Patents by Inventor Spencer David Kimball

Spencer David Kimball has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMPOUNDS AND THERAPEUTIC METHODS
    Publication number: 20220185827
    Abstract: The invention provides a complex comprising Zn2+ and a compound of formula (I): or a deuterated analog thereof, or an ion or poly-ion thereof, or a salt thereof that is useful for treating cancer, as well as compositions and kits comprising such complexes.
    Type: Application
    Filed: April 22, 2020
    Publication date: June 16, 2022
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Spencer David KIMBALL, Darren R. CARPIZO, John A. GILLERAN
  • PHARMACEUTICAL COMPOUNDS AND THERAPEUTIC METHODS
    Publication number: 20220096492
    Abstract: The invention provides a complex comprising Zn2+ and a compound of formula (I): or a deuterated analog thereof, or an ion or poly-ion thereof, or a salt thereof that is useful for treating cancer, as well as compositions and kits comprising such complexes.
    Type: Application
    Filed: April 22, 2020
    Publication date: March 31, 2022
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Spencer David KIMBALL, Darren R. CARPIZO, John A. GILLERAN
  • Hydrazone derivatives for the treatment of cancer
    Patent number: 10828288
    Abstract: The invention provides compounds of formula (I): and salts thereof wherein ring A, R2, HET, X, n, and R3 have any of the meanings described in the specification, as well as compositions comprising such compounds and salts, and methods for treating cancer using such compounds and salts.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: November 10, 2020
    Assignees: Rutgers, the State University of New Jersey, The Research Foundation for the State University of New York
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • Zinc complexes of hydrazones and (thio)semicarbazones and their use for the treatment of cancer
    Patent number: 10729671
    Abstract: The invention provides complexes of Zn2+ of formulae (la) and (IIa) that are useful for treating cancer, as well as compositions and kits comprising such complexes.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: August 4, 2020
    Assignees: Rutgers, the State University of New Jersey, The Research Foundation for the State University of New York
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • (Thio, oxo and seleno) semicarbazone complexes with zinc and their use for treating cancer
    Patent number: 10604481
    Abstract: The invention provides organic complexes of Zn2+ that are useful for treating cancer, as well as compositions and kits comprising such complexes, and intermediate monomer compounds that are useful for the preparation of such complexes.
    Type: Grant
    Filed: January 21, 2019
    Date of Patent: March 31, 2020
    Assignees: Rutgers, The State University of New Jersey, The Research Foundation for the State University of New York
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • (Thio, oxo, and seleno) semicarbazone derivatives and their use for treating cancer
    Patent number: 10604480
    Abstract: The invention provides compounds of formula I and II and salts thereof, wherein R1, R2, Y, R3, and R4 have any of the meanings described in the specification, as well as compositions comprising such compounds and salts, and methods for treating cancer using such compounds and salts.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: March 31, 2020
    Assignees: Rutgers, The State University of New Jersey, The Research Foundation for the State University of New York
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • (THIO, OXO AND SELENO) SEMICARBAZONE COMPLEXES WITH ZINC AND THEIR USE FOR TREATING CANCER
    Publication number: 20190256460
    Abstract: The invention provides organic complexes of Zn2+ that are useful for treating cancer, as well as compositions and kits comprising such complexes, and intermediate monomer compounds that are useful for the preparation of such complexes.
    Type: Application
    Filed: January 21, 2019
    Publication date: August 22, 2019
    Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • SODIUM GLUCOSE CO-TRANSPORTER INHIBITORS AND METHODS OF THEIR USE
    Publication number: 20190099436
    Abstract: Sulfanyl-tetrahydropyran-based compounds, pharmaceutical compositions comprising them, and methods of their use for the treatment of diseases and disorders such as diabetes and obesity are disclosed.
    Type: Application
    Filed: March 27, 2018
    Publication date: April 4, 2019
    Inventors: Bryce Alden HARRISON, Spencer David KIMBALL, Ross MABON, David Brent RAWLINS
  • (Thio, oxo, and seleno) semicarbazone complexes with zinc and their use for treating cancer
    Patent number: 10221133
    Abstract: The invention provides organic complexes of Zn2+ of formula (I) that are useful for treating cancer, as well as compositions and kits comprising such complexes, and intermediate monomer compounds that are useful for the preparation of such complexes.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: March 5, 2019
    Assignees: Rutgers, The State University of New Jersey, The Research Foundation for the State University of New York
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO TRPA1
    Publication number: 20180051020
    Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.
