Abstract: An electrodialysis apparatus includes a sample chamber including first and second dialysis membranes and filled with a sample between the first dialysis membrane and the second dialysis membrane, an anode chamber including an anode and filled with a first chamber solution between the anode and the first dialysis membrane, and a cathode chamber including a cathode and filled with a second chamber solution between the cathode and the second dialysis membrane. In particular, when a voltage is applied to the anode and the cathode, ionic materials of the sample move to the anode and cathode chambers.

Abstract: A micro mass measuring apparatus includes a cantilever on which a subject is attached, a piezoelectric element formed on the cantilever, an oscillation circuit for actively vibrating the cantilever and providing a varied resonance frequency by the subject, and a frequency measuring device for measuring a resonance frequency of the cantilever.

Abstract: A gas sensor includes a substrate having a plurality of through holes, a pair of electrodes disposed on the substrate, wherein the plurality of through holes are disposed between the pair of electrodes and a plurality of carbon nanotubes covering at least a portion of the plurality of through holes, wherein at least a portion of the plurality of carbon nanotubes is connected with the pair of electrodes.

Abstract: An optical detection device for biochemically analyzing samples of microfluidic chips such as DNA chips or protein chips is provided. The optical detection device includes a light source for generating excitation light to excite a sample, a detection plate having an optical waveguide with the sample mounted thereon, a linear symmetry lens for shaping the excitation light into a desired shape having a uniform intensity distribution and transmitting it to the detection plate, and a detector for detecting radiation from the sample.

Abstract: A method of positively detecting toxic materials within a sample, the method including contacting sub-mitochondrial particles having competent mitochondrial enzymes formed from inner membranes of mitochondria, an electron donor which transmits electrons to an electron transfer system of the sub-mitochondrial particles and the sample, and forming reaction resultants, adjusting a pH of a pH indicator which change color according to a change in pH, adding the pH indicators to each reaction resultant and identifying color changes of the pH indicator. Also provided is a kit for positively detecting toxic materials within a sample.

Abstract: A robot vacuum cleaner having a microbe sensing function is provided. The robot vacuum cleaner includes: a cleaner body which automatically travels in an area to be cleaned; a suction unit which sucks dust in the area to be cleaned into a specific space included in the cleaner body; a microbe contamination sensor which detects a microbe contamination in the area to be cleaned; and a sterilizing unit which sterilizes a corresponding portion according to a microbe contamination measuring signal generated from the microbe contamination sensor. Accordingly, a robot vacuum cleaner directly measures a level of microbe contamination to perform a sterilizing operation according to the result obtained from measurement. As a result, the sterilizing operation is performed sufficiently in a severely contaminated area, the sterilizing operation is performed in a general manner in other areas, and thus a cleaning operation can be rapidly carried out.

Abstract: Provided is a sensor for detecting a biomolecule, which includes: a substrate; a first material, immobilized on the substrate, having a cavity structure; a secondary material capable of selectively binding to the cavity structure of the first material and having electrochemical activity; and a probe biomolecule immobilized to the secondary material. A method of manufacturing the biomolecule detection sensor and a method of detecting a biomolecule using the biomolecule detection sensor are also provided. Therefore, a target biomolecule can be easily detected using an electrochemical reaction with high accuracy within a short time. Furthermore, there is no need to elaborately design probes, and thus, the biomolecule detection sensor can be easily manufactured. In addition, label-free detection is possible, which simplifies a detection process, and there is no need to use expensive auxiliary equipment.

Abstract: A method of manufacturing a DNA (deoxyribonucleic acid) chip is provided. The DNA chip has a plurality of transistors formed on a substrate and an organic layer and a DNA probe sequentially stacked on a gate of the transistor. The method includes forming an inter-layer insulation layer on the substrate to cover the transistors, planarizing the inter-layer insulation layer, forming at least two contact holes exposing gate electrodes of the transistors in the inter-layer insulation layer, selectively forming organic layers on the exposed gate electrodes, attaching a first DFR (dry film resist) layer to the upper surface of the inter-layer insulation layer to cover the contact holes, removing a portion of the first DFR layer covering a first contact hole among the contact holes, attaching a first DNA probe to the organic layers in the first contact hole, and removing a remaining portion of the first DFR layer.

Abstract: An ion exchangeable mixture containing a polymeric compound consisting of an ion exchange resin, an acrylamide mixture containing at least one bisacrylamide and at least one acrylamide, and a copolymer obtained by reacting the polymeric compound with the acrylamide mixture, and a method of producing the same are provided. The ion exchangeable membrane produced by using the ion exchangeable mixture has significantly smaller electric resistance than conventional ion exchangeable membranes, and has excellent selective permeability because the ion exchangeable membrane is electrically charged. The ion exchangeable membrane can be produced under very mild production conditions, and thus can be produced very easily. Furthermore, the ion exchangeable membrane can be also formed into film during a crosslinking reaction in a solvent of water, and thus is advantageous in that the ion exchangeable membrane can be freely produced into desired sizes, shapes and forms.

