Patents by Inventor Siripragada Rao

Siripragada Rao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070111998
    Abstract: The present invention relates to novel heterocyclic compounds of the general formula (I), as IL-6 inhibitors, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their hydrates, their solvates, their pharmaceutically acceptable salts and compositions, their metabolites and prodrugs thereof. The present invention more particularly provides novel heterocyclic compounds of the general formula (I). Also included is a method for treatment of cancer, cancer cachexia and inflammatory diseases including immunological diseases, particularly those mediated by cytokines such as IL-6, through pSTAT3 inhibition, in a mammal comprising administering an effective amount of a compound of formula (I) as described above.
    Type: Application
    Filed: October 12, 2006
    Publication date: May 17, 2007
    Applicant: ORCHID RESEARCH LABORATORIES, LTD.
    Inventors: Siripragada Rao, Akella Satya Srinivas, Shikha Rani, Gaddam Reddy, Sriram Rajagopal, Uma Ramachandran, Duddu Sharada, Rajagopalan Nirmala, Velaiah Sivasudar, Lakshmanan Manikandan, Ramachandran Balaji
  • Publication number: 20070066569
    Abstract: The present invention is to relate an improved process using anisole as solvent for the preparation of compound of formula (I) and its pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: September 19, 2006
    Publication date: March 22, 2007
    Applicant: ORCHID CHEMICALS & PHARMACEUTICALS LTD.
    Inventors: Udayampalayam Senthilkumar, Thangavel Arulmoli, Venu Lakshmipathi, Siripragada Rao
  • Publication number: 20070060756
    Abstract: The present invention relates to an improved process for the preparation of compound of formula (I), 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine (Desloratadine) or its pharmaceutically acceptable salts thereof, by reacting a compound of formula (II), 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1 piperidinecarboxylic acid ethyl ester (Loratadine) with sodium hydroxide in a solvent mixture of toluene and polyethylene glycol (PEG 400) at reflux temperature.
    Type: Application
    Filed: September 15, 2006
    Publication date: March 15, 2007
    Applicant: ORCHID CHEMICALS & PHARMACEUTICALS LTD.
    Inventors: Veerappan Vijayabaskar, Siripragada Rao, Prabhakaran Kannan, Devasitham Prabhu