor (30) has at least one permanent magnet (31; 31?) and/or at least one short circuit rotor.Type: GrantFiled: July 11, 2016Date of Patent: February 15, 2022Assignee: Sartorius Stedim Biotech GmbHInventor: Simon Topp-Manske
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Publication number: 20220040651Abstract: The present invention relates to a mixing device having a stirring element that comprises: a container for receiving fluids and/or solids; and at least one rotatable stirring element for mixing the fluids and/or solids; wherein the stirring element comprises a first bearing element and a second bearing element which are arranged at or near opposite ends of the stirring element; wherein the first bearing element is mounted on a first face of the container and the second bearing element is mounted on an opposite second face of the container; wherein the first bearing element comprises at least one non-permanently magnetized element such that it can be moved in rotation by externally induced reluctance forces, and wherein the second bearing element is mounted in a contactless manner by externally induced magnetic forces. The invention also relates to a mixing device system.Type: ApplicationFiled: May 17, 2019Publication date: February 10, 2022Applicants: Sartorius Stedim Biotech GmbH, Levitronix GmbHInventors: Lars Böttcher, Marco Leupold, Simon Topp-Manske, Thomas Holenstein, Thomas Nussbaumer
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Patent number: 11124753Abstract: A system for receiving a disposable bag (44) has a receiving container (10) with a container interior for receiving the disposable bag (44) and a temperature-control hollow wall (20) that at least partially surrounds the container interior of the receiving container (10). A temperature-control unit controls the temperature of the container interior by will a temperature-control medium arranged in the temperature-control hollow wall (20) at a maximum pressure of about 1 bar.Type: GrantFiled: March 8, 2016Date of Patent: September 21, 2021Inventors: Bernward Husemann, Simon Topp-Manske, Bjorn Nickel, Marco Leupold
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Publication number: 20210139835Abstract: A bioreactor (1; 2; 3) includes a receiving container (10) for receiving a disposable bag (44). A bottom surface (11) of the receiving container (10) is designed to support the disposable bag (44) in the receiving container (10). An outlet opening (5) is formed in the bottom surface (11) and tapers down with respect to the ground for receiving a drain port (45) of the disposable bag (44). The drain port is complementary to the outlet opening (5).Type: ApplicationFiled: January 25, 2021Publication date: May 13, 2021Inventors: Bernward Husemann, Simon Topp-Manske, Bjoern Nickel, Marco Leupold
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Patent number: 10947489Abstract: A bioreactor (1; 2; 3) includes a receiving container (10) for receiving a disposable bag (44). A bottom surface (11) of the receiving container (10) is designed to support the disposable bag (44) in the receiving container (10). An outlet opening (5) is formed in the bottom surface (11) and tapers down with respect to the ground for receiving a drain port (45) of the disposable bag (44). The drain port is complementary to the outlet opening (5).Type: GrantFiled: March 8, 2016Date of Patent: March 16, 2021Inventors: Bernward Husemann, Simon Topp-Manske, Bjoern Nickel, Marco Leupold
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Publication number: 20200283710Abstract: A container (1, 1b) of a bioreactor (1a, 1b) has a container interior (22) designed for being filled with a medium (8) including a photoreactive material, and designed for at least partially triggering a photochemical reaction of the photoreactive material. The container (1, 1b) has at least one illuminant receiving pouch (11) that is at least partially transparent for an electromagnetic radiation (14), and that is arranged on a illuminant opening (12) within the container interior (22) and is designed to receive at least one illuminant (15, 15a, 15b, 15c, 15d, 15e) from an outer side (A) through the illuminant opening (12, 12a, 12b). The illuminant at least partially irradiates the medium (8) such that the photochemical reaction of the photoreactive material can be triggered by electromagnetic radiation (14) emitted by the illuminant and the illuminant is isolated in relation to the medium (8) by the illuminant receiving pouch (11).Type: ApplicationFiled: September 6, 2018Publication date: September 10, 2020Inventors: Marco Leupold, Bernward Husemann, Simon Topp-Manske, Christian Grimm
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Publication number: 20190031996Abstract: A probe holder (1), for positioning at least one probe (50) such that the probe (50) at least partially engages in a system (100) for biotechnological uses, comprises a holder base (10) for positioning the probe holder (1) on the system (100) for biotechnological uses and at least one probe positioning means (20), which is designed to position the at least one probe (50) such that the probe (50) extends in a probe extension direction (S; S1, S2, S3, S4). The probe positioning means (20) is positioned on the holder base (10) such that the position of the probe (50) is variably adjustable in a probe extension direction (S; S1, S2, S3, S4).Type: ApplicationFiled: March 14, 2017Publication date: January 31, 2019Inventors: Simon Topp-Manske, Christian Zahnow, Ute Husemann, Bernward Husemann
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Publication number: 20180187140Abstract: A bioreactor (1; 2; 3) includes a receiving container (10) for receiving a disposable bag (44). A bottom surface (11) of the receiving container (10) is designed to support the disposable bag (44) in the receiving container (10). An outlet opening (5) is formed in the bottom surface (11) and tapers down with respect to the ground for receiving a drain port (45) of the disposable bag (44). The drain port is complementary to the outlet opening (5).Type: ApplicationFiled: March 8, 2016Publication date: July 5, 2018Inventors: Bernward Husemann, Simon Topp-Manske, Bjoern Nickel, Marco Leupold
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Publication number: 20180163164Abstract: A system for receiving a disposable bag (44) has a receiving container (10) with a container interior for receiving the disposable bag (44) and a temperature-control hollow wall (20) that at least partially surrounds the container interior of the receiving container (10). A temperature-control unit controls the temperature of the container interior by will a temperature-control medium arranged in the temperature-control hollow wall (20) at a maximum pressure of about 1 bar.Type: ApplicationFiled: March 8, 2016Publication date: June 14, 2018Inventors: Bernward HUSEMANN, Simon TOPP-MANSKE, Bjorn NICKEL, Marco LEUPOLD
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Publication number: 20180126345Abstract: The invention relates to a mixing system, in particular a bioreactor and/or a pallet tank, for mixing a fluid and/or solid, having a container (4), wherein the fluid and/or the solid and a rotatable stirring element (3) for mixing the fluid and/or the solid are arranged in the interior of the container (4). The mixing system furthermore has a mixing device (1) for receiving the container (4) and a drive device (2) for driving the stirring element (3). The drive device (2) comprises a stator (20) of a three-phase machine (10; 11), the stirring element (3) comprises a rotor (30) of the three-phase machine (10; 11), and the rotor (30) has at least one permanent magnet (31; 31?) and/or at least one short circuit rotor.Type: ApplicationFiled: July 11, 2016Publication date: May 10, 2018Inventor: Simon Topp-Manske