Patents by Inventor Sophia Pesotchinsky
Sophia Pesotchinsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8012121Abstract: Two renal delivery members have two distal ports that are adapted to be positioned within two renal arteries via their corresponding renal ostia at unique locations along an abdominal aortic wall. A proximal coupler assembly is outside the body and is coupled to deliver material to the two distal ports for bi-lateral renal therapy. One or both of the delivery members may be self-cannulating into the corresponding renal ostium, or may be controllably steered into the respective ostium. Non-occlusive anchors may be coupled with one or both of the delivery members at anchoring positions in the renal artery or abdominal aorta to secure the renal delivery member within the renal artery. Renal-active fluid agents are coupled to the bi-lateral delivery system. Another renal therapy system cannulates a renal vein from the vena cava and controls a retrograde delivery of agents to the respective kidney.Type: GrantFiled: June 26, 2007Date of Patent: September 6, 2011Assignee: AngioDynamics, Inc.Inventors: Harry B. Goodson, IV, Jeffrey M. Elkins, Samir R. Patel, Aurelio Valencia, Ricardo Aboytes, Craig A. Ball, Randy J. Kesten, Andrew K. Kramer, Sam G. Payne, Sophia Pesotchinsky, Michael H. Rosenthal
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Patent number: 7914503Abstract: Two renal delivery members have two distal ports that are adapted to be positioned within two renal arteries via their corresponding renal ostia at unique locations along an abdominal aortic wall. A proximal coupler assembly is outside the body and is coupled to deliver material to the two distal ports for bi-lateral renal therapy. One or both of the delivery members may be self-cannulating into the corresponding renal ostium, or may be controllably steered into the respective ostium. Non-occlusive anchors may be coupled with one or both of the delivery members at anchoring positions in the renal artery or abdominal aorta to secure the renal delivery member within the renal artery. Renal-active fluid agents are coupled to the bi-lateral delivery system. Another renal therapy system cannulates a renal vein from the vena cava and controls a retrograde delivery of agents to the respective kidney.Type: GrantFiled: March 16, 2005Date of Patent: March 29, 2011Assignee: Angio DynamicsInventors: Harry B. Goodson, IV, Jeffrey M. Elkins, Samir R. Patel, Aurelio Valencia, Ricardo Aboytes, Craig A. Ball, Randy J. Kesten, Andrew W. Kramer, Sam G. Payne, Sophia Pesotchinsky, Michael H. Rosenthal
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Patent number: 7780628Abstract: Methods and apparatus are provided for treating congestive heart by actively or passively enhancing perfusion to the renal arteries. A first embodiment comprises a specially configured balloon catheter and extracorporeal pump, wherein the pump operates in a “once-through” fashion or alternating volume displacement mode. In another embodiment the catheter includes a pair of balloons to isolate a region of the aorta, and a third balloon that directs flow into the renal arteries. In still further embodiments, a stent or cuff having a constricted region is deployed in or around the aorta, respectively, to create a backpressure upstream of the stent or cuff. Methods of enhancing renal perfusion also are provided.Type: GrantFiled: May 1, 2000Date of Patent: August 24, 2010Assignee: AngioDynamics, Inc.Inventors: Gad Keren, Ascher Shmulewitz, Benjamin Spenser, Michael Arad, Randy J. Kesten, Sophia Pesotchinsky, Michael H. Rosenthal, Andrew W. Kramer, Sam G. Payne
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Patent number: 7766892Abstract: Methods and apparatus are provided for treating congestive heart by actively or passively enhancing perfusion to the renal arteries. A first embodiment comprises a specially configured balloon catheter and extracorporeal pump, wherein the pump operates in a “once-through” fashion or alternating volume displacement mode. In another embodiment the catheter includes a pair of balloons to isolate a region of the aorta, and a third balloon that directs flow into the renal arteries. In still further embodiments, a stent or cuff having a constricted region is deployed in or around the aorta, respectively, to create a backpressure upstream of the stent or cuff. Methods of enhancing renal perfusion also are provided.Type: GrantFiled: May 21, 2002Date of Patent: August 3, 2010Inventors: Gad Keren, Ascher Shmulewitz, Benjamin Spenser, Michael Arad, Randy J. Kesten, Sophia Pesotchinsky, Michael H. Rosenthal, Andrew W. Kramer, Sam G. Payne
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Patent number: 7481803Abstract: A catheter for delivering a therapeutic or diagnostic agent to a branch blood vessel of a major blood vessel, generally comprising an elongated shaft having at least one lumen in fluid communication with an agent delivery port in a distal section of the shaft, an expandable tubular member on the distal section of the shaft, and a radially expandable member on the tubular member. The tubular member is configured to extend within the blood vessel up-stream and down-stream of a branch vessel, and has an interior passageway which is radially expandable within the blood vessel to separate blood flow through the blood vessel into an outer blood flow stream exterior to the tubular member and an inner blood flow stream within the interior passageway of the tubular member.Type: GrantFiled: April 23, 2003Date of Patent: January 27, 2009Assignee: FlowMedica, Inc.Inventors: Randy J. Kesten, Michael H. Rosenthal, Sam G. Payne, Andrew K. Kramer, Sophia Pesotchinsky
