Patents by Inventor Sriram Venkataramani
Sriram Venkataramani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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ALCOHOL-RESISTANT SILICONIZED POLYCARBONATE POLYURETHANES AND MEDICAL DEVICES INCORPORATING THE SAME
Publication number: 20230399454Abstract: A catheter can include an extruded shaft that includes a lumen extending from a proximal end to a distal end and a sidewall that defines at least a portion of the lumen, the sidewall includes a siliconized polycarbonate polyurethane of a specified formulation. Due to the formulation, the sidewall can be alcohol resistant, which can, in some instances, permit alcohol locking of the catheter.Type: ApplicationFiled: August 24, 2023Publication date: December 14, 2023Applicant: Piper Access, LLCInventors: Jay Allen Muse, Nathaniel J. Fredin, Sriram Venkataramani -
Alcohol-resistant siliconized polycarbonate polyurethanes and medical devices incorporating the same
Patent number: 11746181Abstract: An alcohol-resistant siliconized polycarbonate polyurethane can include a soft segment and a hard segment. The soft segment can include a polycarbonate polyol and a polysiloxane, which can be present in an amount less than the polycarbonate polyol. The hard segment can include an isocyanate and a chain extender. Peripherally inserted central catheter (PICC) devices can include one or more components that are at least partially formed from one or more formulations of the siliconized polycarbonate polyurethane catheter. The PICC devices can withstand alcohol locking, and can be power injectable both before and after alcohol locking events.Type: GrantFiled: November 19, 2018Date of Patent: September 5, 2023Assignee: Piper Access, LLCInventors: Jay Allen Muse, Nathaniel J. Fredin, Sriram Venkataramani -
Patent number: 10730994Abstract: The present invention provides silicon-based polycarbonates, processes for their preparation and their use in the synthesis of copolymers, in particular segmented copolymers such as polyurethanes for biomedical applications.Type: GrantFiled: June 8, 2016Date of Patent: August 4, 2020Assignee: Aortech International plcInventors: Francis P. Maguire, Sriram Venkataramani
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Patent number: 10655012Abstract: The present invention provides silicon-based polycarbonates, processes for their preparation and their use in the synthesis of copolymers, in particular segmented copolymers such as polyurethanes for biomedical applications.Type: GrantFiled: June 8, 2016Date of Patent: May 19, 2020Assignee: Aortech International plcInventors: Francis P. Maguire, Sriram Venkataramani
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Patent number: 10597497Abstract: The present invention relates to biostable gel comprising: (a) at least one silicon-containing polyol, polyamine, polyepoxy or polyisocyanate having 1 or more functional groups and a molecular weight of at least 20,000 which is cured in the presence of: (b) at least one diol, diamine or diisocyanate having a molecular weight of less than 10,000; and/or (c) an initiator, processes for their preparation and their use in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of a soft tissue implant such as breast implants and the repair of orthopaedic joints such as spinal discs.Type: GrantFiled: August 6, 2018Date of Patent: March 24, 2020Assignee: Aortech International plcInventors: Mansour Mehrabi, Sriram Venkataramani, Mark Bown, Ajay D. Padsalgikar, Ramasri Mudumba
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Publication number: 20200032055Abstract: The present invention provides silicon-based polycarbonates, processes for their preparation and their use in the synthesis of copolymers, in particular segmented copolymers such as polyurethanes for biomedical applications.Type: ApplicationFiled: June 8, 2016Publication date: January 30, 2020Inventors: Francis P. Maguire, Sriram Venkataramani
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ALCOHOL-RESISTANT SILICONIZED POLYCARBONATE POLYURETHANES AND MEDICAL DEVICES INCORPORATING THE SAME
Publication number: 20190153147Abstract: An alcohol-resistant siliconized polycarbonate polyurethane can include a soft segment and a hard segment. The soft segment can include a polycarbonate polyol and a polysiloxane, which can be present in an amount less than the polycarbonate polyol. The hard segment can include an isocyanate and a chain extender. Peripherally inserted central catheter (PICC) devices can include one or more components that are at least partially formed from one or more formulations of the siliconized polycarbonate polyurethane catheter. The PICC devices can withstand alcohol locking, and can be power injectable both before and after alcohol locking events.Type: ApplicationFiled: November 19, 2018Publication date: May 23, 2019Inventors: Jay Allen Muse, Nathaniel J. Fredin, Sriram Venkataramani -
