Abstract: Arrangements are provided for “smart” functionality with “dumb” containers, such as for determining medication adherence, tracking product use, and validating product authenticity. An acoustic emitter is engaged with a container or other vehicle. Opening the container causes the acoustic emitter to produce an acoustic emission, without requiring power, processing capacity, or sensors. A cell phone or other station receives and registers acoustic emissions, such as by logging opening of the container, verifying authenticity of the acoustic emission, communicating with an oversight system, or similar. Data as may be encoded in an acoustic emission may include vehicle detection data (e.g., logging a container being opened), vehicle information (e.g., lot number, contents name), vehicle validation (e.g., valid or counterfeit numerical code), and audible user recognition (e.g., brand jingles, warning sounds).

Abstract: Disclosed are methods, systems and paradigms for opt-in compliance with regulations. A region in physical space is defined. A condition for the region is defined, the condition being a capability of a communicator such as video recording, still image recording, audio recording, audio output, text messaging, audio communication, or remote connection. The presence and location of a communicator with the capability is detected in the region, and a message is sent to the communicator with a request for a response accepting or rejecting remote deactivation of the capability of the communicator. If an acceptance response is received, the communicator capability is deactivated. If an acceptance response is not received, a notification is generated that includes the lack of acceptance response and the location of the communicator.

Abstract: A target is outputted to an ideal position in 3D space. A viewer indicates the apparent position of the target, and the indication is sensed. An offset between the ideal and apparent positions is determined, and an adjustment determined from the offset such that the apparent position of the ideal position with the adjustment matches the ideal position without the adjustment. The adjustment is made to the first entity and/or a second entity, such that the entities appear to the viewer in the ideal position. The indication may be monocular with a separate indication for each eye, or binocular with a single viewer indication for both eyes. The indication also may serve as communication, such as a PIN input, so that calibration is transparent to the viewer. The method may be continuous, intermittent, or otherwise ongoing over time.

Abstract: Systems and methods for improving the peripheral vision of a subject are disclosed. In one aspect, embodiments of the present disclosure includes a method, which may be embodied on a system, for improving peripheral vision of a subject using a visual marker on a display screen, the method includes, displaying a peripheral target on the display screen, the peripheral target having a visually discernable characteristic and determining whether the subject is able to correctly identify the peripheral target displayed on the display screen using the peripheral vision. The visual marker is intended for viewing using central vision of the subject and the peripheral target is intended for identification using the peripheral vision of the subject.

Abstract: A method, system, apparatus, and/or device for displaying a portion of data so as to not obstruct a portion of a central visual field. The method, system, apparatus, and/or device may include a display configured to display data and a processing device coupled to the display. The processing device may be configured to determine a position of an eye of a viewer with respect to the display, define a first region of the display substantially corresponding with a peripheral vision field of the eye, define a second region of the display substantially corresponding with a central visual field of the eye, send a first portion of the data to be displayed at the first region, and send a second portion of the data to be displayed at the second output region such that a portion of the central visual field is unobstructed by the second portion of the data.

Abstract: An RF signal is provided by a base such as a smart phone. A remote is engaged with a medication container. The remote includes an RFPM, RF signal receiver, LO signal generator, and IF signal emitter. An energizer on the remote provides power only as medication is dispensed. While energized, the RFPM modulates the RF signal with an LO signal to produce an IF signal. The existence of the IF signal (characteristic of the RFPM, RF signal, and LO signal) thus indicates medication has been dispensed. The IF signal is detected in the base, and registered (recorded, displayed, communicated, etc.) as an indication that medication has been dispensed. The remote may be configured as a label applied to or a sleeve engaged with an otherwise “non-smart” container. This provides authenticated data regarding medication adherence, transparent to the user and requiring no additional user actions to register the data.

Abstract: Disclosed are methods, systems and paradigms for opt-in compliance with regulations. A region in physical space is defined. A condition for the region is defined, the condition being a capability of a communicator such as video recording, still image recording, audio recording, audio output, text messaging, audio communication, or remote connection. The presence and location of a communicator with the capability is detected in the region, and a message is sent to the communicator with a request for a response accepting or rejecting remote deactivation of the capability of the communicator. If an acceptance response is received, the communicator capability is deactivated. If an acceptance response is not received, a notification is generated that includes the lack of acceptance response and the location of the communicator.

