Patents by Inventor Somesh Sharma

Somesh Sharma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1-Alkylpiperazinyl-Pyrrolidin-2,5-Dione Derivatives as Adrenergic Receptor Antagonists
    Publication number: 20070219216
    Abstract: This invention relates to ?1a and/or ?1d adrenergic receptor antagonists of formula 1 Compounds disclosed herein can function as ?1a and/or ?1d adrenergic receptor antagonists and can be used for the treatment of diseases or disorders mediated through ?1a and/or ?1d adrenergic receptors. Compounds disclosed herein can be used for the treatment of benign prostatic hyperplasia and related symptoms thereof. Compounds disclosed herein can also be used for the treatment of lower urinary tract symptoms associated with or without benign prostatic hyperplasia. The invention also relates to a process for the preparation of compounds disclosed herein, pharmaceutical compositions containing these compounds and the methods of treating diseases or disorders mediated through ?1a and/or ?1d receptors.
    Type: Application
    Filed: October 14, 2004
    Publication date: September 20, 2007
    Inventors: Nitya Anand, Mohammad Salman, Somesh Sharma, Gobind Kapkoti, Praful Gupta, Anurag Mishra
  • Carboximide derivatives as useful uro-selective alpha-1a adrenoceptor blockers
    Publication number: 20060247249
    Abstract: Novel carboximide derivatives, which selectively inhibit binding to the ?1A adrenergic receptor, a receptor which has been shown to be important in the treatment of benign prostatic hyperplasia. The compounds of the present invention are potentially useful in the treatment of benign prostatic hyperplasia.
    Type: Application
    Filed: November 16, 2005
    Publication date: November 2, 2006
    Inventors: Mohammad Salman, Gyan Yadav, Somesh Sharma, Gobind Kapkoti, Anita Chugh, Jang Gupta, Nitya Anand
  • Alpha, omega-dicarboximide derivatives as useful uro-selective a1a adrenoceptor blockers
    Publication number: 20050228180
    Abstract: Novel ?,?-dicarboximide derivatives which selectively inhibit binding to the ?-,1A? adrenergic receptor, a receptor which has been shown to be important in the treatment of benign prostatic hyperplasia. The compounds of the present invention are potentially useful in the treatment of benign prostatic hyperplasia.
    Type: Application
    Filed: April 8, 2002
    Publication date: October 13, 2005
    Inventors: Mohammad Salman, Gyan Yadav, Somesh Sharma, Gobind Kapkoti, Anita Chugh, Jang Gupta, Nitya Anand
  • MHC class II .beta. chain/peptide complexes useful in ameliorating deleterious immune responses
    Patent number: 5734023
    Abstract: The present invention is directed to complexes comprising an isolated MHC subunit component, an antigenic peptide and, in some cases, an effector component. The antigenic peptide is associated with the antigen binding site of the MHC subunit component. These complexes are useful in treating autoimmune disease.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 31, 1998
    Assignee: Anergen Inc.
    Inventors: Bishwajit Nag, Brian R. Clark, Somesh Sharma, Harden McConnell