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Publication number: 20080103442Abstract: A catheter for delivering a therapeutic or diagnostic agent to a branch blond vessel of a major blood vessel comprises an elongated shaft having at least one lumen in fluid communication with an agent delivery port in a distal section of the shaft, an expandable tubular member on the distal section of the shaft, and a radially expandable member on the tubular member. The tubular member is configured to extend within the blood vessel up-stream and down-stream of a branch vessel, and has an interior passageway which is radially expandable within the blood vessel to separate blood flow through the blood vessel into an outer blood flow stream exterior to the tubular member and an inner blood flow stream within the interior passageway of the tubular member.Type: ApplicationFiled: January 2, 2008Publication date: May 1, 2008Applicant: FLOWMEDICA, INC.Inventors: Randy Kesten, Michael Rosenthal, Sam Payne, Andrew Kramer, Sophia Pesotchinsky
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Patent number: 7335192Abstract: Methods and apparatus are provided for treating congestive heart by actively or passively enhancing perfusion to the renal arteries. A first embodiment comprises a specially configured balloon catheter and extracorporeal pump, wherein the pump operates in a “once-through” fashion or alternating volume displacement mode. In another embodiment the catheter includes a pair of balloons to isolate a region of the aorta, and a third balloon that directs flow into the renal arteries. In still further embodiments, a stent or cuff having a constricted region is deployed in or around the aorta, respectively, to create a backpressure upstream of the stent or cuff. Methods of enhancing renal perfusion also are provided.Type: GrantFiled: May 13, 2003Date of Patent: February 26, 2008Assignee: FlowMedica, Inc.Inventors: Gad Keren, Ascher Shmulewitz, Benjamin Spenser, Michael Arad, Randy J Kesten, Sophia Pesotchinsky, Michael H. Rosenthal, Andrew W. Kramer, Sam G. Payne
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Patent number: 7329236Abstract: A catheter for delivering a therapeutic or diagnostic agent to a branch blond vessel of a major blood vessel comprises an elongated shaft having at least one lumen in fluid communication with an agent delivery port in a distal section of the shaft, an expandable tubular member on the distal section of the shaft, and a radially expandable member on the tubular member. The tubular member is configured to extend within the blood vessel up-stream and down-stream of a branch vessel, and has an interior passageway which is radially expandable within the blood vessel to separate blood flow through the blood vessel into an outer blood flow stream exterior to the tubular member and an inner blood flow stream within the interior passageway of the tubular member.Type: GrantFiled: September 7, 2005Date of Patent: February 12, 2008Assignee: FlowMedica, Inc.Inventors: Randy J. Kesten, Michael H. Rosenthal, Sam G. Payne, Andrew W. Kramer, Sophia Pesotchinsky
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Publication number: 20070249997Abstract: Two renal delivery members have two distal ports that are adapted to be positioned within two renal arteries via their corresponding renal ostia at unique locations along an abdominal aortic wall. A proximal coupler assembly is outside the body and is coupled to deliver material to the two distal ports for bi-lateral renal therapy. One or both of the delivery members may be self-cannulating into the corresponding renal ostium, or may be controllably steered into the respective ostium. Non-occlusive anchors may be coupled with one or both of the delivery members at anchoring positions in the renal artery or abdominal aorta to secure the renal delivery member within the renal artery. Renal-active fluid agents are coupled to the bi-lateral delivery system. Another renal therapy system cannulates a renal vein from the vena cava and controls a retrograde delivery of agents to the respective kidney.Type: ApplicationFiled: June 26, 2007Publication date: October 25, 2007Applicant: FlowMedica, Inc.Inventors: Harry Goodson, Jeffrey Elkins, Samir Patel, Aurelio Valencia, Ricardo Aboytes, Craig Ball, Randy Kesten, Andrew Kramer, Sam Payne, Sophia Pesotchinsky, Michael Rosenthal
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Patent number: 7122019Abstract: A catheter for delivering a therapeutic or diagnostic agent to a branch blood vessel of a major blood vessel, generally comprising an elongated shaft having at least one lumen in fluid communication with an agent delivery port in a distal section of the shaft, an expandable tubular member on the distal section of the shaft, and a radially expandable member on the tubular member. The tubular member is configured to extend within the blood vessel up-stream and down-stream of a branch vessel, and has an interior passageway which is radially expandable within the blood vessel to separate blood flow through the blood vessel into an outer blood flow stream exterior to the tubular member and an inner blood flow stream within the interior passageway of the tubular member. The radially expandable member is located down-stream of the shaft agent delivery port, and has an expanded configuration with an outer diameter larger than an outer diameter of the tubular member.Type: GrantFiled: November 28, 2000Date of Patent: October 17, 2006Assignee: Flowmedica Inc.Inventors: Randy J. Kesten, Michael H. Rosenthal, Sam G. Payne, Andrew K. Kramer, Sophia Pesotchinsky
