Abstract: This document relates to materials and methods for the production of protein. In one aspect, this document provides a first exogenous nucleic acid construct including a nucleotide sequence encoding an aminolevulinate synthase (ALAS) protein operably linked to a first promoter element, wherein the ALAS includes at least a first heme responsive motif (HRM), and wherein the ALAS includes a mutation in the first HRM, and a second exogenous nucleic acid construct comprising a nucleotide sequence encoding a heme-binding protein, wherein the second exogenous nucleic acid construct including a nucleotide sequence encoding the heme-binding protein is operably linked to the first promoter element or is operably linked to a second promoter element.

Abstract: This document relates to materials and methods for the production of protein. In one aspect, this document provides a nucleic acid construct including a first alcohol oxidase promoter element, wherein the first alcohol oxidase promoter element includes a mutation at one or more nucleotide positions corresponding to any of nucleotide positions 668-734 relative to SEQ ID NO: 28.

Abstract: Methods and materials for genetically engineering methylotrophic yeast are provided.

Abstract: This document relates to materials and methods for the production of protein. In one aspect, this document provides a nucleic acid construct including a first alcohol oxidase promoter element, wherein the first alcohol oxidase promoter element includes a mutation at one or more nucleotide positions corresponding to any of nucleotide positions 668-734 relative to SEQ ID NO: 28.

Abstract: Methods and materials for genetically engineering methylotrophic yeast are provided.

Abstract: This document relates to materials and methods for the production of protein. In one aspect, this document provides a first exogenous nucleic acid construct including a nucleotide sequence encoding an aminolevulinate synthase (ALAS) protein operably linked to a first promoter element, wherein the ALAS includes at least a first heme responsive motif (HRM), and wherein the ALAS includes a mutation in the first HRM, and a second exogenous nucleic acid construct comprising a nucleotide sequence encoding a heme-binding protein, wherein the second exogenous nucleic acid construct including a nucleotide sequence encoding the heme-binding protein is operably linked to the first promoter element or is operably linked to a second promoter element.

Abstract: This document relates to materials and methods for the production of protein. In one aspect, this document provides a nucleic acid construct including a first alcohol oxidase promoter element, wherein the first alcohol oxidase promoter element includes a mutation at one or more nucleotide positions corresponding to any of nucleotide positions 668-734 relative to SEQ ID NO: 28.

Abstract: Methods and materials for genetically engineering methylotrophic yeast are provided.

Abstract: Methods and materials for genetically engineering methylotrophic yeast are provided.

Abstract: One embodiment of the present invention relates to a system that enables a single software application instance to support multiple tenants, wherein each tenant is associated with a separate database. First, the software application instance receives an input, wherein the input requires an operation to be performed on a database of one of the supported tenants. Next, the software application instance identifies the tenant with which the input is associated. The software application instance then obtains a context associated with the tenant. From the context, the software application instance obtains a service object. Finally, the software application invokes a method provided by the service object's class. This enables a data access object, which is encapsulated within the service object, to perform the operation on the database.

Abstract: Methods and materials for genetically engineering methylotrophic yeast are provided.

Abstract: Methods and materials for genetically engineering methylotrophic yeast are provided.

Abstract: Methods and materials for genetically engineering methylotrophic yeast are provided.

Abstract: Methods and materials for genetically engineering methylotrophic yeast are provided.

Abstract: Methods and materials for genetically engineering methylotrophic yeast are provided.

Abstract: Genetically engineered cells and microorganisms are provided that produce fatty alcohols and fatty acids. In particular, engineered microbial cells comprise a modified native gene having ?-ketoacyl-acp synthase activity.

Abstract: Genetically engineered cells and microorganisms are provided that produce fatty alcohols and fatty acids. In particular, engineered microbial cells comprise a modified native gene having ?-ketoacyl-acp synthase activity.

Abstract: The disclosed embodiments provide a system that facilitates management of a financial transaction. During operation, the system obtains transaction data for the financial transaction between a user and an organization from a Short Message Service (SMS) notification on an electronic device of the user. Next, the system determines a category of the financial transaction based on the transaction data. The system also displays the transaction data and the category on the electronic device. Finally, the system uses the displayed transaction data and the displayed category to enable, for the user, management of the financial transaction without accessing the transaction data at the organization.