Abstract: Introduced here are universal modular attachments that can be attached to medication containers. Because a single modular attachment is typically attachable to medication containers of different sizes, the modular attachment can be referred to as a “universal modular attachment.” For example, some universal modular attachments are attachable to any cylindrical eye drop container having a diameter ranging from 20 millimeters (mm) to 27 mm. A connector ring that substantially matches the diameter of the medication container secures the universal modular attachment to the medication container. The connector ring may be fixedly affixed to the medication container, while the universal modular attachment may be detachably connectable to the connector ring. Each universal modular attachment also includes sensor(s) that are configured to detect administrations of medication.

Abstract: Systems and methods for medication management are provided. Some embodiments provide for a portable medication management and monitoring system for eye drop instillation in ocular chronic conditions. At least one embodiment includes a device having one or more of the following elements: (a) a jacket that goes around an eye drop bottle; (b) tactile sensors to detect the user's fingers and generate data to activate the system; (c) motion sensors to detect the motion of the medication bottle when it is grabbed and moved by the user; (d) a wireless communication module to send and receive data to a computer and portable communication devices; and/or (e) a compartment for holding the electronic components.

Abstract: A target is outputted to an ideal position in 3D space. A viewer indicates the apparent position of the target, and the indication is sensed. An offset between the ideal and apparent positions is determined, and an adjustment determined from the offset such that the apparent position of the ideal position with the adjustment matches the ideal position without the adjustment. The adjustment is made to the first entity and/or a second entity, such that the entities appear to the viewer in the ideal position. The indication may be monocular with a separate indication for each eye, or binocular with a single viewer indication for both eyes. The indication also may serve as communication, such as a PIN input, so that calibration is transparent to the viewer. The method may be continuous, intermittent, or otherwise ongoing over time.

Abstract: Arrangements are provided for “smart” functionality such as for tracking medication use to determine adherence, without requiring smart containers therefor. A bin is provided for receiving used/empty containers, packaging, or other discarded material incidental to the use of the medication. Sensors generate signals when the material is deposited within the bin, and a processor determines whether those signals correspond with the incidental material of interest. The processor also may identify when signals correspond with other, spurious material deposited in the bin. Responsive to a positive correspondence, a contextual event such as deposition of a used vial is stored, displayed, communicated, and/or otherwise registered. Contextual events, times therefor, lack of same, etc. are considered to provide authenticated determinations of adherence to a medication regimen.

Abstract: “Smart” functionality is provided to “dumb” containers. A closure such as tape is provided with structural nonuniformity, such as holes punched to weaken the material or polymer printing to strengthen the material. Data is encoded in structural nonuniformity, so when the closure is torn, cut, or otherwise yields the data is encoded in the acoustic emission. The structural nonuniformity also may be readable optically or otherwise. Encoded data may include event detection (logging containers opening), package/product information (e.g., lot numbers, contents), validation (e.g., validation codes to distinguish authentic from counterfeit products), and user recognition (e.g., brand jingles, warning sounds). Closures may be made/dispensed with structural nonuniformity in place, and/or structural nonuniformity may be added to closures already securing a portal. Hand-held systems may dispense and/or modify closures with structural nonuniformity.

Abstract: A therapeutic event such as administering a medication is established. A trigger is established for the therapeutic event, the trigger being a status of some condition. A determination is made as to whether the trigger is present. A prompt is established for the therapeutic event. If the trigger is present, the prompt is delivered to a subject such as a patient. A determination is able to be made as to whether the prompt is delivered, and/or whether the therapeutic event is executed by the subject.

