Patents by Inventor Stanley J. Korsmeyer

Stanley J. Korsmeyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Animal models for loss and gain of Hox11 function
    Patent number: 5850002
    Abstract: Genetically engineered animals are described that have lost the expression of a homeobox gene and are missing an organ whose development is regulated by that homeobox gene. Such animals are models for organogenesis and can be used in methods for screening for compounds and gene therapies that restore the function of the missing organ. Other genetically engineered animals are described which express a homeobox gene in cells not normally expressing the gene and exhibit a developmental and/or pathologic condition in those cells. Such animals are models for gain of homeobox function and can be used in methods to screen for compounds and gene therapies that affect the developmental and/or pathologic condition due to the gain of homeobox gene expression.
    Type: Grant
    Filed: September 13, 1996
    Date of Patent: December 15, 1998
    Assignee: Washington University
    Inventor: Stanley J. Korsmeyer
  • Bcl-x/bcl-2 associated cell death regulator
    Patent number: 5834209
    Abstract: The invention provides a bcl-2 related protein, Bad, Bad muteins, two-hybrid systems comprising interacting Bad polypeptide sequences, Bad polynucleotides, and uses thereof.
    Type: Grant
    Filed: June 10, 1996
    Date of Patent: November 10, 1998
    Assignee: Washington University
    Inventor: Stanley J. Korsmeyer
  • Cell death regulator
    Patent number: 5700638
    Abstract: The invention provides a bcl-2 related protein, bcl-2 muteins, and uses thereof.
    Type: Grant
    Filed: May 25, 1994
    Date of Patent: December 23, 1997
    Assignee: Washington University
    Inventor: Stanley J. Korsmeyer
  • Cell death regulators
    Patent number: 5691179
    Abstract: A Bcl-2 associated protein (Bax) and uses thereof.
    Type: Grant
    Filed: August 26, 1993
    Date of Patent: November 25, 1997
    Assignee: Washington University
    Inventor: Stanley J. Korsmeyer
  • Bcl-x/Bcl-2 associated cell death regulator
    Patent number: 5622852
    Abstract: The invention provides a bcl-2 related protein, Bad, Bad muteins, two-hybrid systems comprising interacting Bad polypeptide sequences, Bad polynucleotides, and uses thereof.
    Type: Grant
    Filed: October 31, 1994
    Date of Patent: April 22, 1997
    Assignee: Washington University
    Inventor: Stanley J. Korsmeyer