Patents by Inventor Stefan DIEPENBROCK
Stefan DIEPENBROCK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11776283Abstract: The present application relates to a method for the cytometric analysis of multiple cell samples by a microscope for examining multiple cell samples under a microscope, wherein the microscope can be or is operated, selectively and/or alternatingly, in a transmission mode and/or in a fluorescence mode, and wherein at least one cell sample has at least one fluorescence marker. The method includes; moving the cell samples continuously in one plane relative to an optical system of the microscope having at least one microscope camera, wherein, during the movement of the cell samples, at least one or more images of a sub-region of the cell samples are recorded in the transmission mode or in the fluorescence mode and at least one or more images of the same sub-region of the cell samples are recorded in the fluorescence mode by at least one microscope camera.Type: GrantFiled: April 22, 2021Date of Patent: October 3, 2023Assignee: OLYMPUS SOFT IMAGING SOLUTIONS GMBHInventors: Mike Woerdemann, Stefan Diepenbrock, Sascha Hofling, Daniel Kruger
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Patent number: 11216693Abstract: The invention relates to a method for providing at least one evaluation method for samples (2) in at least one optical application system (5) of a microscope-based application technology, where the following steps are performed: developing the evaluation method at least by an automated training (130) of an evaluation means (60) for an evaluation (120) of a specific type of sample on the basis of the application technology by an optical training system (4), the training (130) determining a training information (200) which at least partially defines the evaluation method, at least the training information (200) for distributing (140) the evaluation method to the at least one application system (5), wherein the provision takes place as a function of the type of sample and of the application technology.Type: GrantFiled: July 26, 2019Date of Patent: January 4, 2022Assignee: OLYMPUS SOFT IMAGING SOLUTIONS GmbHInventors: Daniel Krueger, Mike Woerdemann, Stefan Diepenbrock
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Patent number: 11199689Abstract: The invention relates to a method for microscopic evaluation (120) of a sample (2), in particular at least one uncolored object or cell sample (2), in an optical detection system (1), where the following steps are performed: providing at least two different detection information (110) about the sample (2), in particular by the detection system (1), performing an evaluation (120) of the detection information (110), in particular by an analysis means (60), on the basis of machine-learned transfer information (200), in order to determine result information (140) about the sample (2), the transfer information (200) being trained for a different detection parameterization of the detection information (110), in which the detection information (110) differs from one another in terms of at least one illumination parameter of the detection system (1), in particular in terms of polarization and/or color coding.Type: GrantFiled: July 19, 2019Date of Patent: December 14, 2021Assignee: Olympus Soft Imaging Solutions GmbHInventors: Daniel Krueger, Mike Woerdemann, Stefan Diepenbrock
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Patent number: 11113506Abstract: The invention concerns a method for providing an evaluation means (60) for at least one optical application system (5) of a microscope-based application technology, wherein the following steps are performed, in particular each by an optical training system (4): performing an input detection (101) of at least one sample (2) according to the application technology in order to obtain at least one input record (110) of the sample (2) from the input detection (101), performing a target detection (102) of the sample (2) according to a training technology to obtain at least one target record (112) of the sample (2) from the target detection (102), the training technology being different from the application technology at least in that additional information (115) about the sample (2) is provided, training (130) of the evaluation means (60) at least on the basis of the input recording (110) and the target recording (112), in order to obtain a training information (200) of the evaluation means (60), in that varioType: GrantFiled: August 6, 2019Date of Patent: September 7, 2021Assignee: OLYMPUS SOFT IMAGING SOLUTIONS GmbHInventors: Daniel Krueger, Mike Woerdemann, Stefan Diepenbrock
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Publication number: 20210248351Abstract: The present application relates to a method for the cytometric analysis of multiple cell samples by a microscope for examining multiple cell samples under a microscope, wherein the microscope can be or is operated, selectively and/or alternatingly, in a transmission mode and/or in a fluorescence mode, and wherein at least one cell sample has at least one fluorescence marker. The method includes; moving the cell samples continuously in one plane relative to an optical system of the microscope having at least one microscope camera, wherein, during the movement of the cell samples, at least one or more images of a sub-region of the cell samples are recorded in the transmission mode or in the fluorescence mode and at least one or more images of the same sub-region of the cell samples are recorded in the fluorescence mode by at least one microscope camera.Type: ApplicationFiled: April 22, 2021Publication date: August 12, 2021Applicant: OLYMPUS SOFT IMAGING SOLUTIONS GMBHInventors: Mike WOERDEMANN, Stefan DIEPENBROCK, Sascha HOFLING, Daniel KRUGER