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Publication number: 20060189960Abstract: A catheter for delivering a therapeutic or diagnostic agent to a branch blond vessel of a major blood vessel comprises an elongated shaft having at least one lumen in fluid communication with an agent delivery port in a distal section of the shaft, an expandable tubular member on the distal section of the shaft, and a radially expandable member on the tubular member. The tubular member is configured to extend within the blood vessel up-stream and down-stream of a branch vessel, and has an interior passageway which is radially expandable within the blood vessel to separate blood flow through the blood vessel into an outer blood flow stream exterior to the tubular member and an inner blood flow stream within the interior passageway of the tubular member.Type: ApplicationFiled: September 7, 2005Publication date: August 24, 2006Applicant: FlowMedica, Inc.Inventors: Randy Kesten, Michael Rosenthal, Sam Payne, Andrew Kramer, Sophia Pesotchinsky
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Publication number: 20060067972Abstract: Methods and devices are provided to preferentially deliver biologically active substances to a patient's renal artery, particularly for the treatment of congestive heart failure. The apparatus will comprise an implantable depot which may be in the form of a biodegradable vascular implant, a replenishable reservoir, a drug pump, or combinations thereof. The reservoirs will preferentially be refillable using needles or other transcutaneous techniques.Type: ApplicationFiled: June 23, 2005Publication date: March 30, 2006Applicant: FlowMedica, Inc.Inventors: Randy Kesten, Sophia Pesotchinsky
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Publication number: 20060036218Abstract: Two renal delivery members have two distal ports that are adapted to be positioned within two renal arteries via their corresponding renal ostia at unique locations along an abdominal aortic wall. A proximal coupler assembly is outside the body and is coupled to deliver material to the two distal ports for bi-lateral renal therapy. One or both of the delivery members may be self-cannulating into the corresponding renal ostium, or may be controllably steered into the respective ostium. Non-occlusive anchors may be coupled with one or both of the delivery members at anchoring positions in the renal artery or abdominal aorta to secure the renal delivery member within the renal artery. Renal-active fluid agents are coupled to the bi-lateral delivery system. Another renal therapy system cannulates a renal vein from the vena cava and controls a retrograde delivery of agents to the respective kidney.Type: ApplicationFiled: March 16, 2005Publication date: February 16, 2006Applicant: FlowMedica, Inc.Inventors: Harry Goodson, Jeffrey Elkins, Samir Patel, Aurelio Valencia, Ricardo Aboytes, Craig Ball, Randy Kesten, Andrew Kramer, Sam Payne, Sophia Pesotchinsky, Michael Rosenthal
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Method and apparatus for selective drug infusion via an intra-aortic flow diverter delivery catheter
Publication number: 20060030814Abstract: A local renal delivery system includes a flow isolation assembly and a local injection assembly. The flow isolation assembly in one mode is adapted to isolate only a partial flow region along the outer circumference along the aorta wall such that fluids inject there are maintained to flow substantially into the renal arteries. Various types of flow isolation assemblies and local injection assemblies are described.Type: ApplicationFiled: March 18, 2005Publication date: February 9, 2006Applicant: FlowMedica, Inc.Inventors: Aurelio Valencia, Ricardo Aboytes, Jeffrey Elkins, Harry Goodson, Samir Patel, Craig Ball, Trevor Greenan, Randy Kesten, Andrew Kramer, Sam Payne, Sophia Pesotchinsky, Michael Rosenthal -
Publication number: 20040064091Abstract: Methods and apparatus are provided for treating congestive heart by actively or passively enhancing perfusion to the renal arteries. A first embodiment comprises a specially configured balloon catheter and extracorporeal pump, wherein the pump operates in a “once-through” fashion or alternating volume displacement mode. In another embodiment the catheter includes a pair of balloons to isolate a region of the aorta, and a third balloon that directs flow into the renal arteries. In still further embodiments, a stent or cuff having a constricted region is deployed in or around the aorta, respectively, to create a backpressure upstream of the stent or cuff. Methods of enhancing renal perfusion also are provided.Type: ApplicationFiled: May 13, 2003Publication date: April 1, 2004Inventors: Gad Keren, Ascher Schmulewitz, Benjamin Spenser, Michael Arad, Randy J. Kesten, Sophia Pesotchinsky, Michael H. Rosenthal, Andrew W. Kramer, Sam G. Payne
