Patents by Inventor Soren Nielsen
Soren Nielsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10295442Abstract: The present application provides a two phase immiscible system for the pretreatment of embedded biological samples comprising placing at least one support having an embedded biological sample on its surface into a pretreatment container, adding to the pretreatment container at least one reagent forming a layer, adding a carrier composition to the pretreatment container, such that reagent forming layer is formed on the top of the carrier composition, and in an amount such that the at least one reagent forming layer contacts at least a portion of the embedded biological sample. Pretreatment of the embedded biological samples can include removal of embedding medium from embedded biological, target retrieval and enzyme blocking samples before staining histochemical analysis or other processes. The system also includes an apparatus and processes of automation of the pretreatment methods.Type: GrantFiled: February 28, 2012Date of Patent: May 21, 2019Assignee: DAKO DENMARK A/SInventors: Steen Hauge Matthiesen, Søren Nielsen
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Patent number: 9500014Abstract: The present disclosure includes a hinge assembly for use in a hinged attachment of a panel relative to a frame and providing movement of the panel relative to the frame. A link which provides an extension or reach motion and positioning of the assembly, shown for purposes of illustration and not limitation in the form of a gooseneck arm, is provided in the hinge assembly to facilitate an extended range of motion of the hinge assembly. A first spherical bearing assembly and a second spherical bearing assembly are operatively associated with a bearing end of the link to provide multiple degrees of motion while securely retaining the panel relative to the frame. The hinge is intended to provide universal application of a single version of a hinge which can be used in multiple locations as facilitated by the multiple degrees of motion provided by the bearing end of the link.Type: GrantFiled: October 17, 2013Date of Patent: November 22, 2016Assignee: Hartwell CorporationInventors: Douglas Soren Nielsen, Timothy S. Rozema
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Patent number: 9145982Abstract: The invention relates to a method for renovation and replacement of existing underground pipes and/or the installation of new pipes by using module pipes. The method comprises the step of screwing a second and further module pipe together with the first or consecutive module pipe, if the first or consecutive module pipe has mainly been pushed or pulled into the existing underground pipe.Type: GrantFiled: January 22, 2014Date of Patent: September 29, 2015Assignee: Scandinavian No-Dig Centre ApSInventors: Soren Nielsen, Jesper Nielsen
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Publication number: 20150252602Abstract: The present disclosure includes a hinge assembly for use in a hinged attachment of a panel relative to a frame and providing movement of the panel relative to the frame. A link which provides an extension or reach motion and positioning of the assembly, shown for purposes of illustration and not limitation in the form of a gooseneck arm, is provided in the hinge assembly to facilitate an extended range of motion of the hinge assembly. A first spherical bearing assembly and a second spherical bearing assembly are operatively associated with a bearing end of the link to provide multiple degrees of motion while securely retaining the panel relative to the frame.Type: ApplicationFiled: October 17, 2013Publication date: September 10, 2015Inventors: Douglas Soren Nielsen, Timothy S. Rozema
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Publication number: 20140205382Abstract: The invention relates to a method for renovation and replacement of existing under-ground pipes and/or the installation of new pipes by using module pipes. The method comprises the step of screwing a second and further module pipe together with the first or consecutive module pipe, if the first or consecutive module pipe has mainly been pushed or pulled into the existing underground pipe.Type: ApplicationFiled: January 22, 2014Publication date: July 24, 2014Applicant: Scandinavian No-Dig Centre ApSInventors: Soren Nielsen, Jesper Nielsen
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Publication number: 20140121164Abstract: The present invention relates to a dosage regime of a peptide analogues of [alpha]-melanocyte-stimulating hormone ([alpha]-MSH), which possesses an increased efficacy compared to the native [alpha]-MSH peptide in the treatment or prevention of kidney injury or disease.Type: ApplicationFiled: October 31, 2013Publication date: May 1, 2014Inventors: SOREN NIELSEN, THOMAS ENGELBRECHT NORDKILD JONASSEN, SAMINA KHAN, MARK T. HOUSER, IB BO LUMHOLTZ, MICHAEL BECKERT, THOMAS BEAVER
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Patent number: 8703702Abstract: The invention describes peptide analogues of ?-melanocyte-stimulating hormone (?-MSH), which possess an increased efficacy compared to the native ?-MSH peptide. The ?-MSH analogues exhibit increased anti-inflammatory effects and increased capability to prevent ischemic conditions compared to ?-MSH. The invention further discloses use of the peptides for the manufacture of pharmaceutical compositions for the treatment or prophylaxis of a condition in the tissue of one or more organs of a mammal, and moreover pharmaceutical compositions.Type: GrantFiled: June 3, 2013Date of Patent: April 22, 2014Assignee: AbbVie Inc.Inventors: Thomas E. N. Jonassen, Soren Nielsen, Jorgen Frokiaer, Bjarne Due Larsen
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Publication number: 20140100165Abstract: The present invention relates to a dosage regime of a peptide analogues of [alpha]-melanocyte-stimulating hormone ([alpha]-MSH), which possesses an increased efficacy compared to the native [alpha]-MSH peptide in the treatment or prevention of kidney injury or disease.Type: ApplicationFiled: March 15, 2013Publication date: April 10, 2014Inventors: Soren Nielsen, Thomas Engelbrecht Nordkilk Jonassen, Samina Khan, Mark T. Houser, Ib Bo Lumholtz, Michael Beckert, Thomas Beaver
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Publication number: 20140100162Abstract: The present invention relates to a dosage regime of a peptide analogues of [alpha]-melanocyte-stimulating hormone ([alpha]-MSH), which possesses an increased efficacy compared to the native [alpha]-MSH peptide in the treatment or prevention of kidney injury or disease.Type: ApplicationFiled: June 20, 2013Publication date: April 10, 2014Applicant: AbbVie, Inc.Inventors: Soren Nielsen, Thomas Engelbrecht Nordkild Jonassen, Samina Khan, Mark T. Houser, Ib Bo Lumholtz, Michael Beckert, Thomas Beaver
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Publication number: 20140051118Abstract: The present application provides a two phase immiscible system for the pretreatment of embedded biological samples comprising placing at least one support having an embedded biological sample on its surface into a pretreatment container, adding to the pretreatment container at least one reagent forming a layer, adding a carrier composition to the pretreatment container, such that reagent forming layer is formed on the top of the carrier composition, and in an amount such that the at least one reagent forming layer contacts at least a portion of the embedded biological sample. Pretreatment of the embedded biological samples can include removal of embedding medium from embedded biological, target retrieval and enzyme blocking samples before staining histochemical analysis or other processes. The system also includes an apparatus and processes of automation of the pretreatment methods.Type: ApplicationFiled: February 28, 2012Publication date: February 20, 2014Applicant: Dako Denmark A/SInventors: Steen Hauge Matthiesen, Søren Nielsen
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Patent number: 8563508Abstract: The invention describes peptide analogues of ?-melanocyte-stimulating hormone (?-MSH), which possess an increased efficacy compared to the native ?-MSH peptide. The ?-MSH analogues exhibit increased anti-inflammatory effects and increased capability to prevent ischemic conditions compared to ?-MSH. The invention further discloses use of the peptides for the manufacture of pharmaceutical compositions for the treatment or prophylaxis of a condition in the tissue of one or more organs of a mammal, and moreover pharmaceutical compositions.Type: GrantFiled: March 19, 2013Date of Patent: October 22, 2013Assignee: AbbVie Inc.Inventors: Thomas E. N. Jonassen, Soren Nielsen, Jorgen Frokiaer, Bjarne Due Larsen
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Publication number: 20130252891Abstract: The invention describes peptide analogues of ?-melanocyte-stimulating hormone (?-MSH), which possess an increased efficacy compared to the native ?-MSH peptide. The ?-MSH analogues exhibit increased anti-inflammatory effects and increased capability to prevent ischemic conditions compared to ?-MSH. The invention further discloses use of the peptides for the manufacture of pharmaceutical compositions for the treatment or prophylaxis of a condition in the tissue of one or more organs of a mammal, and moreover pharmaceutical compositions.Type: ApplicationFiled: June 3, 2013Publication date: September 26, 2013Applicant: AbbVie Inc.Inventors: Thomas E.N. JONASSEN, Soren NIELSEN, Jorgen FROKIAER, Bjarne Due LARSEN
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Patent number: 8466104Abstract: The invention describes peptide analogues of a-melanocyte-stimulating hormone (a-MSH), which posses an increased efficacy compared to the native ?-MSH peptide. The ?-MSH analogues exhibit increased anti-inflammatory effects and increased capability to prevent ischemic conditions compared to ?-MSH. The invention further discloses use of the peptides for the manufacture of pharmaceutical compositions for the treatment or prophylaxis of a condition in the tissue of one or more organs of a mammal, and moreover pharmaceutical compositions.Type: GrantFiled: August 26, 2005Date of Patent: June 18, 2013Assignee: AbbVie Inc.Inventors: Thomas E. N. Jonassen, Soren Nielsen, Jorgen Frokiaer, Bjarne Due Larsen
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Patent number: 7673523Abstract: There is described a tubular insert for a magnetic inductive flowmeter, a production method for such a tubular insert and a flowmeter. The tubular insert essentially comprises an electrically-insulating material, in particular, rubber, reinforced with a metal mesh, at least in a measuring section. The tubular metal mesh comprises one or more mesh sections, pre-prepared from sheet mesh by stamping, bending and welding butt edges running essentially parallel to the tube axis such as to form an essentially tubular metal mesh. The tubular metal grid is embedded in the electrically-insulating material passing therethrough and the electrically-insulating material essentially covers the inner and out surfaces of the tubular material. A robust, tubular insert is thus achieved, with a corresponding cheap production cost.Type: GrantFiled: November 10, 2004Date of Patent: March 9, 2010Assignee: Siemens AktiengesellschaftInventor: Søren Nielsen