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Patent number: 11023705Abstract: The present application relates to a method for the cytometric analysis of multiple cell samples by a microscope for examining multiple cell samples under a microscope, wherein the microscope can be or is operated, selectively and/or alternatingly, in a transmission mode and/or in a fluorescence mode, and wherein at least one cell sample has at least one fluorescence marker. The method includes; moving the cell samples continuously in one plane relative to an optical system of the microscope having at least one microscope camera, wherein, during the movement of the cell samples, at least one or more images of a sub-region of the cell samples are recorded in the transmission mode or in the fluorescence mode and at least one or more images of the same sub-region of the cell samples are recorded in the fluorescence mode by the at least one microscope camera.Type: GrantFiled: April 4, 2018Date of Patent: June 1, 2021Assignee: OLYMPUS SOFT IMAGING SOLUTIONS GMBHInventors: Mike Woerdemann, Stefan Diepenbrock, Sascha Hoefling, Daniel Krueger
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Publication number: 20200050830Abstract: The invention concerns a method for providing an evaluation means (60) for at least one optical application system (5) of a microscope-based application technology, wherein the following steps are performed, in particular each by an optical training system (4): performing an input detection (101) of at least one sample (2) according to the application technology in order to obtain at least one input record (110) of the sample (2) from the input detection (101), performing a target detection (102) of the sample (2) according to a training technology to obtain at least one target record (112) of the sample (2) from the target detection (102), the training technology being different from the application technology at least in that additional information (115) about the sample (2) is provided, training (130) of the evaluation means (60) at least on the basis of the input recording (110) and the target recording (112), in order to obtain a training information (200) of the evaluation means (60), in that variouType: ApplicationFiled: August 6, 2019Publication date: February 13, 2020Inventors: Daniel Krueger, Mike Woerdemann, Stefan Diepenbrock
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Publication number: 20200050891Abstract: The invention relates to a method for providing at least one evaluation method for samples (2) in at least one optical application system (5) of a microscope-based application technology, where the following steps are performed: developing the evaluation method at least by an automated training (130) of an evaluation means (60) for an evaluation (120) of a specific type of sample on the basis of the application technology by an optical training system (4), the training (130) determining a training information (200) which at least partially defines the evaluation method, at least the training information (200) for distributing (140) the evaluation method to the at least one application system (5), wherein the provision takes place as a function of the type of sample and of the application technology.Type: ApplicationFiled: July 26, 2019Publication date: February 13, 2020Inventors: Daniel Krueger, Mike Woerdemann, Stefan Diepenbrock
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Publication number: 20200026057Abstract: The invention relates to a method for microscopic evaluation (120) of a sample (2), in particular at least one uncolored object or cell sample (2), in an optical detection system (1), where the following steps are performed: providing at least two different detection information (110) about the sample (2), in particular by the detection system (1), performing an evaluation (120) of the detection information (110), in particular by an analysis means (60), on the basis of machine-learned transfer information (200), in order to determine result information (140) about the sample (2), the transfer information (200) being trained for a different detection parameterization of the detection information (110), in which the detection information (110) differs from one another in terms of at least one illumination parameter of the detection system (1), in particular in terms of polarization and/or color coding.Type: ApplicationFiled: July 19, 2019Publication date: January 23, 2020Inventors: Daniel Krueger, Mike Woerdemann, Stefan Diepenbrock
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Publication number: 20180293426Abstract: The present application relates to a method for the cytometric analysis of multiple cell samples by means of a microscope for examining multiple cell samples under a microscope, wherein the microscope can be or is operated, selectively and/or alternatingly, in a transmission mode and/or in a fluorescence mode, and wherein at least one cell sample has at least one fluorescence marker. The method includes; moving the cell samples continuously in one plane relative to an optical system of the microscope having at least one microscope camera, wherein, during the movement of the cell samples, at least one or more images of a sub-region of the cell samples are recorded in the transmission mode or in the fluorescence mode and at least one or more images of the same sub-region of the cell samples are recorded in the fluorescence mode by means of the at least one microscope camera.Type: ApplicationFiled: April 4, 2018Publication date: October 11, 2018Applicant: OLYMPUS SOFT IMAGING SOLUTIONS GMBHInventors: Mike WOERDEMANN, Stefan DIEPENBROCK, Sascha HOEFLING, Daniel KRUEGER