Publication number: 20190071543Abstract: The present invention relates to biostable gel comprising: (a) at least one silicon-containing polyol, polyamine, polyepoxy or polyisocyanate having 1 or more functional groups and a molecular weight of at least 20,000 which is cured in the presence of: (b) at least one diol, diamine or diisocyanate having a molecular weight of less than 10,000; and/or (c) an initiator, processes for their preparation and their use in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of a soft tissue implant such as breast implants and the repair of orthopaedic joints such as spinal discs.Type: ApplicationFiled: August 6, 2018Publication date: March 7, 2019Inventors: Mansour Mehrabi, Sriram Venkataramani, Mark Bown, Ajay D. Padsalgikar, Ramasri Mudumba
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Patent number: 10059807Abstract: The present invention relates to biostable gel comprising: (a) at least one silicon-containing polyol, polyamine, polyepoxy or polyisocyanate having 1 or more functional groups and a molecular weight of at least 20,000 which is cured in the presence of: (b) at least one diol, diamine or diisocyanate having a molecular weight of less than 10,000; and/or (c) an initiator, processes for their preparation and their use in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of a soft tissue implant such as breast implants and the repair of orthopedic joints such as spinal discs.Type: GrantFiled: July 7, 2016Date of Patent: August 28, 2018Assignee: Aortech International plcInventors: Mansour Mehrabi, Sriram Venkataramani, Mark Bown, Ajay D. Padsalgikar, Ramasri Mudumba
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Publication number: 20180179324Abstract: The present invention provides silicon-based polycarbonates, processes for their preparation and their use in the synthesis of copolymers, in particular segmented copolymers such as polyurethanes for biomedical applications.Type: ApplicationFiled: June 8, 2016Publication date: June 28, 2018Inventors: Francis P. Maguire, Sriram Venkataramani
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Patent number: 9765191Abstract: The present invention relates to biostable gel comprising: (a) at least one silicon-containing polyol, polyamine, polyepoxy or polyisocyanate having 1 or more functional groups and a molecular weight of at least 20,000 which is cured in the presence of: (b) at least one diol, diamine or diisocyanate having a molecular weight of less than 10,000; and/or (c) an initiator, processes for their preparation and their use in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of a soft tissue implant such as breast implants and the repair of orthopaedic joints such as spinal discs.Type: GrantFiled: January 6, 2014Date of Patent: September 19, 2017Assignee: Aortech International plcInventors: Mansour Mehrabi, Sriram Venkataramani, Mark Bown, Ajay D. Padsalgikar, Ramasri Mudumba
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Publication number: 20170121464Abstract: The present invention relates to biostable gel comprising: (a) at least one silicon-containing polyol, polyamine, polyepoxy or polyisocyanate having 1 or more functional groups and a molecular weight of at least 20,000 which is cured in the presence of: (b) at least one diol, diamine or diisocyanate having a molecular weight of less than 10,000; and/or (c) an initiator, processes for their preparation and their use in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of a soft tissue implant such as breast implants and the repair of orthopaedic joints such as spinal discs.Type: ApplicationFiled: July 7, 2016Publication date: May 4, 2017Inventors: Mansour Mehrabi, Sriram Venkataramani, Mark Bown, Ajay D. Padsalgikar, Ramasri Mudumba
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Publication number: 20170114187Abstract: The present invention relates to biostable gel comprising: (a) at least one silicon-containing polyol, polyamine, polyepoxy or polyisocyanate having 1 or more functional groups and a molecular weight of at least 20,000 which is cured in the presence of: (b) at least one diol, diamine or diisocyanate having a molecular weight of less than 10,000; and/or (c) an initiator, processes for their preparation and their use in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of a soft tissue implant such as breast implants and the repair of orthopaedic joints such as spinal discs.Type: ApplicationFiled: January 6, 2014Publication date: April 27, 2017Applicant: Aortech International plcInventors: Mansour Mehrabi, Sriram Venkataramani, Mark Bown, Ajay D. Padsalgikar, Ramasri Mudumba
