Patents by Inventor Sri Harsha Tummala

Sri Harsha Tummala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODRUGS OF TREPROSTINIL
    Publication number: 20240058287
    Abstract: Provided are novel treprostinil based compounds, methods of treatment using the same, and their methods of making.
    Type: Application
    Filed: October 17, 2023
    Publication date: February 22, 2024
    Applicants: United Therapeutics Corporation, MannKind Corporation
    Inventors: Hitesh BATRA, Liang GUO, Patrick POISSON, Sri Harsha TUMMALA, Elizabeth Ann HARRIS
  • RALINEPAG PRODRUGS AND USES THEREOF
    Publication number: 20240002334
    Abstract: Described herein are ralinepag prodrugs, as well as pharmaceutical compositions thereof, and methods of use thereof in the treatment of diseases or conditions that would benefit from treatment with a prostacyclin (IP) receptor agonist compound, such as but not limited to pulmonary hypertension (PH) diseases.
    Type: Application
    Filed: March 17, 2023
    Publication date: January 4, 2024
    Inventors: Hitesh BATRA, Patrick POISSON, Liang GUO, Susovan JANA, Sri Harsha TUMMALA
  • Prodrugs of treprosiinil
    Patent number: 11793780
    Abstract: Provided are novel treprostinil based compounds, methods of treatment using the same, and their methods of making.
    Type: Grant
    Filed: June 8, 2021
    Date of Patent: October 24, 2023
    Assignees: United Therapeutics Corporation, Mann Kind Corporation
    Inventors: Hitesh Batra, Liang Guo, Patrick Poisson, Sri Harsha Tummala, Elizabeth Ann Harris
  • PRODRUGS OF TREPROSTINIL
    Publication number: 20210378996
    Abstract: Provided are novel treprostinil based compounds, methods of treatment using the same, and their methods of making.
    Type: Application
    Filed: June 8, 2021
    Publication date: December 9, 2021
    Applicants: United Therapeutics Corporation, MannKind Corporation
    Inventors: Hitesh BATRA, Liang GUO, Patrick POISSON, Sri Harsha TUMMALA, Elizabeth Ann HARRIS
  • Methods for producing Beraprost and its derivatives
    Patent number: 10640481
    Abstract: The present invention is directed to methods for preparing Beraprost and novel synthetic intermediates for Beraprost.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: May 5, 2020
    Assignee: Lung Biotechnology PBC
    Inventors: Hitesh Batra, Sudersan M. Tuladhar, Sri Harsha Tummala, Raju Penmasta, David A. Walsh
  • METHODS FOR PRODUCING BERAPROST AND ITS DERIVATIVES
    Publication number: 20190202797
    Abstract: The present invention is directed to methods for preparing Beraprost and novel synthetic intermediates for Beraprost.
    Type: Application
    Filed: March 11, 2019
    Publication date: July 4, 2019
    Applicant: Lung Biotechnology PBC
    Inventors: Hitesh Batra, Sudersan M. Tuladhar, Sri Harsha Tummala, Raju Penmasta, David A. Walsh
  • Methods for producing Beraprost and its derivatives
    Patent number: 10246430
    Abstract: The present invention is directed to methods for preparing Beraprost and novel synthetic intermediates for Beraprost.
    Type: Grant
    Filed: May 4, 2018
    Date of Patent: April 2, 2019
    Assignee: Lung Biotechnology PBC
    Inventors: Hitesh Batra, Sudersan M. Tuladhar, Sri Harsha Tummala, Raju Penmasta, David A. Walsh
  • Methods for producing beraprost and its derivatives
    Patent number: 10005753
    Abstract: The present invention is directed to methods for preparing Beraprost and novel synthetic intermediates for Beraprost. In one aspect, a process is provided to produce a pharmaceutical compound represented by the general Formula (I) via a radical cyclization route. The process is completed in fewer steps than the known synthetic methods and may be conducted to prepare commercially useful quantities. In another aspect, synthetic methods are provided for producing Beraprost and its derivatives, which are stereoselective, efficient, scalable and economical. In another aspect, substantially isomerically pure compounds and intermediates are produced by the above processes.
    Type: Grant
    Filed: May 19, 2015
    Date of Patent: June 26, 2018
    Assignee: Lung Biotechnology PBC
    Inventors: Hitesh Batra, Sudersan M. Tuladhar, Sri Harsha Tummala, Raju Penmasta, David A. Walsh
  • METHODS FOR PRODUCING BERAPROST AND ITS DERIVATIVES
    Publication number: 20170166545
    Abstract: The present invention is directed to methods for preparing Beraprost and novel synthetic intermediates for Beraprost. In one aspect, a process is provided to produce a pharmaceutical compound represented by the general Formula (I) via a radical cyclization route. The process is completed in fewer steps than the known synthetic methods and may be conducted to prepare commercially useful quantities. In another aspect, synthetic methods are provided for producing Beraprost and its derivatives, which are stereoselective, efficient, scalable and economical. In another aspect, substantially isomerically pure compounds and intermediates are produced by the above processes.
    Type: Application
    Filed: May 19, 2015
    Publication date: June 15, 2017
    Applicant: Lung Biotechnology PBC
    Inventors: Hitesh Batra, Sudersan M. Tuladhar, Sri Harsha Tummala, Raju Penmasta, David A. Walsh