Abstract: Nanofluidic passages such as nanochannels and nanopores are closed or opened in a controlled manner through the use of a feedback system. An oxide layer is grown or removed within a passage in the presence of an electrolyte until the passage reaches selected dimensions or is closed. The change in dimensions of the nanofluidic passage is measured during fabrication. The ionic current level through the passage can be used to determine passage dimensions. Fluid flow through an array of fluidic elements can be controlled by selective oxidation of fluidic passages between elements.

Abstract: Remote access of a service provider to a secure enterprise computing environment through a firewall through the use of tokens.

Abstract: Nanofluidic passages such as nanochannels and nanopores are closed or opened in a controlled manner through the use of a feedback system. An oxide layer is grown or removed within a passage in the presence of an electrolyte until the passage reaches selected dimensions or is closed. The change in dimensions of the nanofluidic passage is measured during fabrication. The ionic current level through the passage can be used to determine passage dimensions. Fluid flow through an array of fluidic elements can be controlled by selective oxidation of fluidic passages between elements.

Abstract: A method for digital image classification and localization includes receiving a digital image of a biological organism from an imaging apparatus, the digital image comprising a plurality of intensities on a 2-dimensional grid of points, generating a plurality of discriminative representations of the 2D digital image by extracting dominant characteristics of the image from three different viewpoints, where the plurality of discriminative representations form a 3-dimensional digital image, combining the 3D digital image with the 2D digital image in a convolutional neural network that outputs a 3-channel feature map that localizes image abnormalities in each of the three channels and includes a detection confidence that each abnormalities is a neoplasm, providing the 3-channel feature map to a controller of a robotic surgical device where the robotic surgical device uses the 3-channel feature map to locate the neoplasm within the biological organism in a surgical procedure for treating the neoplasm.

Abstract: A method for neuromodulation includes monitoring brain activity of a patient using one or more electrodes attached to the patient, and using a first machine learning model to predict whether a patient will have a seizure based on the monitored brain activity of the patient. The method also includes, responsive to the first machine learning model predicting that the patient will have a seizure, using a second machine learning model to determine a neuromodulation signal pattern for preventing the predicted seizure. The method further includes using a neurostimulator to apply the determined neuromodulation signal pattern to the patient. The method also includes, after applying the determined neuromodulation signal pattern to the patient, detecting whether the patient had the predicted seizure based on the monitored brain activity of the patient. The method further includes adjusting at least the second machine learning model based on whether the patient had the predicted seizure.

Abstract: A method and system for improving a digital media content transfer blocking process is provided. The method includes detecting a request for access to digital media content from a digital media provider system. Network traffic across the network is identified and it is verified that the digital media content is comprised by the network traffic. In response, investigation platform software code is executed and a database system associated with the digital media provider system is queried. A system determines if a legitimate connection based relationship exists between a user device and the digital media provider system and the digital media content is monitored. The digital media content is determined to be unauthorized for use by said user and in response the digital media content is disabled from executing functions with respect to the user device of a user.

Abstract: A nanodevice includes a reservoir filled with conductive fluid and a membrane separating the reservoir. A nanopore is formed through the membrane having electrode layers separated by insulating layers. A certain electrode layer has a first type of organic coating and a pair of electrode layers has a second type. The first type of organic coating forms a motion control transient bond to a molecule in the nanopore for motion control, and the second type forms first and second transient bonds to different bonding sites of a base of the molecule. When a voltage is applied to the pair of electrode layers a tunneling current is generated by the base in the nanopore, and the tunneling current travels via the first and second transient bonds formed to be measured as a current signature for distinguishing the base. The motion control transient bond is stronger than first and second transient bonds.

Abstract: A method and system for improving a digital media content transfer blocking process is provided. The method includes detecting a request for access to digital media content from a digital media provider system. Network traffic across the network is identified and it is verified that the digital media content is comprised by the network traffic. In response, investigation platform software code is executed and a database system associated with the digital media provider system is queried. A system determines if a legitimate connection based relationship exists between a user device and the digital media provider system and the digital media content is monitored. The digital media content is determined to be unauthorized for use by said user and in response the digital media content is disabled from executing functions with respect to the user device of a user.

Abstract: A system, method and program product for evaluating IT platforms such as hybrid clouds and edge platforms. A system is disclosed that includes an ingestion engine that utilizes natural language processing to capture capabilities associated with a set of platforms; a modeling system for storing capabilities in a structured model that includes a set of IT categories and a set of IT features in each IT category; an analysis system that generates a compliance analysis by evaluating policies and requirements of an enterprise against capabilities stored in the structured model; and a visualization system that generates a graphical view of the IT categories and IT features, wherein the graphical view further includes a visualization of the compliance analysis.

Abstract: A method and system for improving a digital media content transfer blocking process is provided. The method includes detecting a request for access to digital media content from a digital media provider system. Network traffic across the network is identified and it is verified that the digital media content is comprised by the network traffic. In response, investigation platform software code is executed and a database system associated with the digital media provider system is queried. A system determines if a legitimate connection based relationship exists between a user device and the digital media provider system and the digital media content is monitored. The digital media content is determined to be unauthorized for use by said user and in response the digital media content is disabled from executing functions with respect to the user device of a user.