Abstract: Provided is a method of manufacturing a microfludic device in which coating film patterns made of a coupling agent are formed in microchannels. The method includes: forming the coating film patterns made of the coupling agent on a Si substrate; selectively oxidizing coupling agent-free regions of the Si substrate having thereon the coating film patterns made of the coupling agent using an oxidizing agent with an oxidation potential from 1 to 2 V; and adhering a PDMS (polydimethylsiloxane) microchannel structure to the selectively oxidized Si substrate to form the microchannels.

Abstract: A packing device used to pack a sample inlet formed in an upper cover of a chamber is provided. The packing device has an air vent formed in the surface of an upper portion of the sample inlet contacting a cap or in the surface of a lower portion of the cap contacting the sample inlet. The movement of the sample solution in the chamber can be prevented by using a structural design in which air pressure generated due to the volume of a packing cap inserted into the sample inlet after the sample is injected into the chamber through the sample inlet to react with reaction materials, such as biomolecules, is not generated inside of the chamber. In addition, in a hybridization chamber in which a biochip is placed, the spot area on the biochip can be effectively agitated with the sample solution, thus increasing hybridization efficiency.

Abstract: Provided are a microfluidic chip for multiple bioassay and a method of manufacturing the same. The method includes: forming microfluidic channels by coupling a channel structure having grooves for sample channels and probe channels in a bottom surface and a substrate; forming probe immobilization regions at intersections between the probe channels and the sample channels; and forming blocking walls in the probe channels before and after each of the probe immobilization regions to prevent mixing of target sample. Since the probes are immobilized in the microfluidic channels after the formation of the microfluidic channels, difficulty in connecting fluidic channels after the immobilization of probes on a substrate can be removed. In addition, a microfluidic platform for a multiple bioassay into which a plurality of samples can be simultaneously loaded can be formed.

Abstract: Provided is a hybridization system for hybridizing a biochip including: a chamber device including at least a hybridization chamber including a support for a biochip and a first cover having a sample inlet; an agitation device including: two air channels connected to ends of the hybridization chamber; two valves disposed in the air channels; an integrated air channel to which the two air channels are connected; and an air pump disposed in the integrated air channel; and a washing and drying device including: a flow channel connected to one of the two air channels through a branched valve; a flow pump disposed in the flow channel; and a buffer inlet disposed opposite the flow channel.

Abstract: Provided is an agitation device used to agitate a solution in a hybridization chamber, the agitation device including: the hybridization chamber; first and second air channels connected to ends of the hybridization chamber; a first valve disposed in the first air channel; a second valve disposed in the second air channel; an integrated air channel connecting the first and second air channels; and a pump disposed in the integrated air channel. The agitation device is suitable for effective diffusion of a sample when performing hybridization using a DNA chip. Therefore, a probe can be effectively hybridized with a target material.

Abstract: Provided is a lysis method for cells or viruses, including: immobilizing a metal-ligand complex on a solid support; and mixing the complex immobilized on the support with a cell or virus solution. According to the lysis method, by immobilizing a chemical on a solid support to perform cell lysis, the dilution problem according to the addition of a cell lysis solution can be resolved and a separate process of removing the chemical is not required so as to reduce the steps upon LOC implementation. In addition, since a variety of solid supports, such as chips, beads, nanoparticles etc. can be used, cell lysis apparatuses of various forms can be fabricated.

Abstract: A biochip with a radio frequency (RF) identification (ID) chip attached thereto, a hybridization system, and a hybridization management method are provided. Probes used for analyzing living body molecules are highly integrated on a substrate of the biochip, and biochip information including information obtained in the process of combining the living body molecules with the probes of the biochip is recorded in the RF ID tag of the biochip. Accordingly, it is possible to efficiently manage the biochip information using the RF ID tag and to prevent the biochip from being reused.

Abstract: An optical detection device for biochemically analyzing samples of microfluidic chips such as DNA chips or protein chips is provided. The optical detection device includes a light source for generating excitation light to excite a sample, a detection plate having an optical waveguide with the sample mounted thereon, a linear symmetry lens for shaping the excitation light into a desired shape having a uniform intensity distribution and transmitting it to the detection plate, and a detector for detecting radiation from the sample.

Abstract: Provided is a microarray substrate. The microarray substrate includes a patterned photoresist film having one or more spot regions therein. The photoresist film can be detached from the substrate.

Abstract: A micro mass measuring apparatus includes a cantilever on which a subject is attached, a piezoelectric element formed on the cantilever, an oscillation circuit for actively vibrating the cantilever and providing a varied resonance frequency by the subject, and a frequency measuring device for measuring a resonance frequency of the cantilever.

Abstract: Provided is a method of treating a surface of a substrate used in a biochemical reaction system, the method including forming a polymer film on the surface by vapor deposition of a compound of formula (1) below and a compound of formula (2) below: