Patents by Inventor Soren Peter Olesen

Soren Peter Olesen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ERG CHANNEL OPENERS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS
    Publication number: 20110071164
    Abstract: This invention relates to the use of ERG channel openers for the treatment of cardiac arrhythmias, and to the use of specific compounds for such treatment. In a separate aspect the invention provides novel compounds useful as ERG channel openers.
    Type: Application
    Filed: November 9, 2010
    Publication date: March 24, 2011
    Inventors: Søren Peter OLESEN, Morten Grunnet, Palle Christophersen, Dorte STRØBÆK, Joachim Demnitz, Rie S. Hansen
  • ERG channel openers for the treatment of cardiac arrhythmias
    Patent number: 7851492
    Abstract: This invention relates to the use of ERG channel openers for the treatment of cardiac arrhythmias, and to the use of specific compounds for such treatment. In a separate aspect the invention provides novel compounds useful as ERG channel openers.
    Type: Grant
    Filed: September 6, 2004
    Date of Patent: December 14, 2010
    Assignee: Neurosearch A/S
    Inventors: Søren Peter Olesen, Morten Grunnet, Palle Christophersen, Dorte Strøbæk, Joachim Demnitz, Rie S. Hansen
  • Benzimidazol-2-one derivatives and their use
    Patent number: 7244756
    Abstract: Certain 1,5-disubstituted benzimidazol-2-one compounds useful as therapeutic agents. The compounds may be of the Formula I wherein: R? represents hydrogen or alkyl; R? represents halogen or trihalogenmethyl; and Hlg represents halogen; provided, however, that if Hlg is F, then R? is not Cl. Also, use of the 1,5-disubstituted benzimidazol-2-one compounds, or pharmaceutically-acceptable addition salts thereof, in applications that benefit from increasing the blood-brain barrier permeability.
    Type: Grant
    Filed: June 17, 2003
    Date of Patent: July 17, 2007
    Assignee: Poseidon Pharmaceuticals A/S
    Inventors: Lars Siim Madsen, Camilla ærteberg Bæk, Annette Lauridsen, Søren Peter Olesen
  • Use of isatin derivatives as ion channel activating agents
    Patent number: 6969729
    Abstract: The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SKCa and IKCa channels. In further aspects, the present invention relates to the use of these SK/IK channel activating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK channel activating agents.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: November 29, 2005
    Assignee: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Tino Dyhring Jørgensen, Philip K. Ahring, Palle Christophersen, Dorte Strøbaek, Lene Teuber, Søren Peter Olesen
  • Potassium channel blocking agents
    Patent number: 6878701
    Abstract: Compounds of Formula I: wherein A and B are linking groups; R1, R2, R3 and R4 are defined moieties. An exemplary compound is: These compounds function as potassium channel blocking agents, and can be used in a wide variety of pharmaceutical compositions for the treatment of a wide variety of diseases.
    Type: Grant
    Filed: December 28, 2001
    Date of Patent: April 12, 2005
    Assignee: Neurosearch A/S
    Inventors: Lene Teuber, Soren Peter Olesen, Dorte Strobaek
  • Ion channel modulating agents
    Patent number: 6759422
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds represented by general formula (I) that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: July 6, 2004
    Assignee: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Substrate and a method for determining and/or monitoring electrophysiological properties of ion channels
    Publication number: 20040055901
    Abstract: The present invention relates to a substrate and a method for obtaining an electrophysiological measuring configuration in which a cell forms a high resistive seal (giga-seal) around a measuring electrode making it suitable for determining and monitoring a current flow through the cell membrane. The substrate is typically part of an apparatus for studying electrical events in cell membranes, such as an apparatus for carrying out patch clamp techniques utilised to study ion transfer channels in biological membranes. The substrate has a plurality or an array of measuring sites with integrated measuring and reference electrodes formed by wafer processing technology. The electrodes are adapted to conduct a current between them by delivery of ions by one electrode and receipt of ions by the other electrode and are typically silver/silver halide electrodes.
    Type: Application
    Filed: October 23, 2003
    Publication date: March 25, 2004
    Applicant: Sophion Bioscience A/S
    Inventors: Jon Wulff Petersen, Pieter Telleman, Ole Hansen, Palle Christophersen, Morten Bech, Soren Peter Olesen, Jorgen Due, Lars Thomsen
  • Substrate and a method for determining and/or monitoring electrophysiological properties of ion channels
    Patent number: 6682649
    Abstract: The present invention relates to a substrate and a method for obtaining an electrophysiological measuring configuration in which a cell forms a high resistive seal (giga-seal) around a measuring electrode making it suitable for determining and monitoring a current flow through the cell membrane. The substrate is typically part of an apparatus for studying electrical events in cell membranes, such as an apparatus for carrying out patch clamp techniques utilised to study ion transfer channels in biological membranes. The substrate has a plurality or an array of measuring sites with integrated measuring and reference electrodes formed by wafer processing technology. The electrodes are adapted to conduct a current between them by delivery of ions by one electrode and receipt of ions by the other electrode and are typically silver/silver halide electrodes.
