Abstract: The invention relates to a multifunctional germacrene-D synthase and a polynucleotide encoding it. Included also are genetic constructs, transgenic organisms, plant selection methods and biofermentation methods. The enzyme may be used to prepare germacrene-D and/or other sesquiterpenes such as germacrene-D, delta-cadinene, gamma-cadinene, gamma-muurolene, gamma-elemene, delta-elemene, elemol or germacrene-B.

Abstract: The invention relates to a multifunctional germacrene-D synthase and a polynucleotide encoding it. Included also are genetic constructs, transgenic organisms, plant selection methods and biofermentation methods. The enzyme may be used to prepare germacrene-D and/or other sesquiterpenes such as germacrene-D, delta-cadinene, gamma-cadinene, gamma-muurolene, gamma-elemene, delta-elemene, elemol or germacrene-B.

Abstract: The present invention provides an isolated alpha-farnesene synthase and polynucleotide sequences encoding the enzyme. The invention also provides nucleic acid constructs, vectors and host cells incorporating the polynucleotide sequences. It further relates to the production of alpha-farnesene using the enzyme and modulation of alpha-farnesene synthesis in plants and selection of plants with altered alpha-farnesene synthase activity.

Abstract: A system and method for assessing the statistical and clinical acceptance of a new medical service or changes in products used by a clinical laboratory or hospital, and providing documentation of validation. The system and method includes an information exchange mechanism, such as an internet, extranet, compact disc (e.g., CD-ROM) or text-based mechanism to establish a systematic approach between a provider and client for collecting, reviewing and providing information to demonstrate the clinical validity of new or modified products. The collected information and user requests are evaluated using tools such as an analytical array to determine required protocols, limits and subsequent tests needed to demonstrate the clinical validity of products, and thereafter, to provide a report to show validation of the change.

Abstract: The present invention is a syringe tip cap comprising a bottom portion, a top portion, an annular skirt extending therebetween and a plug that projects proximally from the bottom portion so as to be telescoped into the passage of a syringe tip. The plug provides means to allow air to be vented from the syringe with contacting the user. The syringe tip cap of the present invention also provides the user with an indication by tactile and visual feedback that the syringe has been vented.

Abstract: The present invention is a syringe tip cap comprising a bottom portion, a top portion, an annular skirt extending therebetween and a plug that projects proximally from the bottom portion so as to be telescoped into the passage of a syringe tip. The plug provides means to allow air to be vented from the syringe with contacting the user. The syringe tip cap of the present invention also provides the user with an indication by tactile and visual feedback that the syringe has been vented.