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Patent number: 7650797Abstract: There is described a tubular insert for a magnetically inductive flowmeter, a production method for said type of tubular insert and a flowmeter. The tubular insert is made of, essentially, an electrically-insulating material, in particular, rubber, which is reinforced by a tubular molding part made of a dimensionally stable plastic which is based on polymers, at least in a measuring section. The tubular molding part is embedded in the electrically-insulating rubber material by a press or casting method such that the electrically-insulating, rubber material essentially covers the inner surfaces of the tubular molding part. An economical to produce, robust, tubular insert is thus achieved.Type: GrantFiled: March 14, 2005Date of Patent: January 26, 2010Assignee: Siemens AktiengesellschaftInventor: Søren Nielsen
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Publication number: 20090069242Abstract: The invention describes peptide analogues of a-melanocyte-stimulating hormone (a-MSH), which posses an increased efficacy compared to the native ?-MSH peptide. The ?-MSH analogues exhibit increased anti-inflammatory effects and increased capability to prevent ischemic conditions compared to ?-MSH. The invention further discloses use of the peptides for the manufacture of pharmaceutical compositions for the treatment or prophylaxis of a condition in the tissue of one or more organs of a mammal, and moreover pharmaceutical compositions.Type: ApplicationFiled: August 26, 2005Publication date: March 12, 2009Applicant: ACTION PHARMA A/SInventors: Thomas E.N. Jonassen, Soren Nielsen, Jorgen Frokiaer, Bjarne Due Larsen
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Publication number: 20080257064Abstract: There is described a tubular insert for a magnetically inductive flowmeter, a production method for said type of tubular insert and a flowmeter. The tubular insert is made of, essentially, an electrically-insulating material, in particular, rubber, which is reinforced by a tubular moulding part made of a dimensionally stable plastic which is based on polymers, at least in a measuring section. The tubular moulding part is embedded in the electrically-insulating rubber material by a press or casting method such that the electrically-insulating, rubber material essentially covers the inner surfaces of the tubular moulding part. An economical to produce, robust, tubular insert is thus achieved.Type: ApplicationFiled: March 14, 2005Publication date: October 23, 2008Inventor: Soren Nielsen
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Patent number: 7415894Abstract: A magnetic inductive flowmeter having a measuring distance that is surrounded by a wall; a magnetic field generating device, and; an electrode device, which has at least one electrode on the inside of the wall and an electrode connection on the outside of the wall. The electrode connection is connected to the electrode by a plug-type connection, and the electrode connection fixes the electrode to the wall.Type: GrantFiled: March 22, 2004Date of Patent: August 26, 2008Assignee: Siemens AktiengesellschaftInventor: Søren Nielsen
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Publication number: 20080196510Abstract: There is described a tubular insert for a magnetic inductive flowmeter, a production method for such a tubular insert and a flowmeter. The tubular insert essentially comprises an electrically-insulating material, in particular, rubber, reinforced with a metal mesh, at least in a measuring section. The tubular metal mesh comprises one or more mesh sections, pre-prepared from sheet mesh by stamping, bending and welding butt edges running essentially parallel to the tube axis such as to form an essentially tubular metal mesh. The tubular metal grid is embedded in the electrically-insulating material passing therethrough and the electrically-insulating material essentially covers the inner and out surfaces of the tubular material. A robust, tubular insert is thus achieved, with a corresponding cheap production cost.Type: ApplicationFiled: November 10, 2004Publication date: August 21, 2008Inventor: Soren Nielsen
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Publication number: 20080031464Abstract: Method of evaluating perception intensity of an audio input signal (IS) comprising the steps of receiving the audio input signal (IS), estimating a time variant distribution function (TVDF) on the basis of said audio input signal (IS) or a derivative thereof, determining the perception intensity as at least one perception intensity estimate (PIE) on the basis of said estimated time variant distribution function (TVDF). According to the invention perception intensity has been obtained on the basis of a time variant distribution function. Thereby, an advantageous universal and flexible determination of perception intensity is obtained. The universal applicability is basically obtained due to the fact that a distribution function may match and describe audio input signal of very different nature. Thus, according to the invention even speech, music and noise may be evaluated on the basis of a distribution function.Type: ApplicationFiled: June 25, 2004Publication date: February 7, 2008Applicant: TC ELECTRONIC A/SInventors: Søren Nielsen, Esben Skovenborg