Patents by Inventor Stanley J. Watowich

Stanley J. Watowich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Small-molecule inhibitors of dengue virus proteases
    Patent number: 9408813
    Abstract: The present invention concerns methods and compositions involving small molecule inhibitors for the treatment or prophylaxis of flavivirus infection, such as dengue virus and West Nile virus.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: August 9, 2016
    Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Stanley J. Watowich, Usha Viswanathan
  • SMALL-MOLECULE INHIBITORS OF DENGUE VIRUS PROTEASES
    Publication number: 20150141521
    Abstract: The present invention concerns methods and compositions involving small molecule inhibitors for the treatment or prophylaxis of flavivirus infection, such as dengue virus and West Nile virus.
    Type: Application
    Filed: November 13, 2014
    Publication date: May 21, 2015
    Inventors: Stanley J. Watowich, Usha Viswanathan
  • Small-molecule inhibitors of Dengue and West Nile virus proteases
    Patent number: 8778876
    Abstract: The present invention concerns methods and compositions involving small molecule inhibitors for the treatment or prophylaxis of flavivirus infection, such as dengue virus and West Nile virus.
    Type: Grant
    Filed: March 5, 2012
    Date of Patent: July 15, 2014
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Stanley J. Watowich, Suzanne M. Tomlinson, Scott Gilbertson
  • SMALL-MOLECULE INHIBITORS OF DENGUE AND WEST NILE VIRUS PROTEASES
    Publication number: 20130035284
    Abstract: The present invention concerns methods and compositions involving small molecule inhibitors for the treatment or prophylaxis of flavivirus infection, such as dengue virus and West Nile virus.
    Type: Application
    Filed: March 5, 2012
    Publication date: February 7, 2013
    Applicant: The Board of Regents of the University of Texas System
    Inventors: Stanley J. Watowich, Suzanne M. Tomlinson, Scott Gilbertson
  • Viral pseudo-capsids including assembly agonists and antagonists
    Patent number: 6849429
    Abstract: Recombinant hepatitis C virus (HCV) capsid proteins that self-assemble into large spherical virus-like particles structures and viral capsids that include conformational antigenic epitopes are provided. The large spherical virus-like particles structures and viral capsids, including capsid proteins that are expression products of a viral particle coding sequence protein, may be prepared as vaccines to induce a cellular or humoral immune response. The self assembling capsid proteins may also be used as elements of diagnostic immunoassay procedures for HCV infection.
    Type: Grant
    Filed: November 15, 2000
    Date of Patent: February 1, 2005
    Assignee: Board of Regents, The University of Texas System
    Inventors: Stanley J. Watowich, Meghan Kunkel, Marta Lorinczi
  • Drug discovery methods
    Publication number: 20020192799
    Abstract: The present invention provides collections of polypeptides, where each polypeptide includes a region Xaan, wherein n is from about 5 to about 21, and each Xaa is independently a random amino acid. Polynucleotides encoding the polypeptides, are also provided, as are methods for identifying a polypeptide within a collection that prevents cell death after exposure to a pathogen or a toxin, and methods for identifying a polypeptide within a collection that binds a pathogen, a toxin, a polypeptide, or a polynucleotide. The present invention also provides methods for crystallizing a polypeptide.
    Type: Application
    Filed: October 15, 2001
    Publication date: December 19, 2002
    Applicant: Board of Regents, The University of Texas System
    Inventors: Stanley J. Watowich, Scott C. Weaver, Robert A. Davey