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Patent number: 8882832Abstract: The invention relates to an implantable prosthesis and a shell for an implantable prosthesis and methods for making them, in particular a light weight implantable prosthesis containing a biocompatible filler which is suitable for use as a breast implant.Type: GrantFiled: July 25, 2012Date of Patent: November 11, 2014Assignee: Aortech International plcInventors: Ajay D. Padsalgikar, Frank Maguire, Sriram Venkataramani
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Publication number: 20140323676Abstract: The present invention relates to biostable gel comprising: (a) at least one silicon-containing polyol, polyamine, polyepoxy or polyisocyanate having 1 or more functional groups and a molecular weight of at least 20,000 which is cured in the presence of: (b) at least one diol, diamine or diisocyanate having a molecular weight of less than 10,000; and/or (c) an initiator, processes for their preparation and their use in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of a soft tissue implant such as breast implants and the repair of orthopaedic joints such as spinal discs.Type: ApplicationFiled: January 6, 2014Publication date: October 30, 2014Applicant: Aortech International plcInventors: Mansour Mehrabi, Sriram Venkataramani, Mark Bown, Ajay D. Padsalgikar, Ramasri Mudumba
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Patent number: 8623986Abstract: The present invention relates to biostable gel comprising: (a) at least one silicon-containing polyol, polyamine, polyepoxy or polyisocyanate having 1 or more functional groups and a molecular weight of at least 20,000 which is cured in the presence of: (b) at least one diol, diamine or diisocyanate having a molecular weight of less than 10,000; and/or (c) an initiator, processes for their preparation and their use in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of a soft tissue implant such as breast implants and the repair of orthopaedic joints such as spinal discs.Type: GrantFiled: April 19, 2007Date of Patent: January 7, 2014Assignee: Aertech International plcInventors: Mansour Mehrabi, Sriram Venkataramani, Mark Bown, Ajay Padsalgikar
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Patent number: 8207245Abstract: The present invention relates to silicon-containing biostable gels and processes for their preparation. The gels possess properties which make them useful in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of soft tissue implants such as breast implants and the repair of orthopaedic joints such as spinal discs.Type: GrantFiled: September 28, 2005Date of Patent: June 26, 2012Assignee: Aortech International plcInventors: Ajay Padsalgikar, Trang Thanh Nhan, Sriram Venkataramani, Mansour Mehrabi, Mark Bown
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Publication number: 20100029802Abstract: The present invention relates to biostable gel comprising: (a) at least one silicon-containing polyol, polyamine, polyepoxy or polyisocyanate having 1 or more functional groups and a molecular weight of at least 20,000 which is cured in the presence of: (b) at least one diol, diamine or diisocyanate having a molecular weight of less than 10,000; and/or (c) an initiator, processes for their preparation and their use in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of asoft tissue implant such as breast implants and the repair of orthopaedic joints such as spinal discs.Type: ApplicationFiled: April 19, 2007Publication date: February 4, 2010Inventors: Mansour Mehrabi, Sriram Venkataramani, Mark Bown, Ajay Padsalgikar
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Publication number: 20080293844Abstract: The present invention relates to silicon-containing biostable gels and processes for their preparation. The gels possess properties which make them useful in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of soft tissue implants such as breast implants and the repair of orthopaedic joints such as spinal discs.Type: ApplicationFiled: September 28, 2005Publication date: November 27, 2008Applicant: AORTECH BIOMATERIALS PTY LTDInventors: Ajay Padsalgikar, Trang Thanh Nhan, Sriram Venkataramani, Mansour Mehrabi, Mark Bown