Abstract: One aspect of the present invention relates to magnetophoretic devices for cell clarification. In one embodiment, the magnetophoretic device is a counter-current device, comprising a plurality of pairs of magnets selected from the group consisting of permanent magnets and electromagnets; a chain rotated by a motor; tubing; a feed inlet; and a clarified feed outflow. In another embodiment, the magnetophoretic device is a quadrupole device, comprising four magnets selected from the group consisting of permanent magnets and electromagnets; and a cylindrical column. Another aspect of the invention relates generally to a method of separating non-magnetic particles from a magnetic fluid mixture, comprising the steps of combining a magnetic fluid with a sample comprising non-magnetic particles and non-magnetic fluid to form a mixture; subjecting said mixture to a degrading magnetic field; and isolating a portion of the non-magnetic particles from said mixture.