Abstract: A method for creating an engineered landing zone includes delivering a landing zone prosthesis in a radially compressed configuration to a site of an aneurysm within a vessel. The landing zone prosthesis includes a frame, an engineered landing zone, and graft material coupled at a first end to the frame and at a second end to the engineered landing zone. The method further includes radially expanding the frame at the site of the aneurysm while the engineered landing zone remains in the radially compressed configuration longitudinally spaced from the frame, securing to the vessel, longitudinally translating the engineered landing zone such that the engineered landing zone is at least partially disposed within the frame, and radially expanding the engineered landing zone.

Abstract: Devices, methods, and systems for prosthesis delivery to patient vasculature are provided. A prosthesis delivery device provided herein delivers a prosthesis to the vasculature of a patient and permits an operator to deploy the prosthesis using a single action mechanism to deploy the prosthesis at a standard deployment rate and a dual action mechanism to deploy the prosthesis at an accelerated deployment rate. Deploying the prosthesis at an accelerated deployment rate results in alterations to the deployed prosthesis structure because the prosthesis is deployed with increased axial compression that results in the prosthesis having increased radial force.

Abstract: Devices, methods, and systems for prosthesis delivery to patient vasculature are provided. A prosthesis delivery device provided herein delivers a prosthesis to the vasculature of a patient and permits an operator to deploy the prosthesis using a single action mechanism to deploy the prosthesis at a standard deployment rate and a dual action mechanism to deploy the prosthesis at an accelerated deployment rate. Deploying the prosthesis at an accelerated deployment rate results in alterations to the deployed prosthesis structure because the prosthesis is deployed with increased axial compression that results in the prosthesis having increased radial force.

Abstract: Devices, methods, and systems for prosthesis delivery to patient vasculature are provided. A prosthesis delivery device provided herein delivers a prosthesis to the vasculature of a patient and permits an operator to deploy the prosthesis using a single action mechanism to deploy the prosthesis at a standard deployment rate and a dual action mechanism to deploy the prosthesis at an accelerated deployment rate. Deploying the prosthesis at an accelerated deployment rate results in alterations to the deployed prosthesis structure because the prosthesis is deployed with increased axial compression that results in the prosthesis having increased radial force.

Abstract: A primary stent-graft is deployed into a primary vessel to exclude an aneurysm. To maintain perfusion to a branch vessel covered by the primary stent-graft, a gutter filling stent-graft is deployed in parallel to the primary stent-graft. The gutter filling stent-graft includes a balloon that is pressurized and inflated by the patient's own blood thereby sealing any gutters formed around the gutter filling stent-graft. By sealing the gutters, the chance of type I endoleaks, migrations, and overall failure to exclude the aneurysm is minimized.

Abstract: A stent-graft prosthesis includes a tubular graft and a stent coupled to the tubular graft via a plurality of stitches. The stent has a sinusoidal pattern defined by a plurality of crowns and a plurality of struts. The stitches form a stitch path having a sinusoidal pattern that corresponds to the sinusoidal pattern of the stent. A width of curved segments of the stitch path that are disposed over crowns of the stent is configured to permit relative longitudinal movement between the stents and the tubular graft. A width of intermediate segments of the stitch path that are disposed over struts of the stent may be configured to restrict or permit relative circumferential movement between the stents and the tubular graft. The stitch path may include a plurality of transverse stitches in order to prevent exposure of the crowns beyond the stitch path.

Abstract: A primary stent-graft is deployed into a primary vessel to exclude an aneurysm. To maintain perfusion to a branch vessel covered by the primary stent-graft, a gutter filling stent-graft is deployed in parallel to the primary stent-graft. The gutter filling stent-graft includes a balloon that is pressurized and inflated by the patient's own blood thereby sealing any gutters formed around the gutter filling stent-graft. By sealing the gutters, the chance of type I endoleaks, migrations, and overall failure to exclude the aneurysm is minimized.

Abstract: A stent-graft prosthesis includes a tubular graft and a stent coupled to the tubular graft via a plurality of stitches. The stent has a sinusoidal pattern defined by a plurality of crowns and a plurality of struts. The stitches form a stitch path having a sinusoidal pattern that corresponds to the sinusoidal pattern of the stent. A width of curved segments of the stitch path that are disposed over crowns of the stent is configured to permit relative longitudinal movement between the stents and the tubular graft. A width of intermediate segments of the stitch path that are disposed over struts of the stent may be configured to restrict or permit relative circumferential movement between the stents and the tubular graft. The stitch path may include a plurality of transverse stitches in order to prevent exposure of the crowns beyond the stitch path.