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Publication number: 20040064090Abstract: Methods and apparatus are provided for treating congestive heart by actively or passively enhancing perfusion to the renal arteries. A first embodiment comprises a specially configured balloon catheter and extracorporeal pump, wherein the pump operates in a “once-through” fashion or alternating volume displacement mode. In another embodiment the catheter includes a pair of balloons to isolate a region of the aorta, and a third balloon that directs flow into the renal arteries. In still further embodiments, a stent or cuff having a constricted region is deployed in or around the aorta, respectively, to create a backpressure upstream of the stent or cuff. Methods of enhancing renal perfusion also are provided.Type: ApplicationFiled: April 23, 2003Publication date: April 1, 2004Inventors: Gad Keren, Ascher Schmulewitz, Benjamin Spenser, Michael Arad, Randy J. Kesten, Sophia Pesotchinsky, Michael H. Rosenthal, Andrew W. Kramer, Sam G. Payne
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Publication number: 20040064089Abstract: A catheter for delivering a therapeutic or diagnostic agent to a branch blood vessel of a major blood vessel, generally comprising an elongated shaft having at least one lumen in fluid communication with an agent delivery port in a distal section of the shaft, an expandable tubular member on the distal section of the shaft, and a radially expandable member on the tubular member. The tubular member is configured to extend within the blood vessel up-stream and down-stream of a branch vessel, and has an interior passageway which is radially expandable within the blood vessel to separate blood flow through the blood vessel into an outer blood flow stream exterior to the tubular member and an inner blood flow stream within the interior passageway of the tubular member. The radially expandable member is located down-stream of the shaft agent delivery port, and has an expanded configuration with an outer diameter larger than an outer diameter of the tubular member.Type: ApplicationFiled: April 23, 2003Publication date: April 1, 2004Inventors: Randy J. Kesten, Michael H. Rosenthal, Sam G. Payne, Andrew K. Kramer, Sophia Pesotchinsky
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Publication number: 20020169413Abstract: Methods and apparatus are provided for treating congestive heart by actively or passively enhancing perfusion to the renal arteries. A first embodiment comprises a specially configured balloon catheter and extracorporeal pump, wherein the pump operates in a “once-through” fashion or alternating volume displacement mode. In another embodiment the catheter includes a pair of balloons to isolate a region of the aorta, and a third balloon that directs flow into the renal arteries. In still further embodiments, a stent or cuff having a constricted region is deployed in or around the aorta, respectively, to create a backpressure upstream of the stent or cuff. Methods of enhancing renal perfusion also are provided.Type: ApplicationFiled: May 21, 2002Publication date: November 14, 2002Applicant: Libra Medical Systems, Inc.Inventors: Gad Keren, Ascher Shmulewitz, Benjamin Spenser, Michael Arad, Randy J. Kesten, Sophia Pesotchinsky, Michael H. Rosenthal, Andrew W. Kramer, Sam G. Payne
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Patent number: 4915694Abstract: An antimicrobial catheter shield is provided comprising an elastomeric catheter collar and a planar porous elastomeric peripheral flange, with an absorbent patch containing an antimicrobial agent attached to the surface of the flange opposite to the collar. A radial slit extends through the collar, flange and patch and the collar is adapted with a means for securing a catheter to prevent longitudinal motion of the catheter through the collar. The catheter shield provides an antimicrobial patch, as well as a longitudinal and lateral anchor for the catheter, which is easily applied and readily replaced.Type: GrantFiled: October 2, 1987Date of Patent: April 10, 1990Assignee: Vitaphore CorporationInventors: Ronald Yamamoto, Stanley R. Conston, Sophia Pesotchinsky
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Patent number: 4856504Abstract: An antimicrobial orthopedic pin percutaneous protection kit is provided comprising a shield and a pad and patch combination. The shield comprises a central elastomeric collar having a longitudinal orifice and having one end of the collar substantially orthogonally disposed to an elastomeric peripheral flange, the flange extending around the end of the collar, with a radial slit extending through the collar and flange from the longitudinal orifice of the collar to the outer edge of the flange. The shield is adapted with a means for securing the collar around an orthopedic pin to prevent longitudinal motion of the pin. The patch contains an antimicrobial agent and is centrally attached to a porous pad. The pad and patch have a pressure-sensitive adhesive coating on the exposed surfaces.Type: GrantFiled: October 15, 1987Date of Patent: August 15, 1989Assignee: Vitaphore Corp.Inventors: Ronald Yamamoto, Stanley R. Conston, Sophia Pesotchinsky