Patents by Inventor Stanford S. Pelosi, Jr.

Stanford S. Pelosi, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-oxocyclic ureas useful as antiarrhythmic and antifibrillatory agents
    Patent number: 5462940
    Abstract: The 4-oxocyclic ureas and the pharmaceutically acceptable salts and esters thereof, of the present invention are useful as antiarrhythmic and antifibrillatory agents and have the following general structure: ##STR1## wherein X, Y, A, L, R, R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are defined as in the specification.
    Type: Grant
    Filed: June 3, 1994
    Date of Patent: October 31, 1995
    Assignee: Norwich Eaton Pharmaceuticals, Inc.
    Inventors: Chia-Nien Yu, Stanford S. Pelosi, Jr., Mark A. Calcagno
  • 5-phenyl-2-furan ketones and use as antiepileptic agents
    Patent number: 5091426
    Abstract: A method of preventing epileptic seizures in a human or lower animal subject susceptible to said seizures, comprising systemically administering to said subject a safe and effective amount of a compound of the formula: ##STR1## wherein (a) X is halo or nil, and Y is a substituent selected from the group consisting of unsubstituted or halogen-substituted methyl, halo, nitro, amino, and methoxy; and(b) R is R.sup.1 C(O)OH, R.sup.1 C(O)N(R.sup.2).sub.2, or R.sup.1 N(R.sup.2).sub.2 ; whereR.sup.1 is C.sub.1 -C.sub.3 alkylene which is unsubstituted or substituted with C.sub.1 -C.sub.2 alkyl; andeach R.sup.2 is, independently, hydrogen or lower alkyl; orboth R.sup.2 groups are connected to form a saturated 5- or 6-membered heterocycle containing 1 or 2 heteroatoms, wherein one of which is nitrogen and the other is selected from oxygen and nitrogen and said heterocycle is unsubstituted or substituted with lower alkyl or hydroxy-substituted lower alkyl;or a pharmaceutically-acceptable salt thereof.
    Type: Grant
    Filed: June 23, 1989
    Date of Patent: February 25, 1992
    Assignee: Norwich Eaton Pharmaceuticals, Inc.
    Inventor: Stanford S. Pelosi, Jr.
  • Use of 5-phenyl-2-furan esters and amides as antiepileptic agents
    Patent number: 5023272
    Abstract: A method of preventing epileptic seizures in a human or mammal subject susceptible to said seizures, comprising systemically administering to said subject a safe and effective amount of a compound of the formula: ##STR1## wherein (a) X is halo or hydrogen, and Y is a substituent selected from the group consisting of unsubstituted or halogen-substituted methyl, halo, nitro, amino, and methoxy; and(b) R is N(R.sup.3).sub.2, OR.sup.1 N(R.sup.3).sub.2, N(R.sup.2)R.sup.1 N(R.sup.3).sub.2, or N(R.sup.2)N(R.sup.3).sub.2 ; whereR.sup.1 is C.sub.1 -C.sub.3 alkylene which is unsubstituted or substituted with C.sub.1 -C.sub.2 alkyl;R.sup.2 is hydrogen or lower alkyl; andeach R.sup.3 is, independently, hydrogen or lower alkyl; or both R.sup.
    Type: Grant
    Filed: June 23, 1989
    Date of Patent: June 11, 1991
    Assignee: Norwich Eaton Pharmaceuticals, Inc.
    Inventors: Homer A. Burch, Alan W. Castellion, Stanford S. Pelosi, Jr.
  • 2-(5-phenyl-2-furanyl)imidazoles useful as cardiotonic agents
    Patent number: 4895867
    Abstract: The present invention involves certain 2-(5-phenyl-2-furanyl)-imidazoles, pharmaceutical compositions containing such compounds, and methods for enhancing the contractile force of cardiac muscle of a mammal which comprises systemically administering such compounds to a mammal.
    Type: Grant
    Filed: January 19, 1988
    Date of Patent: January 23, 1990
    Assignee: Norwich Eaton Pharmaceuticals, Inc.
    Inventors: Chau-Ting Huang, Stanford S. Pelosi, Jr., Ralph L. White, Jr.