Abstract: An RF signal is provided by a base such as a smart phone. A remote is engaged with a medication container. The remote includes an RFPM, RF signal receiver, LO signal generator, and IF signal emitter. An energizer on the remote provides power only as medication is dispensed. While energized, the RFPM modulates the RF signal with an LO signal to produce an IF signal. The existence of the IF signal (characteristic of the RFPM, RF signal, and LO signal) thus indicates medication has been dispensed. The IF signal is detected in the base, and registered (recorded, displayed, communicated, etc.) as an indication that medication has been dispensed. The remote may be configured as a label applied to or a sleeve engaged with an otherwise “non-smart” container. This provides authenticated data regarding medication adherence, transparent to the user and requiring no additional user actions to register the data.

Abstract: Introduced here are universal modular attachments that can be attached to medication containers. Because a single modular attachment is typically attachable to medication containers of different sizes, the modular attachment can be referred to as a “universal modular attachment.” For example, some universal modular attachments are attachable to any cylindrical eye drop container having a diameter ranging from 20 millimeters (mm) to 27 mm. A connector ring that substantially matches the diameter of the medication container secures the universal modular attachment to the medication container. The connector ring may be fixedly affixed to the medication container, while the universal modular attachment may be detachably connectable to the connector ring. Each universal modular attachment also includes sensor(s) that are configured to detect administrations of medication.

Abstract: Systems and methods for medication management are provided. Some embodiments provide for a portable medication management and monitoring system for eye drop instillation in ocular chronic conditions. At least one embodiment includes a device having one or more of the following elements: (a) a jacket that goes around an eye drop bottle; (b) tactile sensors to detect the user's fingers and generate data to activate the system; (c) motion sensors to detect the motion of the medication bottle when it is grabbed and moved by the user; (d) a wireless communication module to send and receive data to a computer and portable communication devices; and/or (e) a compartment for holding the electronic components.

Abstract: A therapeutic event such as administering a medication is established. A trigger is established for the therapeutic event, the trigger being a status of some condition. A determination is made as to whether the trigger is present. A prompt is established for the therapeutic event. If the trigger is present, the prompt is delivered to a subject such as a patient. A determination is able to be made as to whether the prompt is delivered, and/or whether the therapeutic event is executed by the subject.

Abstract: A method and apparatus for monitoring and/or managing adherence to a medication regimen that involves use of a sensor. Dispensing medicine from a container commonly involves pressure being applied to the container, which results in expansion of the container. In some embodiments, pressure is applied by a user through an aperture of the apparatus. In some embodiments, a processor monitors pressure sensor data from a pressure sensor that is physically coupled to the container and arranged such that activation of the pressure sensor indicates the container has expanded in response to the user applying pressure. A processor analyzes the pressure sensor data to determine whether medicine has been dispensed from the container. A computer system can compare the dispensed medication to a planned medication regimen to determine a state of compliance with the medication regimen.

Abstract: An RF signal is provided by a base such as a smart phone. A remote is engaged with a medication container. The remote includes an RFPM, RF signal receiver, LO signal generator, and IF signal emitter. An energizer on the remote provides power only as medication is dispensed. While energized, the RFPM modulates the RF signal with an LO signal to produce an IF signal. The existence of the IF signal (characteristic of the RFPM, RF signal, and LO signal) thus indicates medication has been dispensed. The IF signal is detected in the base, and registered (recorded, displayed, communicated, etc.) as an indication that medication has been dispensed. The remote may be configured as a label applied to or a sleeve engaged with an otherwise “non-smart” container. This provides authenticated data regarding medication adherence, transparent to the user and requiring no additional user actions to register the data.

Abstract: Arrangements are provided for “smart” functionality with “dumb” containers, such as for tracking medication use to determine adherence. An acoustic emitter such as a whistle is engaged with a container such as an eye drop bottle. An event such as dispensing medication or opening the container causes a characteristic acoustic emission, such as an ultrasonic pitch of specific frequency. The emitter may be purposefully configured to produce the emission, may operate so that the emission is a natural consequence of dispensing medication (or other event), and may operate transparently to the user. The emitter may be part of a larger remote, such as a squeezable air-filled shell with an aperture to accept the container. A cell phone or other station receives the acoustic emission, and if a processor thereof determines that the emission is characteristic of the emitter the event is recorded, transmitted, displayed, or otherwise registered.