Abstract: Compounds capable of mimicking the pyrin-domain of IF116 is provided together with compounds capable of binding to the pyrin-domain of IF116 or a fragment thereof as well as their uses in medicine. Specifically, the compounds are provided for use in the treatment of disorders associated with STING activity, including cancer and immuno-deficient or auto-immune disorders.

Abstract: Provided is a method of updating software and/or firmware of plural devices of a wind turbine, the plural devices being connected in a communication network to a main computing device, the method including: obtaining information regarding a topology of the communication network at the main computing device; obtaining update packages at the main computing device; triggering, by the main computing device, updating all devices for which an update package is present in a topology derived order, in particular staring at a periphery and continuing inwards.

Abstract: The present invention relates to tools for modulating the P62-STING interaction as a method for modulating the innate immune response. The invention relates to compounds which are capable of either inhibiting or potentiating the interaction and thereby induce or prevent the innate immune response relating to STING. Specifically, compounds are provided for use in the treatment of disorders associated with STING activity, including cancer and immuno-deficient or auto-immune disorders.

Abstract: The present invention provides methods of producing a fermented milk product comprising a step wherein milk is fermented, wherein: (a) the fermentation is initiated by a starter culture, which starter culture comprises lactic acid bacteria capable of metabolizing one or several carbohydrates present in the milk, (b) the fermentation is terminated by a decrease of the concentration of the one or several carbohydrates during fermentation, and (c) the decrease is at least also caused by the metabolic activity of the lactic acid bacteria. The invention further provides respective methods comprising a step, wherein at least part of the whey is separated from the fermented milk product.

Abstract: Compounds capable of mimicking the pyrin-domain of IFI16 is provided together with compounds capable of binding to the pyrin-domain of IFI16 or a fragment thereof as well as their uses in medicine. Specifically, the compounds are provided for use in the treatment of disorders associated with STING activity, including cancer and immuno-deficient or auto-immune disorders.

Abstract: The present invention provides methods of producing a fermented milk product comprising a step wherein milk is fermented, wherein: (a) the fermentation is initiated by a starter culture, which starter culture comprises lactic acid bacteria capable of metabolizing one or several carbohydrates present in the milk, (b) the fermentation is terminated by a decrease of the concentration of the one or several carbohydrates during fermentation, and (c) the decrease is at least also caused by the metabolic activity of the lactic acid bacteria. The invention further provides respective methods comprising a step, wherein at least part of the whey is separated from the fermented milk product.

Abstract: Disclosed is a milk beverage comprising: a pectin extracted from a citrus source, the pectin having: (1) a degree of esterification in range of 55% to 65%, and (2) calcium sensitivity index between 10 and 30; wherein the pH of the milk beverage is between 4.3 to 4.5.

Abstract: There is provided a novel approach for generating multilingual text-to-phoneme mappings for use in multilingual speech recognition systems. The multilingual mappings are based on the weighted output from a neural network text-to-phoneme model, trained on data mixed from several languages. The multilingual mappings used together with a branched grammar decoding scheme is able to capture both inter- and intra-language pronunciation variations which is ideal for multilingual speaker independent recognition systems. A significant improvement in overall system performance is obtained for a multilingual speaker independent name dialing task when applying multilingual instead of language dependent text-to-phoneme mapping.