Patents by Inventor Sophie Vichier-Guerre

Sophie Vichier-Guerre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for obtaining thermostable enzymes, DNA polymerase I variants from having new catalytic activities, methods for obtaining the same, and applications to the same
    Patent number: 8927699
    Abstract: A thermostable mutant DNA polymerase; a method for obtaining the thernmostable mutant DNA polymerase by identifying a thermostable mutant polypeptide exhibiting enzymatic activity, wherein the thermostable mutant polypeptide is a variant of DNA polymerase I obtained from Thermus aquaticus; a polynucleotide, an expression vector, and a host cell encoding the thermostable mutant DNA polymerase; and a method of performing a reverse transcription polymerase chain reaction (RT-PCR) utilizing the thermostable mutant DNA polymerase, as well as a kit for facilitating the same.
    Type: Grant
    Filed: February 25, 2005
    Date of Patent: January 6, 2015
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique (CNRS)
    Inventors: Jean-Luc Jestin, Sophie Vichier-Guerre, Stephane Ferris
  • Methods for obtaining thermostable enzymes, DNA polymerase I variants from having new catalytic activities, methods for obtaining the same, and applications of the same
    Patent number: 7488816
    Abstract: The present invention provides a method for obtaining thermostable enzymes. The present invention also provides variants of DNA polymerase I from Thermus aquaticus. The present invention further provides methods of identifying mutant DNA polymerases having enhanced catalytic activity. The present invention also provides polynucleotides, expression systems, and host cells encoding the mutant DNA polymerases. Still further, the present invention provides a method to carry out reverse transcriptase-polymerase chain reaction (RT-PCR) and kits to facilitate the same.
    Type: Grant
    Filed: February 25, 2005
    Date of Patent: February 10, 2009
    Assignee: Institut Pasteur
    Inventors: Jean-Luc Jestin, Sophie Vichier-Guerre, Stephane Ferris
  • Methods for obtaining thermostable enzymes, DNA polymerase I variants from having new catalytic activities, methods for obtaining the same, and applications of the same
    Patent number: 7417133
    Abstract: The present invention provides a method for obtaining thermostable enzymes. The present invention also provides variants of DNA polymerase I from Thermus aquaticus. The present invention further provides methods of identifying mutant DNA polymerases having enhanced catalytic activity. The present invention also provides polynucleotides, expression systems, and host cells encoding the mutant DNA polymerases. Still further, the present invention provides a method to carry out reverse transcriptase-polymerase chain reaction (RT-PCR) and kits to facilitate the same.
    Type: Grant
    Filed: February 27, 2004
    Date of Patent: August 26, 2008
    Assignee: Institut Pasteur
    Inventors: Jean-Luc Jestin, Sophie Vichier-Guerre
  • Methods for Obtaining Thermostable Enzymes, Dna Polymerase I Variants from Thermus Aquaticus Having New Catalytic Activities, Methods for Obtaining the Same, and Applications to the Same
    Publication number: 20080014609
    Abstract: A thermostable mutant DNA polymerase; a method for obtaining the thernmostable mutant DNA polymerase by identifying a thermostable mutant polypeptide exhibiting enzymatic activity, wherein the thermostable mutant polypeptide is a variant of DNA polymerase I obtained from Thermus aquaticus; a polynucleotide, an expression vector, and a host cell encoding the thermostable mutant DNA polymerase; and a method of performing a reverse transcription polymerase chain reaction (RT-PCR) utilizing the thermostable mutant DNA polymerase, as well as a kit for facilitating the same.
    Type: Application
    Filed: February 25, 2005
    Publication date: January 17, 2008
    Applicants: Institut Pasteur, Centre National De La Recherche Scient. (CNRS)
    Inventors: Jean-Luc Jestin, Sophie Vichier-Guerre, Stephane Ferris
  • Methods for obtaining thermostable enzymes, DNA polymerase I variants from Thermus aquaticus having new catalytic activities, methods for obtaining the same, and applications of the same
    Publication number: 20050250131
    Abstract: The present invention provides a method for obtaining thermostable enzymes. The present invention also provides variants of DNA polymerase I from Thermus aquaticus. The present invention further provides methods of identifying mutant DNA polymerases having enhanced catalytic activity. The present invention also provides polynucleotides, expression systems, and host cells encoding the mutant DNA polymerases. Still further, the present invention provides a method to carry out reverse transcriptase-polymerase chain reaction (RT-PCR) and kits to facilitate the same.
    Type: Application
    Filed: February 25, 2005
    Publication date: November 10, 2005
    Applicant: INSTITUT PASTEUR
    Inventors: Jean-Luc Jestin, Sophie Vichier-Guerre, Stephane Ferris
  • Methods for obtaining thermostable enzymes, DNA polymerase I variants from Thermus aquaticus having new catalytic activities, methods for obtaining the same, and applications of the same
    Publication number: 20050191635
    Abstract: The present invention provides a method for obtaining thermostable enzymes. The present invention also provides variants of DNA polymerase I from Thermus aquaticus. The present invention further provides methods of identifying mutant DNA polymerases having enhanced catalytic activity. The present invention also provides polynucleotides, expression systems, and host cells encoding the mutant DNA polymerases. Still further, the present invention provides a method to carry out reverse transcriptase-polymerase chain reaction (RT-PCR) and kits to facilitate the same.
    Type: Application
    Filed: February 27, 2004
    Publication date: September 1, 2005
    Applicant: INSTITUT PASTEUR
    Inventors: Jean-Luc Jestin, Sophie Vichier-Guerre