Patents by Inventor Spencer ALFORD

Spencer ALFORD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240091268
    Abstract: The present application provides methods and processes for pharmaceutical formulations comprising mesenchymal stem cell secretome for use in ocular treatments, as well as methods for manufacturing and packaging such formulations.
    Type: Application
    Filed: September 6, 2023
    Publication date: March 21, 2024
    Inventors: Spencer Alford, Felix Santhosh Francis
  • Patent number: 11919942
    Abstract: The present application provides methods and processes for making and using a fibronectin composition, as well as methods for treating ocular conditions and/or disorders with the cellular fibronectin composition described herein.
    Type: Grant
    Filed: August 11, 2023
    Date of Patent: March 5, 2024
    Assignee: COMBANGIO, INC.
    Inventors: Spencer Alford, Audrey Smith
  • Patent number: 11891428
    Abstract: The present application provides methods and processes for making and using a fibronectin composition, as well as methods for treating ocular conditions and/or disorders with the cellular fibronectin composition described herein.
    Type: Grant
    Filed: July 8, 2022
    Date of Patent: February 6, 2024
    Assignee: COMBANGIO, INC.
    Inventors: Spencer Alford, Audrey Smith
  • Publication number: 20240033297
    Abstract: The present application provides methods and processes for making and using a mesenchymal stem cell secretome, as well as methods for treating ocular conditions and/disorders with the mesenchymal stem cell secretome described herein.
    Type: Application
    Filed: April 17, 2023
    Publication date: February 1, 2024
    Inventor: Spencer Alford
  • Publication number: 20240012011
    Abstract: The present application provides methods and assays for assessing a mesenchymal stem cell secretome in order to use the MSC secretome in methods of treating ocular conditions and/disorders.
    Type: Application
    Filed: July 7, 2023
    Publication date: January 11, 2024
    Inventors: Spencer Alford, Peter Baciu
  • Publication number: 20230391847
    Abstract: The present application provides methods and processes for making and using a fibronectin composition, as well as methods for treating ocular conditions and/or disorders with the cellular fibronectin composition described herein.
    Type: Application
    Filed: August 11, 2023
    Publication date: December 7, 2023
    Inventors: Spencer Alford, Audrey Smith
  • Patent number: 11654160
    Abstract: The present application provides methods and processes for making and using a mesenchymal stem cell secretome, as well as methods for treating ocular conditions and/disorders with the mesenchymal stem cell secretome described herein.
    Type: Grant
    Filed: April 7, 2020
    Date of Patent: May 23, 2023
    Assignee: COMBANGIO, INC.
    Inventor: Spencer Alford
  • Publication number: 20230000954
    Abstract: The present application provides methods and processes for making and using a fibronectin composition, as well as methods for treating ocular conditions and/or disorders with the cellular fibronectin composition described herein.
    Type: Application
    Filed: July 1, 2022
    Publication date: January 5, 2023
    Inventors: Spencer ALFORD, Audrey Smith
  • Publication number: 20230002476
    Abstract: The present application provides methods and processes for making and using a fibronectin composition, as well as methods for treating ocular conditions and/or disorders with the cellular fibronectin composition described herein.
    Type: Application
    Filed: July 8, 2022
    Publication date: January 5, 2023
    Inventors: Spencer Alford, Audrey Smith
  • Publication number: 20210369617
    Abstract: The present application provides methods and processes for making and using a lyophilized mesenchymal stem cell secretome, as well as methods for treating ocular conditions and/disorders with the reconstituted lyophilized mesenchymal stem cell secretome described herein.
    Type: Application
    Filed: April 6, 2021
    Publication date: December 2, 2021
    Inventor: Spencer ALFORD
  • Patent number: 11129853
    Abstract: The present application provides methods and processes for making and using a mesenchymal stem cell secretome, as well as methods for treating ocular conditions and/disorders with the mesenchymal stem cell secretome described herein.
