Abstract: Antifungal nail coat compositions containing an allylamine, an N,N-di(C1-C8) alkylamino substituted, (C4-C18) alkyl (C2-C18) carboxylic ester or a pharmaceutically acceptable acid addition salt thereof, a hydrophilic polymer, and a pharmaceutically acceptable, volatile organic carrier are disclosed. The composition provides a substantially water-soluble, fungicidal coating upon contact with a fungally susceptible or infected nail.

Abstract: Antifungal nail coat compositions containing an allylamine, an N,N-di(C1-C8) alkylamino substituted, (C4-C18) alkyl (C2-C18) carboxylic ester or a pharmaceutically acceptable acid addition salt thereof, a hydrophilic polymer, and a pharmaceutically acceptable, volatile organic carrier are disclosed. The composition provides a substantially water-soluble, fungicidal coating upon contact with a fungally susceptible or infected nail.

Abstract: A dual action antifungal nail coat composition and method of use for ameliorating or preventing fungal infection of the nails, and onychomycosis, in particular, is disclosed. Composition embodiments in the form of one-coat type and two-coat type suitable for daily fungicidal regimens are disclosed. A preferred antifungal nail coat composition comprises an effective fungicidal amount of antifungal agent, a permeation enhancing amount of a substantially non-volatile, permeation enhancer, a film-forming amount of a hydrophilic polymer, and a pharmaceutically acceptable, volatile carrier. The composition provides a substantially water-soluble fungicidal coating on contacting a fungally susceptible or infected nail.

Abstract: The present invention relates to a method and system of manufacturing a cosmetic applicator in which a predetermined pattern of flocking bristles are dispensed toward the applicator and are adhered to the applicator by an adhesive. The flocking bristles can be dispensed using a flocking dispenser. The flocking dispenser is moveable in a longitudinal direction forward and backward along the sides and tip of the applicator. During or after movement of the flocking dispenser, the applicator can be rotated around its longitudinal axis. The movement of the flocking dispenser and rotation of the applicator can be controlled to provide the desired pattern of flocking bristles. The density of distribution of the flocking bristles can be controlled by varying the speed of movement and rotation of the applicator and the amount of flocking bristles which are dispensed from the flocking dispenser. For example, a high density of flocking bristles can be applied to extend radially from the tip.

Abstract: The present invention relates to a method and system of manufacturing a cosmetic applicator in which a predetermined pattern of flocking bristles are dispensed toward the applicator and are adhered to the applicator by an adhesive. The flocking bristles can be dispensed using a flocking dispenser. The flocking dispenser is moveable in a longitudinal direction forward and backward along the sides and tip of the applicator. During or after movement of the flocking dispenser, the applicator can be rotated around its longitudinal axis. The movement of the flocking dispenser and rotation of the applicator can be controlled to provide the desired pattern of flocking bristles. The density of distribution of the flocking bristles can be controlled by varying the speed of movement and rotation of the applicator and the amount of flocking bristles which are dispensed from the flocking dispenser. For example, a high density of flocking bristles can be applied to extend radially from the tip.