Abstract: A method of treating a burn injury comprises administering to the injury a composition comprising petroleum wax, paraffin oil and a topically acceptable refrigerant, wherein subsequent evaporation of the refrigerant is effective to form a foam and maintain the foam at a temperature of from 0.degree. to 10.degree. C. for at least 1 minute. A suitable composition for use in the method comprises an intimate mixture of(a) petroleum wax in an amount of from 3 to 8% by weight of the composition, from 15 to 60% by weight of said wax being in microcrystalline form,(b) paraffin oil in an amount of from 6 to 15% by weight of the composition, and(c) the topically acceptable refrigerant or mixture of refrigerants.