Patents by Inventor Stacia Kargman

Stacia Kargman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for Treating or Preventing Neoplasias
    Publication number: 20090192158
    Abstract: The present invention is directed to a method for treating or preventing a neoplasia in a human patient in need of such treatment comprising administering to the patient a compound that inhibits microsomal prostaglandin E synthase-1 in an amount that is effective for treating or preventing the neoplasia.
    Type: Application
    Filed: April 30, 2007
    Publication date: July 30, 2009
    Inventors: Stacia Kargman, Gary O'Neill, Daigen Xu
  • Methods for identifying modulators of P2RY14
    Publication number: 20090148850
    Abstract: Methods for identifying modulators of P2RY14 are described. The methods are particularly useful for identifying agents that are useful for treating metabolic syndrome.
    Type: Application
    Filed: October 1, 2008
    Publication date: June 11, 2009
    Inventors: Stacia Kargman, Martine Hamel, Joseph A. Mancini, Christopher Bayly
  • Method of treating colonic adenomas
    Patent number: 6649649
    Abstract: This invention is directed to a method of retarding or preventing the transformation of a colonic adenoma to a colonic adenocarcinoma comprising the administration to a patient with FAP or a patient with one or more of said adenomas a non-toxic therapeutically effective amount of NSAID, said amount effective to inhibit the PGHS-2 in said adenoma. The preferred method comprises the administration of a specific PGHS-2 inhibiting agent as defined herein.
    Type: Grant
    Filed: March 2, 1999
    Date of Patent: November 18, 2003
    Assignees: Merck & Co., Inc., Merck Frosst Canada, & Co.
    Inventors: Stacia Kargman, Thomas J. Simon, Jilly Evans
  • Method of treating colonic adenomas
    Patent number: 6593361
    Abstract: This invention is directed to a method of retarding or preventing the transformation of a colonic adenoma to a colonic adenocarcinoma comprising the administration to a patient with FAP or a patient with one or more of said adenomas a non-toxic therapeutically effective amount of NSAID, said amount effective to inhibit the PGHS-2 in said adenoma. The preferred method comprises the administration of a specific PGHS-2 inhibiting agent as defined herein.
    Type: Grant
    Filed: October 12, 2001
    Date of Patent: July 15, 2003
    Inventors: Stacia Kargman, Jilly Evans, Thomas J. Simon
  • Method of treating colonic adenomas
    Publication number: 20020045605
    Abstract: This invention is directed to a method of retarding or preventing the transformation of a colonic adenoma to a colonic adenocarcinoma comprising the administration to a patient with FAP or a patient with one or more of said adenomas a non-toxic therapeutically effective amount of NSAID, said amount effective to inhibit the PGHS-2 in said adenoma. The preferred method comprises the administration of a specific PGHS-2 inhibiting agent as defined herein.
    Type: Application
    Filed: October 12, 2001
    Publication date: April 18, 2002
    Applicant: Merck & Co.
    Inventors: Stacia Kargman, Jilly Evans, Thomas J. Simon
  • Method of treating colonic adenomas
    Patent number: 5968974
    Abstract: This invention is directed to a method of retarding or preventing the transformation of a colonic adenoma to a colonic adenocarcinoma comprising the administration to a patient with FAP or a patient with one or more of said adenomas a non-toxic therapeutically effective amount of NSAID, said amount effective to inhibit the PGHS-2 in said adenoma. The preferred method comprises the administration of a specific PGHS-2 inhibiting agent as defined herein.
    Type: Grant
    Filed: October 10, 1997
    Date of Patent: October 19, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Stacia Kargman, Jilly Evans, Thomas J. Simon
  • Peptide sequences and antipeptide antisera for detecting human cyclooxygenase-1 and cyclooxygenase-2 proteins
    Patent number: 5459239
    Abstract: This invention discloses novel immunogenic peptide sequences, derived from the human cyclooxygenase-1 and cyclooxygenase-2 cDNAs which elicit specific non cross-reactive antibody responses. Assays are also disclosed for selectively and independently detecting cyclooxygenase-1 or cyclooxygenase-2 proteins present in a given biological sample.
    Type: Grant
    Filed: January 24, 1994
    Date of Patent: October 17, 1995
    Assignee: Merck Frosst Canada Inc.
    Inventors: Gary O'Neill, Philip J. Vickers, Stacia Kargman, Jillian F. Evans