  • N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents
    Patent number: 4882354
    Abstract: The present invention involves certain N-hydroxy-5-phenyl-2-furancarboximidamides, pharmaceutical compositions containing such compounds, and methods for increasing the contractile force of cardiac muscle of a mammal which comprises systemically administering such compounds to a mammal.
    Type: Grant
    Filed: December 16, 1987
    Date of Patent: November 21, 1989
    Assignee: Norwich Eaton Pharmaceuticals, Inc.
    Inventors: Chau-Ting Huang, Stanford S. Pelosi, Jr., Allan V. Bayless
  • 5-phenyl-2-furoic acid hydrazides
    Patent number: 4643996
    Abstract: Certain 5-phenyl-2-furoic acid hydrazides of the formula: ##STR1## wherein X represents 4-chloro, 4-fluoro, 3-trifluoromethyl or hydrogen, R.sub.1 represents hydrogen or methyl, R.sub.2 represents acetyl, isopropyl or methyl, and R.sub.1 and R.sub.2 taken together represent isopropylidene or 4-pyridinylmethylene are useful as anti-inflammatory agents.
    Type: Grant
    Filed: June 18, 1982
    Date of Patent: February 17, 1987
    Assignee: Norwich Eaton Pharmaceuticals, Inc.
    Inventors: Stanford S. Pelosi, Jr., Chia-Nien Yu
  • 2-[2-(5-Phenylfurfurylamino)ethyl]pyridines
    Patent number: 4439608
    Abstract: 2-[2-(5-Phenylfurfurylamino)ethyl]pyridines are useful as antihypertensive agents.
    Type: Grant
    Filed: June 4, 1982
    Date of Patent: March 27, 1984
    Assignee: Norwich Eaton Pharmaceuticals, Inc.
    Inventors: Stanford S. Pelosi, Jr., Chia-Nien Yu
  • 5-(4-Aminophenyl)-2-thiophenecarboximidamide hydrochloride hemihydrate
    Patent number: 4424367
    Abstract: 5-(4-Aminophenyl)-2-thiophenecarboximidamide hydrochloride hemihydrate is useful as an antidepressant agent.
    Type: Grant
    Filed: August 19, 1982
    Date of Patent: January 3, 1984
    Assignee: Norwich Eaton Pharmaceuticals, Inc.
    Inventors: Stanford S. Pelosi, Jr., Chia-Nien Yu, Ronald E. White, George C. Wright
  • 5-(3-Trifluoromethylphenyl)-2-furancarboxylic acid 2-(1-methylethylidene)hydrazide
    Patent number: 4403097
    Abstract: 5-(3-Trifluoromethylphenyl)-2-furancarboxylic acid 2-(1-methylethylidene)hydrazide is an effective skeletal muscle relaxant.
    Type: Grant
    Filed: June 4, 1982
    Date of Patent: September 6, 1983
    Assignee: Norwich Eaton Pharmaceuticals, Inc.
    Inventors: Stanford S. Pelosi, Jr., Chia-Nien Yu
  • 3-[[5-(4-Chlorophenyl)furfurylidene] amino]-5-(substituted)-2-oxazolidinones
    Patent number: 4393204
    Abstract: 3-[[5-(4-Chlorophenyl)furfurylidene]amino]-5-(substituted)-2-oxazolidinones are useful as antiinflammatory agents.
    Type: Grant
    Filed: May 21, 1982
    Date of Patent: July 12, 1983
    Assignee: Norwich Eaton Pharmaceuticals, Inc.
    Inventor: Stanford S. Pelosi, Jr.
  • 5-Phenyl-2-furancarboximidamides
    Patent number: 4217286
    Abstract: Certain 5-phenyl-2-furancarboximidamides of the formula: ##STR1## wherein X represents 2-nitro, 2-amino or 4-amino; R.sub.1 represents hydrogen or butyl; R.sub.2 represents butyl, hexyl or 3,4-dichlorobenzyl are effective antibacterial agents.
    Type: Grant
    Filed: January 25, 1977
    Date of Patent: August 12, 1980
    Assignee: Morton-Norwich Products, Inc.
    Inventors: Stanford S. Pelosi, Jr., Ronald E. White, George C. Wright, Chia N. Yu
  • N,N-dimethyl-5-phenyl-2-furamides
    Patent number: 4162257
    Abstract: N,N-Dimethyl-5-phenyl-2-furamides are useful as anti-inflammatory agents.