    Type: Grant
    Filed: February 25, 2021
    Date of Patent: September 28, 2021
    Assignee: COMBANGIO, INC.
    Inventor: Spencer Alford
  • Publication number: 20210187034
    Abstract: The present application provides methods and processes for making and using a mesenchymal stem cell secretome, as well as methods for treating ocular conditions and/disorders with the mesenchymal stem cell secretome described herein.
    Type: Application
    Filed: February 25, 2021
    Publication date: June 24, 2021
    Inventor: Spencer ALFORD
  • Publication number: 20210052656
    Abstract: The present application provides methods and processes for making and using a mesenchymal stem cell secretome, as well as methods for treating ocular conditions and/disorders with the mesenchymal stem cell secretome described herein.
    Type: Application
    Filed: April 7, 2020
    Publication date: February 25, 2021
    Inventor: Spencer ALFORD
  • Patent number: 10881693
    Abstract: The present application provides methods and processes for making and using a mesenchymal stem cell secretome, as well as methods for treating ocular conditions and/disorders with the mesenchymal stem cell secretome described herein.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: January 5, 2021
    Assignee: COMBANGIO, INC.
    Inventor: Spencer Alford
  • Publication number: 20200325452
    Abstract: The present application provides methods and processes for making and using a mesenchymal stem cell secretome, as well as methods for treating ocular conditions and/disorders with the mesenchymal stem cell secretome described herein.
    Type: Application
    Filed: February 7, 2020
    Publication date: October 15, 2020
    Inventor: Spencer ALFORD
  • Patent number: 10758571
    Abstract: The present application provides methods and processes for making and using a mesenchymal stem cell secretome, as well as methods for treating ocular conditions and/disorders with the mesenchymal stem cell secretome described herein.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: September 1, 2020
    Assignee: COMBANGIO, INC.
    Inventor: Spencer Alford
  • Publication number: 20180209968
    Abstract: A novel assay for determining a molecular process using a fluorescent protein exchange assay, and a composition for use thereof, are provided. The assay provides first and second signalling proteins and an exchange protein, wherein the exchange protein interacts with the first signalling protein to form a complex, then introducing the second signalling protein, wherein in response to the molecular process, the exchange protein dissociates from the first protein and associates with the second protein. The change in signal in response to the exchange of the proteins is measured to indicate a molecular process.
    Type: Application
    Filed: March 21, 2018
    Publication date: July 26, 2018
    Inventors: Robert E. CAMPBELL, Yidan DING, Spencer ALFORD, John ENTERINA, Tiffany Yan LAI
  • Patent number: 9970930
    Abstract: A novel assay for determining a molecular process using a fluorescent protein exchange assay, and a composition for use thereof, are provided. The assay provides first and second signalling proteins and an exchange protein, wherein the exchange protein interacts with the first signalling protein to form a complex, then introducing the second signalling protein, wherein in response to the molecular process, the exchange protein dissociates from the first protein and associates with the second protein. The change in signal in response to the exchange of the proteins is measured to indicate a molecular process.
    Type: Grant
    Filed: May 6, 2015
    Date of Patent: May 15, 2018
    Assignee: The Governors of the University of Alberta
    Inventors: Robert E. Campbell, Yidan Ding, Spencer Alford, Jhon Ralph Enterina, Tiffany Yan Lai
  • Publication number: 20150323544
    Abstract: A novel assay for determining a molecular process using a fluorescent protein exchange assay, and a composition for use thereof, are provided. The assay provides first and second signalling proteins and an exchange protein, wherein the exchange protein interacts with the first signalling protein to form a complex, then introducing the second signalling protein, wherein in response to the molecular process, the exchange protein dissociates from the first protein and associates with the second protein. The change in signal in response to the exchange of the proteins is measured to indicate a molecular process.
    Type: Application
    Filed: May 6, 2015
    Publication date: November 12, 2015
    Inventors: Robert E. CAMPBELL, Yidan DING, Spencer ALFORD, Jhon Ralph ENTERINA, Tiffany Yan LAI