Abstract: Provided are phototherapeutic needle patches usable for phototherapy by using needle patches capable of injecting drugs or cosmetic substances to patients, and methods of manufacturing the same. A phototherapeutic needle patch may include a patch body attachable to skin of a patient, at least one microneedle protruding from the patch body, one end of the microneedle configured to deliver a drug through stratum corneum of the skin to inner tissues of the skin, and light grooves formed in a concave shape along a length direction of the microneedle in such a manner that therapeutic light radiated from a light source for phototherapy easily penetrates into the skin along the microneedle.

Abstract: A wireless power receiving apparatus which wirelessly charges power according to one embodiment of the present invention includes a substrate, a soft magnetic layer which is laminated on the substrate and is formed with a plurality of patterns including at least 3 lines radiated from predetermined points, and a coil which is laminated on the soft magnetic layer and receives electromagnetic energy radiated from a wireless power transmitting apparatus.

Abstract: Compositions and processes for forming barrier coatings to prevent hydrogen embrittlement of an underlying material are disclosed. The coating can be made up of composite structures of metal and oxide that are alternately deposited onto a substrate for creating a multilayer coated substrate. Such multilayer coating can be incorporated into many contexts in which hydrogen permeation prevention is desired, such as pipelines and manufacture of advanced automotive steels. The process involves depositing a metal layer onto the substrate followed by a metal oxide layer thereon. The interface of the metal layer and the oxide layer can form space-charge zones that decrease hydrogen permeability therethrough.

Abstract: One aspect according to the present disclosure relates to a novel nucleic acid ligand which is a new class of nucleic acid compound, the existence of which was considered impossible in the prior art. The novel nucleic acid ligand has specific binding affinity with respect to at least two different targets having three-dimensional structures, and the binding sites for the at least two targets are formed in or from a single nucleic acid ligand. The novel nucleic acid ligand according the present disclosure can simultaneously solve several problems of existing aptamers that the prior art could not solve. One aspect according to the present disclosure relates to a novel screening method for identifying the above-mentioned novel nucleic acid ligand. The novel screening method uses a step for sequentially contacting at least two different targets having three-dimensional structures to screen a novel nucleic acid ligand that was previously thought impossible.

Abstract: A peptide according to one aspect of the present invention, and a pharmaceutical composition and a skin external preparation containing same promote the growth of individual hair follicle cells and increase the amount of hair growth-related cytokines, thus having a hair tonic, hair growth, or hair growth-promoting effect, and consequently, the effect of effectively treating, ameliorating, or preventing alopecia.

Abstract: The present invention relates to a dianhydride analysis method, which can reliably analyze a dianhydride having high reactivity and low solubility. In addition, the present invention can analyze the structure of impurities by separating the impurities on the basis of having a similar retention time in HPLC analysis, and can analyze the purity of the dianhydride with or without chromophores.

Abstract: An O-phosphoserine (OPS) export protein variant, and a method for producing O-phosphoserine, cysteine, and cysteine derivatives using the same.

Abstract: Disclosed is an energy-efficient retraining method of a generative neural network for domain-specific optimization, including (a) retraining, by a mobile device, a pretrained generative neural network model with respect to some data of a new user dataset, (b) comparing, by the mobile device, the pretrained generative neural network model and a generative neural network model retrained for each layer with each other in terms of a relative change rate of weights, (c) selecting, by the mobile device, specific layers having high relative change rate of weights, among layers of the pretrained generative neural network model, as layers to be retrained, and (d) performing, by the mobile device, weight update for only the layers selected in step (c), wherein only some of all layers are selected and trained in a retraining process that requires a large amount of operation, whereby rapid retraining is performed in the mobile device.

Abstract: The present specification relates to compounds for inhibiting neovascularization factors and use thereof. Furthermore, the present specification relates to methods for treating neovascularization diseases using the compounds.

Abstract: An apparatus for diagnosing an abnormality of a vehicle sensor is provided. The apparatus includes a sensor configured to measure an acceleration and an angular velocity of a vehicle, a camera configured to generate a front time series image frame of the vehicle, and a controller configured to estimate the acceleration and the angular velocity of the vehicle by using the front time series image frame generated by the camera and diagnose an abnormality in the sensor based on the acceleration and the angular velocity of the vehicle estimated by the controller.