Abstract: Sorting device comprising several sorting carts, which can be moved along a sorting track in a transport direction and in each case are provided with a load receiving device for controlled receipt and delivery of individually packaged goods, with a quantity of discharge points at which individually packaged goods can be specifically delivered according to a respective sorting destination from the sorting carts, wherein each discharge point has a width, wherein the width of at least some discharge points can be adjusted while the sorting device is operating, and method for sorting individually packaged goods using the device.

Abstract: A method for making a single molecule receptor in a nanopore structure includes depositing a material by a physical vapor deposition (PVD) technique onto a selected interior surface of a nanochannel and functionalizing a surface of the material with a chemical compound having at least two functional groups. The material forms a patch having a diameter of about 3 to about 10,000 nanometers (nm). Also disclosed are embodiments of a nanopore structure including a single molecule receptor.

Abstract: A technique for a nanodevice is provided. The nanodevice includes a fluidic cell, and a membrane dividing the fluidic cell. A nanopore is formed through the membrane, and the nanopore is coated with an organic compound. A first part of the organic compound binds to a surface of the nanopore and a second part of the organic compound is exposed freely inside of the nanopore. The second part of the organic compound is configured to be switched among a first neutral hydrophilic end group, a second negatively charged hydrophilic end group, and a third neutral hydrophobic end group based on a switching mechanism.

Abstract: A technique for a nanodevice is provided. The nanodevice includes a fluidic cell, and a membrane dividing the fluidic cell. A nanopore is formed through the membrane, and the nanopore is coated with an organic compound. A first part of the organic compound binds to a surface of the nanopore and a second part of the organic compound is exposed freely inside of the nanopore. The second part of the organic compound is configured to be switched among a first neutral hydrophilic end group, a second negatively charged hydrophilic end group, and a third neutral hydrophobic end group based on a switching mechanism.

Abstract: A system for providing an alert to a user which includes a sensor for sensing user data pertaining to a user's condition; and a non-transitory storage medium that stores instructions. Also included is a processor that executes the instructions to: monitor the user data from the sensor for predefined conditions, at least one predefined condition pertaining to a mental state of the user; autonomously evaluate the user data for the predefined conditions; autonomously identify the predefined condition that matches the user's condition; autonomously determine a predefined alert corresponding to the predefined condition and to the user's condition to interact with the user to calm the user; and autonomously administer the predefined alert to the user.

Abstract: Translocation events are sensed using composite nanopore assemblies including nanopores formed in graphene sheets. Single molecule detection and characterization and multi-molecule characterization and identification are provided using such assemblies. Multiple electrodes associated with nanofluidic sensors facilitate detection of ionic current through a nanopore as well as tunneling currents. Current signals of individual molecules are estimated from the combination of an ionic current signal through the nanopore and tunneling current signals obtained at specific locations within the nanopore.

Abstract: A method, computer program product, and system for providing assistance during a multiparty communication include a processor(s) receiving, over a communications network data from a multiparty communication involving two or more participants, wherein the data comprises audio data. Among the processor(s) is a neuromorphic processor. The neuromorphic processor analyzes the data based on recognizing pre-defined speech patterns in the audio data and produces analytics based on the analysis of the data, during the multiparty communication, based on recognizing pre-defined speech patterns in the audio data. The processor(s) determines at least one sentiment of a first participant of the two or more participants participating in the multiparty communication. The processor(s) generates a visual representation of the multiparty communication that includes a representation of the at least one sentiment.

Abstract: Automatic scaling is performed on a floating point implementation of a DNN to perform scaling to a fixed point implementation. The DNN includes multiple layers in an order from a starting to an ending layer. The automatic scaling includes determining a scaling factor for each of multiple ones of the layers during training of the DNN. The scaling factor converts floating point numbers used for calculations in a layer into integer numbers to be used in the calculations. A scaling factor is determined for a selected layer, which is at a position in the order, based on scaling factors used in layers in the order prior to the position of the selected layer. The automatic scaling includes outputting the scaling factors for the multiple layers to be used for implementing the fixed point implementation of the DNN that uses integer calculations instead of floating point calculations.

Abstract: A system, method and program product for delivering haptic notifications to a user. A system is disclosed having: a plurality of wearable devices adapted to be worn on different parts of a user, wherein each wearable device is adapted to output a configurable haptic notification to the user; a host device that coordinates with at least two wearable devices to output a scheme of haptic notifications based on an associated rule in response to a detected event; and a learning system that analyzes feedback from the user to determine an efficacy of the scheme and causes the associated rule to be altered in response to the scheme being deemed ineffective.

Abstract: A method for making a single molecule receptor in a nanopore structure includes depositing a material by a physical vapor deposition (PVD) technique onto a selected interior surface of a nanochannel and functionalizing a surface of the material with a chemical compound having at least two functional groups. The material forms a patch having a diameter of about 3 to about 10,000 nanometers (nm). Also disclosed are embodiments of a nanopore structure including a single molecule receptor.