    Type: Grant
    Filed: October 2, 2000
    Date of Patent: January 27, 2004
    Assignee: Sophion Bioscience A/S
    Inventors: Jon Wulff Petersen, Pieter Telleman, Ole Hansen, Palle Christophersen, Morten Bech, Soren Peter Olesen, Jorgen Due, Lars Thomsen
  • Use of 3-substituted oxindole derivatives as kcnq potassium channel modulators
    Publication number: 20030181507
    Abstract: The present invention relates to a novel method of treating of pain or anxiety, using compounds that modulate KCNQ potassium channels and currents.
    Type: Application
    Filed: February 24, 2003
    Publication date: September 25, 2003
    Inventors: Bo Skaaning Jensen, Rikke Schroder, Dorte Strobaek, Soren Peter Olesen
  • Use of isatin derivatives as ion channel activating agents
    Publication number: 20030114513
    Abstract: The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SKCa and IKCa channels. In further aspects, the present invention relates to the use of these SK/IK channel activating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK channel activating agents.
    Type: Application
    Filed: October 16, 2002
    Publication date: June 19, 2003
    Applicant: NeuroSearch A/S
    Inventors: Bo Skaaning Jensen, Tino Dyhring Jorgensen, Philip K. Ahring, Palle Christophersen, Dorte Strobaek, Lene Teuber, Soren Peter Olesen
  • Bis(benzimidazole) derivatives serving as potassium blocking agents
    Patent number: 6569880
    Abstract: This invention relates to novel potassium channel blocking agents, and their use in the preparation of pharmaceutical compositions.
    Type: Grant
    Filed: February 28, 2002
    Date of Patent: May 27, 2003
    Assignee: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Søren Peter Olesen, Lene Teuber, Dan Peters, Dorte Strøbæk
  • Use of ion channel modulating agents
    Patent number: 6525043
    Abstract: The present invention relates to the use of a particular class of chemical compounds as modulators of SKCa, IKCa and BKCa channels, and to pharmaceutical compositions comprising the SK/IK/BK channel modulating agents.
    Type: Grant
    Filed: October 25, 2001
    Date of Patent: February 25, 2003
    Assignee: NeuroSearch A/S
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Ion channel modulating agents
    Publication number: 20030008906
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds represented by general formula (I) that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Application
    Filed: August 2, 2002
    Publication date: January 9, 2003
    Applicant: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Automatic electrode positioning apparatus
    Patent number: 6470226
    Abstract: The present invention relates to an automatic electrode position apparatus for connecting an electrode to a cell. The invention further provides methods for utilizing the apparatus of the invention. Apparatus and methods are described for studying electrical activities in cell membranes. These methods are especially useful in large scale screening programs in the pharmaceutical industry.
    Type: Grant
    Filed: September 21, 1999
    Date of Patent: October 22, 2002
    Assignee: Sophion Bioscience A/S
    Inventors: Soren-Peter Olesen, Palle Christophersen, Morten Bech
  • Potassium channel blocking agents
    Publication number: 20020137784
    Abstract: This invention relates to novel potassium channel blocking agents, and their use in the preparation of pharmaceutical compositions.
    Type: Application
    Filed: February 28, 2002
    Publication date: September 26, 2002
    Applicant: NeuroSearch A/S
    Inventors: Bo Skaaning Jensen, Soren Peter Olesen, Lene Teuber, Dan Peters, Dorte Strobaek
  • Potassium channel blocking agents
    Publication number: 20020128279
    Abstract: This invention relates to novel potassium channel blocking agents, and their use in the preparation of pharmaceutical compositions.
    Type: Application
    Filed: December 28, 2001
    Publication date: September 12, 2002
    Inventors: Lene Teuber, Soren Peter Olesen, Dorte Strobaek
  • Ion channel modulating agents
    Publication number: 20020065315
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds represented by general Formula (I) and a pharmaceutically acceptable salt or an oxide or a hydrate thereof, that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Application
    Filed: November 9, 2001
    Publication date: May 30, 2002
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Use of ion channel modulating agents
    Publication number: 20020065266
    Abstract: The present invention relates to the use of a particular class of chemical compounds as modulators of SKCa, IKCa and BKCa channels, and to pharmaceutical compositions comprising the SK/IK/BK channel modulating agents.
    Type: Application
    Filed: October 25, 2001
    Publication date: May 30, 2002
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Ion channel modulating agents
    Publication number: 20020061914
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds represented by general formula (I) that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Application
    Filed: November 9, 2001
    Publication date: May 23, 2002
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Potassium channel blocking agents
    Patent number: 6380180
    Abstract: This invention relates to novel potassium channel blocking agents, and their use in the preparation of pharmaceutical compositions.
    Type: Grant
    Filed: December 29, 2000
    Date of Patent: April 30, 2002
    Assignee: NeuroSearch A/S
    Inventors: Bo Skaaning Jensen, Søren Peter Olesen, Lene Teuber, Dan Peters, Dorte Strøbaek