Abstract: A method to increase the efficiency of myotube generation and maturation from pluripotent stem cells comprising: (a) differentiating pluripotent stem cells to myogenic progenitors; and (b) terminally differentiating said myogenic progenitors from (a) into myotubes in the presence of at least one gamma secretase inhibitor, wherein myotube generation is increased in the presence of at least one gamma secretase inhibitor, as compared to differentiation in the absence of gamma secretase inhibitors.

Abstract: A method to increase the efficiency of myotube generation and maturation from pluripotent stem cells comprising: (a) differentiating pluripotent stem cells to myogenic progenitors; and (b) terminally differentiating said myogenic progenitors from (a) p into myotubes in the presence of at least one gamma secretase inhibitor, wherein myotube generation is increased in the presence of at least one gamma secretase inhibitor, as compared to differentiation in the absence of gamma secretase inhibitors.

Abstract: A connecting device having current rails (8-12) that produce an electrical connection between the stator winding and associated contact sites (35-39) of an electrical control device (6) of an electrical machine (1), the electrical control device being provided for controlling the stator winding, wherein the connecting device (5) comprises current rails (8-12) that protrude at the stator winding ends (18-22) in a parallel manner with respect to the middle axis of the electrical machine (1) and the current rails (8-12) lie in guide channels (32-34) that are arranged on a connection plate (31) that is embodied from an electrically non-conductive material.