    Type: Application
    Filed: October 28, 2016
    Publication date: February 22, 2018
    Inventors: Xinyuan Wu, Spencer David Kimball, Ping Chen, Ding Zhou, Shaoping Peng
  • ZINC COMPLEXES OF HYDRAZONES AND (THIO)SEMICARBAZONES AND THEIR USE FOR THE TREATMENT OF CANCER
    Publication number: 20180000772
    Abstract: The invention provides complexes of Zn2+ of formulae (la) and (IIa) that are useful for treating cancer, as well as compositions and kits comprising such complexes.
    Type: Application
    Filed: January 27, 2016
    Publication date: January 4, 2018
    Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY O F NEW YORK
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • (THIO, OXO, AND SELENO) SEMICARBAZONE DERIVATIVES AND THEIR USE FOR TREATING CANCER
    Publication number: 20180002280
    Abstract: The invention provides compounds of formula I and II and salts thereof, wherein R1, R2, Y, R3, and R4 have any of the meanings described in the specification, as well as compositions comprising such compounds and salts, and methods for treating cancer using such compounds and salts.
    Type: Application
    Filed: January 27, 2016
    Publication date: January 4, 2018
    Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • HYDRAZONE DERIVATIVES FOR THE TREATMENT OF CANCER
    Publication number: 20180000806
    Abstract: The invention provides compounds of formula (I): and salts thereof wherein ring A, R2, HET, X, n, and R3 have any of the meanings described in the specification, as well as compositions comprising such compounds and salts, and methods for treating cancer using such compounds and salts.
    Type: Application
    Filed: January 27, 2016
    Publication date: January 4, 2018
    Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • (THIO, OXO, AND SELENO) SEMICARBAZONE COMPLEXES WITH ZINC AND THEIR USE FOR TREATING CANCER
    Publication number: 20180002279
    Abstract: The invention provides organic complexes of Zn2+ of formula (I) that are useful for treating cancer, as well as compositions and kits comprising such complexes, and intermediate monomer compounds that are useful for the preparation of such complexes.
    Type: Application
    Filed: January 27, 2016
    Publication date: January 4, 2018
    Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • SODIUM GLUCOSE CO-TRANSPORTER INHIBITORS AND METHODS OF THEIR USE
    Publication number: 20170087172
    Abstract: Sulfanyl-tetrahydropyran-based compounds, pharmaceutical compositions comprising them, and methods of their use for the treatment of diseases and disorders such as diabetes and obesity are disclosed.
    Type: Application
    Filed: May 16, 2016
    Publication date: March 30, 2017
    Inventors: Bryce Alden HARRISON, Spencer David KIMBALL, Ross MABON, David Brent RAWLINS
  • Compounds useful for treating disorders related to TRPA1
    Patent number: 9505756
    Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: November 29, 2016
    Assignee: HYDRA BIOSCIENCES, INC.
    Inventors: Xinyuan Wu, Spencer David Kimball, Ping Chen, Ding Zhou, Shaoping Peng
  • Sodium glucose co-transporter inhibitors and methods of their use
    Patent number: 9365602
    Abstract: Sulfanyl-tetrahydropyran-based compounds, pharmaceutical compositions comprising them, and methods of their use for the treatment of diseases and disorders such as diabetes and obesity are disclosed.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: June 14, 2016
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Bryce Alden Harrison, Spencer David Kimball, Ross Mabon, David Brent Rawlins
  • SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF
    Publication number: 20160145257
    Abstract: Compounds, compositions and methods are described for inhibiting the TRPC5 ion channel and disorders related to TRPC5.
    Type: Application
    Filed: January 30, 2016
    Publication date: May 26, 2016
    Inventors: Bertrand L. Chenard, Randall J. Gallaschun, Spencer David Kimball
  • COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO TRPA1
    Publication number: 20160009708
    Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.
    Type: Application
    Filed: February 6, 2015
    Publication date: January 14, 2016
    Applicant: HYDRA BIOSCIENCES, INC.
    Inventors: Xinyuan Wu, Spencer David Kimball, Ping Chen, Ding Zhou, Shaoping Peng
  • COMPOUNDS USEFUL FOR TREATING INJURIES FROM WARFARE AGENTS
    Publication number: 20150352115
    Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.
    Type: Application
    Filed: December 22, 2014
    Publication date: December 10, 2015
    Applicant: HYDRA BIOSCIENCES, INC.
    Inventors: Xinyuan Wu, Spencer David Kimball