Abstract: Embodiments of the technology described herein are based, in part, upon the discovery that NETosis, the formation of neutrophil extracellular traps (NETs) is increased in wounds, in organ fibrosis and in subjects with diabetes. Accordingly, methods for treating wounds, fibrosis and NET associated complications in diabetes are provided. The methods comprise administrating a therapeutically effective amount of at least one anti-NET compound to a subject in need of treatment, e.g. a PAD 4 inhibitor, a DNase, a histone-degrading enzyme; an inhibitor of chromatin decondensation; an antibody against a component of a NET; an inhibitor of NET release, a protease inhibitor, or an elastase inhibitor.

Abstract: The disclosure provides a method for treating and/or preventing graft rejection with A Disintegrin And Metalloproteinase with Thrombospondin type 1 motif, member-13 (ADAMTS13). The disclosure provides a method for increasing ADAMTS13-mediated von Willebrand factor (VWF) cleavage in a subject that received a graft by administering ADAMTS13. The disclosure also provides a method of determining the likelihood that a subject will rejection a graft.

Abstract: Embodiments of the technology described herein are based, in part, upon the discovery that NETosis, the formation of neutrophil extracellular traps (NETs) is increased in wounds, in organ fibrosis and in subjects with diabetes. Accordingly, methods for treating wounds, fibrosis and NET associated complications in diabetes are provided. The methods comprise administrating a therapeutically effective amount of at least one anti-NET compound to a subject in need of treatment, e.g. a PAD 4 inhibitor, a DNase, a histone-degrading enzyme; an inhibitor of chromatin decondensation; an antibody against a component of a NET; an inhibitor of NET release, a protease inhibitor, or an elastase inhibitor.

Abstract: Embodiments of the technology described herein are based, in part, upon the discovery that NETosis, the formation of neutrophil extracellular traps (NETs) is increased in wounds, in organ fibrosis and in subjects with diabetes. Accordingly, methods for treating wounds, fibrosis and NET associated complications in diabetes are provided. The methods comprise administrating a therapeutically effective amount of at least one anti-NET compound to a subject in need of treatment, e.g. a PAD 4 inhibitor, a DNase, a histone-degrading enzyme; an inhibitor of chromatin decondensation; an antibody against a component of a NET; an inhibitor of NET release, a protease inhibitor, or an elastase inhibitor.

Abstract: There is provided a carrier. The carrier comprises an inner lining arranged in the carrier, the lining providing a cavity in which items are carried in the carrier. The carrier includes an illumination system having light transmitting fibers in or at the lining for illumination of the cavity, a light source for feeding lighting to said fibers or otherwise providing illumination in the cavity, a switch for controlling operation of light source, a power source for providing power to illumination system, and a capacitor for controlling duration of illumination of light source.

Abstract: There is provided a carrier. The carrier comprises an inner lining arranged in the carrier, the lining providing a cavity in which items are carried in the carrier. The carrier includes an illumination system having light transmitting fibers in or at the lining for illumination of the cavity, a light source for feeding lighting to said fibers or otherwise providing illumination in the cavity, a switch for controlling operation of light source, a power source for providing power to illumination system, and a capacitor for controlling duration of illumination of light source.

Abstract: A mobile communication device includes a first antenna configured to transmit and receive RF signals, a first capacitive sensor adjacent to the first antenna, a second antenna configured to transmit and receive RF signals, a second capacitive sensor adjacent to the second antenna, a sensing circuit in communication with the first capacitive sensor and the second capacitive sensor, the sensing circuit being that can determine the position of a user's hand adjacent to the first antenna or the second antenna in response to sensing signals received from the first capacitive sensor and the second capacitive sensor, and an antenna switching circuit that can select the first antenna or the second antenna to transmit and receive RF signals to enable wireless communications in response to the position of the user' hand relative to the first antenna and the second antenna as determined by the sensing circuit.

Abstract: A mobile communication device includes a first antenna configured to transmit and receive RF signals, a first capacitive sensor adjacent to the first antenna, a second antenna configured to transmit and receive RF signals, a second capacitive sensor adjacent to the second antenna, a sensing circuit in communication with the first capacitive sensor and the second capacitive sensor, the sensing circuit being that can determine the position of a user's hand adjacent to the first antenna or the second antenna in response to sensing signals received from the first capacitive sensor and the second capacitive sensor, and an antenna switching circuit that can select the first antenna or the second antenna to transmit and receive RF signals to enable wireless communications in response to the position of the user' hand relative to the first antenna and the second antenna as determined by the sensing circuit.

Abstract: A mobile communication device includes a device body, one or more capacitive sensors each having a single electrode that varies depending on a user's hand position in the vicinity of the mobile communication device, an oscillator that can generate an oscillating signal applied to each of the capacitive sensors, and a capacitance-frequency converter circuit that can convert the frequency of the oscillating signal to the capacitance of each of the capacitive sensors. The capacitance-frequency converter circuit can activate a plurality of functions in response to different positions of the user's hand in the vicinity of the device body.