Patents by Inventor Siwei NIE

Siwei NIE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-CD39 antibodies and use thereof
    Patent number: 11970543
    Abstract: Provided herein are anti-CD39 antibodies that inhibit the enzymatic activity of human CD39 and methods of using the same.
    Type: Grant
    Filed: March 2, 2023
    Date of Patent: April 30, 2024
    Assignees: ARCUS BIOSCIENCES, INC., WUXI BIOLOGICS IRELAND LIMITED
    Inventors: Christine Elizabeth Bowman, Ada Pei Xian Chen, Ester Fernandez-Salas, Nigel Pelham Clinton Walker, Xiaoning Zhao, Yaohua Hu, Siwei Nie, JijIe Gu
  • ANTI-CD39 ANTIBODIES AND USE THEREOF
    Publication number: 20240034803
    Abstract: Provided herein are anti-CD39 antibodies that inhibit the enzymatic activity of human CD39 and methods of using the same.
    Type: Application
    Filed: March 2, 2023
    Publication date: February 1, 2024
    Applicants: ARCUS BIOSCIENCES, INC., WUXI BIOLOGICS IRELAND LIMITED
    Inventors: Christine Elizabeth Bowman, Ada Pei Xian Chen, Ester Fernandez-Salas, Nigel Pelham Clinton Walker, Xiaoning Zhao, Yaohua Hu, Siwei Nie, Jijie Gu
  • ANTI-TIM-3 ANTIBODIES AND USES THEREOF
    Publication number: 20210340252
    Abstract: Provided in the present disclosure are anti-TIM-3 antibodies, the methods of hybridoma generation, the nucleic acid molecules encoding the anti-TIM-3 antibodies, expression vectors and host cells used for the expression of anti-TIM-3 antibodies. The disclosure further provides the methods for validating the function of antibodies in vitro and the efficacy of antibodies in vivo. The antibodies of the disclosure provide a very potent agent for the treatment of cancers via modulating immune functions.
    Type: Application
    Filed: December 11, 2019
    Publication date: November 4, 2021
    Applicant: WUXI BIOLOGICS IRELAND LIMITED
    Inventors: Siwei NIE, Yong ZHENG, Jun PAN, Jianqing XU, Jing LI
  • NOVEL ANTI-TIM-3 ANTIBODIES
    Publication number: 20210163590
    Abstract: The present disclosure provides anti-TIM-3 antibodies or antigen-binding fragments thereof, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same, and the uses thereof.
    Type: Application
    Filed: March 19, 2019
    Publication date: June 3, 2021
    Inventors: Siwei NIE, Yong ZHENG, Jing LI