    Type: Grant
    Filed: July 10, 1978
    Date of Patent: July 24, 1979
    Assignee: Morton-Norwich Products, Inc.
    Inventors: Stanford S. Pelosi, Jr., Chia-Nien Yu
  • 5-(4-Chlorophenyl)furfurylurea
    Patent number: 4161479
    Abstract: 5-(4-Chlorophenyl)furfurylurea us useful as an anti-inflammatory agent.
    Type: Grant
    Filed: July 10, 1978
    Date of Patent: July 17, 1979
    Assignee: Morton-Norwich Products, Inc.
    Inventor: Stanford S. Pelosi, Jr.
  • 2-??5-(4-Chlorophenyl)furfurylamino!methyl!pyridine dihydrochloride
    Patent number: 4145348
    Abstract: 2-??5-(4-Chlorophenyl)furfurylamino!methyl!pyridine dihydrochloride is useful as an anti-inflammatory agent.
    Type: Grant
    Filed: July 10, 1978
    Date of Patent: March 20, 1979
    Assignee: Morton-Norwich Products, Inc.
    Inventors: Stanford S. Pelosi, Jr., Chia-Nien Yu
  • 1-Methyl-4-piperidyl 5-phenyl-2-furoates
    Patent number: 4128550
    Abstract: The title compounds are useful as anti-inflammatory agents.
    Type: Grant
    Filed: February 21, 1978
    Date of Patent: December 5, 1978
    Assignee: Morton-Norwich Products, Inc.
    Inventor: Stanford S. Pelosi, Jr.
  • 3-[5-(4-Nitrophenyl)furfurylamino)]-1,2-propanediol hydrochloride
    Patent number: 4111964
    Abstract: 3-[5-(4-Nitrophenyl)furfurylamino]-1,2-propanediol hydrochloride is an effective skeletal muscle relaxant.
    Type: Grant
    Filed: September 27, 1977
    Date of Patent: September 5, 1978
    Assignee: Morton-Norwich Products, Inc.
    Inventor: Stanford S. Pelosi, Jr.
  • 1-?5-(4-Chlorophenyl)furfurylamino!-2-propanol hydrochloride
    Patent number: 4097499
    Abstract: 1-?5-(4-Chlorophenyl)furfurylamino!-2-propanol hydrochloride is useful as an anti-inflammatory agent.
    Type: Grant
    Filed: August 1, 1977
    Date of Patent: June 27, 1978
    Assignee: Morton-Norwich Products, Inc.
    Inventor: Stanford S. Pelosi, Jr.
  • N-Methyl-5-(4-nitrophenyl)-N-(a-methylphenethyl)furfurylamine hydrochloride
    Patent number: 4097500
    Abstract: N-Methyl-5-(4-nitrophenyl)-N-(a-methylphenethyl)furfurylamine hydrochloride is useful as an antidepressant agent.
    Type: Grant
    Filed: July 25, 1977
    Date of Patent: June 27, 1978
    Assignee: Morton-Norwich Products, Inc.
    Inventor: Stanford S. Pelosi, Jr.
  • 5-(5-Halogenatedphenyl-2-furanyl)dihydro-2(3H)-furanones
    Patent number: 4085118
    Abstract: 5-(5-Halogenatedphenyl-2-furanyl)dihydro-2(3H)-furanones are useful as anti-inflammatory agents.
    Type: Grant
    Filed: December 17, 1976
    Date of Patent: April 18, 1978
    Assignee: Morton-Norwich Products, Inc.
    Inventor: Stanford S. Pelosi, Jr.
  • 5-(2-Nitrophenyl)-2-furancarboximidoyl morpholine or pyrrolidine hydrochloride
    Patent number: 4078141
    Abstract: 5-(2-Nitrophenyl)-2-furancarboximidoyl morpholine or pyrrolidine hydrochloride are useful as antidepressants.
    Type: Grant
    Filed: January 25, 1977
    Date of Patent: March 7, 1978
    Assignee: Morton-Norwich Products, Inc.
    Inventors: Stanford S. Pelosi, Jr., Ronald E. White, George C. Wright, Chia Nien Yu