Abstract: Peptides are easy to pass through a tissue-blood barrier, have excellent physiological activity in the protective activity of cells, and have an economic advantage due to low production costs. In addition, since there is no side effect of cell proliferation, a pharmaceutical composition containing a peptide of an aspect as an active ingredient can be usefully used in the treatment or prevention of neurological disorders and degenerative brain diseases.

Abstract: The present invention relates to an MDO heat-shrinkable film of a copolymer polyester having excellent thermal resistance. In particular, the present invention provides a copolymer polyester MDO (machine direction orientation) thermoresistant heat-shrinkable film that consists of a copolymer polyester resin including isosorbide and 1,4-cyclohexanedimethanol at an optimized content ratio as a diol component copolymerized with an acid component including terephthalic acid, and having a number average molecular weight of 18,000 g/mol or more, and can be used for labels, cap seals, direct packaging, etc. of various containers due to the high shrink initiation temperature.

Abstract: A method of generating Acknowledgement/Negative Acknowledgement (ACK/NACK) information by a user equipment (UE) in a wireless communication system is discussed. The method includes receiving, by the UE from a base station (BS), a plurality of codewords through a plurality of downlink frequency bands related to a plurality of downlink carriers, wherein the UE is configured with a 1-codeword mode or a 2-codeword mode for each of the plurality of downlink frequency bands independently, and wherein a number of supported codewords is one for the 1-codeword mode or two for the 2-codeword mode; determining, by the UE, a total number of ACK/NACK bits, wherein the total number of ACK/NACK bits is determined based on a total number of the plurality of downlink carriers and the number of supported codewords; and generating, by the UE, a sequence of the ACK/NACK bits based on the total number of the ACK/NACK bits.

Abstract: The present invention relates to a gadolinium-based compound of a Chemical Formula 1, a method for producing the same, and an MRI contrast agent containing the same. [Chemical Formula 1] [structural formula] In chemical formula 1, A and Linker represent linking groups, and RB represents a Rose Bengal-derived part.

Abstract: A peptide is described herein that has: (i) a simple structure compared to existing natural human erythropoietin, thus capable of easily passing through a tissue-blood barrier, (ii) excellent bioactivity with respect to cell-protecting activity, (iii) a low manufacturing cost, thus being economically advantageous, and (iv) no side effects on cell proliferation. Also, a pharmaceutical composition comprising the erythropoietin-derived peptide described herein as an active ingredient is described. The pharmaceutical composition may be used for preventing or treating cell damage-related illnesses, such as stroke, mechanical damage or ischemic damage to the nervous system, myocardial infarction, retinal damage, and diabetes. Also, the described pharmaceutical composition may be used for preventing cell damage.

Abstract: An anti-reflective coating composition is provided. The anti-reflective coating composition of the present invention can be useful in preventing a pull-back phenomenon in which an anti-reflective coating layer tears on a corner of a pattern of a substrate during a heat curing process and improving gap-filling performance of the pattern since a crosslinker is attached to a polymer in the composition and the content of the low-molecular-weight crosslinker in the composition is minimized to regulate a heat curing initiation temperature.

Abstract: Provided are a microorganism producing an L-amino acid or a precursor thereof, and a method of producing an L-amino acid or a precursor thereof using the microorganism.

Abstract: A device for identifying a road surface includes: storage for storing a deep learning-based road surface model; and a controller configured to identify a type of a road surface on which a vehicle is currently traveling, using the road surface model. The device for identifying a road surface can identify a type of a road surface on which the vehicle is traveling based on deep learning and control the terrain mode of the vehicle based on the identified type of the road surface. The type of the road surface on which the vehicle is traveling may be identified with a high accuracy and an optimal terrain mode may be set, thereby improving not only travel stability but also riding comfort of the vehicle.

Abstract: Provided are a method of screening an inhibitor of caspase activity by lipopolysaccharide and a method of screening a therapeutic agent for inflammatory diseases or sepsis using the same. Accordingly, it is possible to develop a caspase-4-specific inhibitor.