Patents by Inventor Sirinporn THAMAPIPOL

Sirinporn THAMAPIPOL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the preparation of beta-substituted gamma-amino carboxylic acids
    Patent number: 9745249
    Abstract: The present invention relates to the preparation of ?-substituted ?-amino carboxylic acids, preferably in enantiomerically enriched or even enantiomerically pure form, by a one-pot conversion of a ?-substituted ?-nitro dicarboxylic acid ester or of a ?-substituted ?-nitro dicarboxylate of general formula to a ?-substituted ?-nitro carboxylic acid and a subsequent reduction of the ?-nitro group to an amine group. In particular, the present invention relates to the preparation of (S)-pregabalin. In addition, the formation of enantiomerically enriched ?-substituted ?-amino carboxylic acids and ?-substituted ?-nitronate carboxylic acid salts are also described.
    Type: Grant
    Filed: June 2, 2015
    Date of Patent: August 29, 2017
    Assignee: SIEGFRIED LTD.
    Inventors: Yoshikazu Suzuki, Irène Lehmann, Hans Ulrich Bichsel, Thomas Bader, Sirinporn Thamapipol
  • METHOD FOR THE PREPARATION OF BETA-SUBSTITUTED GAMMA-AMINO CARBOXYLIC ACIDS
    Publication number: 20170114003
    Abstract: The present invention relates to the preparation of ?-substituted ?-amino carboxylic acids, preferably in enantiomerically enriched or even enantiomerically pure form, by a one-pot conversion of a ?-substituted ?-nitro dicarboxylic acid ester or of a ?-substituted ?-nitro dicarboxylate of general formula to a ?-substituted ?-nitro carboxylic acid and a subsequent reduction of the ?-nitro group to an amine group. In particular, the present invention relates to the preparation of (S)-pregabalin. In addition, the formation of enantiomerically enriched ?-substituted ?-amino carboxylic acids and ?-substituted ?-nitronate carboxylic acid salts are also described.
    Type: Application
    Filed: June 2, 2015
    Publication date: April 27, 2017
    Applicant: SIEGFRIED LTD.
    Inventors: Yoshikazu SUZUKI, Irène LEHMANN, Hans Ulrich BICHSEL, Thomas BADER, Sirinporn THAMAPIPOL