Patents by Inventor Simona C. BAICU

Simona C. BAICU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cultured pancreas islets
    Patent number: 9963679
    Abstract: Methods of preparing pancreatic islets that may comprise pancreatites are provided. The methods may involve subjecting a pancreas and/or pieces thereof to disruption, such as, for example, an enzyme digest, and seeding the recovered cellular product comprising islets in a culture medium comprising at least a detectable amount of endocrine tissue and/or exocrine tissue.
    Type: Grant
    Filed: October 21, 2011
    Date of Patent: May 8, 2018
    Assignee: LIFELINE SCIENTIFIC, INC.
    Inventors: Michael J. Taylor, Simona C. Baicu
  • Methods for increasing isolation yields of cellular products
    Patent number: 9834756
    Abstract: Methods of isolating cellular products, such as pancreatic islets, may be used in diabetes research and therapeutic transplantation. The methods may involve providing a donor tissue having desired cells and undesired cells, perfusing the donor tissue with a perfusion solution, developing edema during perfusion of the donor tissue to form a swelled tissue, and separating the desired cells from undesired cellular material to obtain a cellular product. The methods may also include disrupting the tissue, and separating the desired cells from undesired cellular material to obtain the cellular product. The methods may result in an increased yield of cellular product that retains sufficient functional integrity to be useful as a transplantation resource.
    Type: Grant
    Filed: July 15, 2011
    Date of Patent: December 5, 2017
    Assignee: LIFELINE SCIENTIFIC, INC.
    Inventors: Michael J. Taylor, Simona C. Baicu, David Kravitz
  • CULTURED PANCREAS ISLETS
    Publication number: 20120107936
    Abstract: Methods of preparing pancreatic islets that may comprise pancreatites are provided. The methods may involve subjecting a pancreas and/or pieces thereof to disruption, such as, for example, an enzyme digest, and seeding the recovered cellular product comprising islets in a culture medium comprising at least a detectable amount of endocrine tissue and/or exocrine tissue.
    Type: Application
    Filed: October 21, 2011
    Publication date: May 3, 2012
    Applicant: CELL & TISSUE SYSTEMS, INC.
    Inventors: Michael J. TAYLOR, Simona C. BAICU
  • METHODS FOR INCREASING ISOLATION YIELDS OF CELLULAR PRODUCTS
    Publication number: 20120015343
    Abstract: Methods of isolating cellular products, such as pancreatic islets, may be used in diabetes research and therapeutic transplantation. The methods may involve providing a donor tissue having desired cells and undesired cells, perfusing the donor tissue with a perfusion solution, developing edema during perfusion of the donor tissue to form a swelled tissue, and separating the desired cells from undesired cellular material to obtain a cellular product. The methods may also include disrupting the tissue, and separating the desired cells from undesired cellular material to obtain the cellular product. The methods may result in an increased yield of cellular product that retains sufficient functional integrity to be useful as a transplantation resource.
    Type: Application
    Filed: July 15, 2011
    Publication date: January 19, 2012
    Applicants: CELL & TISSUE SYSTEMS, INC., LIFELINE SCIENTIFIC, INC.
    Inventors: Michael J. TAYLOR, Simona C. BAICU, David KRAVITZ