Patents by Inventor Stefan Leo VAN WORKUM
Stefan Leo VAN WORKUM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230358739Abstract: A sample management module for receiving a fluid sample for an immunoassay is provided. The module comprises: a sample reception device for receiving a sample; a detection reagent; a controller configured to initiate a reaction timer on the basis of an actuation event when the sample and detection reagent are brought into contact.Type: ApplicationFiled: December 18, 2020Publication date: November 9, 2023Applicant: Vidya Holdings LtdInventors: Stefan Leo Van Workum, Vladimir Alexander Turek, Marko Dorrestijn, David R. Klug
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Publication number: 20230358775Abstract: A storage and incubation device is provided. The device is configured to accommodate a plurality of assay chips, each assay chip including a unique identifier. The device comprises: a plurality of berths each sized to accommodate an assay chip; a communication module configured to receive information about the identifier of each assay chip; a clock timer configured to monitor the timing of the assay within each assay chip; a completion module to manage each assay chip when the assay is complete.Type: ApplicationFiled: December 18, 2020Publication date: November 9, 2023Applicant: Vidya Holdings LtdInventors: Stefan Leo Van Workum, Vladimir Alexander Turek, Marko Dorrestijn, David R. Klug
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Publication number: 20230346357Abstract: A combined sample collection and filtration device is provided for collecting and filtering a fluid sample. The device comprises: a sample collection location; a filter module for removing particulate matter from the fluid sample; the filter module having bubble point and a burst pressure; and one or more voids in communication with the sample collection location for accommodating sample during pressurisation such that the pressure within the device remains below the bubble point and the burst pressure of the filter module.Type: ApplicationFiled: August 20, 2021Publication date: November 2, 2023Applicant: VIDYA HOLDINGS LTDInventors: Marko Dorrestijn, David R. Klug, Vladimir Turek, Stefan Leo Van Workum
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Publication number: 20230321648Abstract: A lateral to free flow assay device is provided for analysis of a fluid sample. The device comprises: a sample collection unit configured to introduce the sample into the device; an optical element configured to facilitate TIR for the analysis of the sample; a fluid pathway configured to provide fluid communication between the sample collection unit and a free flow region adjacent the optical element; a wicking pad defining a lateral flow section of the fluid pathway or provided in the sample collection unit to collect the sample; wherein at least one surface of the optical element defines at least part of the free flow region of the fluid pathway; and wherein the fluid pathway is configured to enable fluid flow from the lateral flow region to the free flow region of the fluid pathway to facilitate the analysis of the sample.Type: ApplicationFiled: August 20, 2021Publication date: October 12, 2023Applicant: VIDYA HOLDINGS LTDInventors: Marko Dorrestijn, David Rupert Klug, Vladimir Turek, Stefan Leo Van Workum
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Publication number: 20230280338Abstract: An apparatus for creating and correcting a two dimensional intensity map of one or more assay spots in a detection zone is provided. The apparatus comprising, a locator for affirming the location of the detection zone; a total internal reflection excitation device comprising a light source for illuminating the one or more assay spots in the detection zone; a detector configured to receive light that is emitted, reflected or scattered from the one or more assay spots and to create a two dimensional intensity map of the one or more assay spots comprising a two dimensional array of quantitative pixel values; and a processor configured to correct the intensity map to remove noise through analysis of corresponding pixel values from an earlier intensity map; wherein the analysis includes curve fitting.Type: ApplicationFiled: July 9, 2021Publication date: September 7, 2023Applicant: VIDYA HOLDINGS LTDInventors: Marko Dorrestijn, David R. Klug, Vladimir Turek, Stefan Leo Van Workum
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Publication number: 20230181866Abstract: A humidification system can include a heater base, a chamber, and a breathing circuit. The heater base includes a heater plate positioned in a recessed region, and a heat conductive portion of the chamber is configured to contact the heater plate. The heater base includes a guard configured to control movement of the chamber into and out of the recessed region. The guard includes an anti-racking mechanism. The chamber includes an inlet port, an outlet port. A downward extension extends into the chamber from the inlet port, and a baffle is disposed at a lower end of the downward extension. A component of the breathing circuit can include a conduit hanging end cap for shipping and storage. The end cap can include a hanging component to allow the breathing circuit component to be hung from a medical stand. The system can detect when breathing circuits are connected in reverse.Type: ApplicationFiled: October 12, 2022Publication date: June 15, 2023Inventors: John James JACKSON, Barry Shack MANON, Victor Rosales CORRALES, Stefan Leo VAN WORKUM, Michael John ANDRESEN, Stephen David EVANS, Mark Samuel HAMILTON, Paul Fleming BUCKLEY, Jason Allan KLENNER, Hamish OSBORNE, Samuel Graham BOGGS, James William STANTON, Joseph Nathaniel GRIFFITHS, Jonathan Andrew George LAMBERT, Nicholas Edward VAUGHAN, James Owen KEHOE, Francisco Ernesto DE LA PEÑA DE LA FUENTE, Nicholas James Michael MCKENNA, Rachael PORTER, Simon Mordechai STAM, David Robert KEMPS, Edwin Joseph LYONS, Madeleine Bess MARTIN, Ada Yiwen SHOU, Huang-Ku LIU
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Publication number: 20230021366Abstract: An apparatus (1) for detecting the presence and/or the quantity of a target component in a biological fluid in an integrated assay cartridge (52) of predetermined configuration, the assay cartridge comprising a capture component (22) at a predetermined location in the assay cartridge, the apparatus comprising: a detector (12)for detecting the amount of light scattered, transmitted or emitted by the sample to provide an indication of the presence and/or the quantity of the target component within the sample; three location positions (30), the three positions defining a location along the optical path of the detector on which to locate the cartridge of a predetermined size; wherein location positions are configured such that the capture component of the assay cartridge is located, in use, at the focal plane of the detector. Measures to ensure quality control may also be provided.Type: ApplicationFiled: December 18, 2020Publication date: January 26, 2023Applicant: Vidya Holdings LtdInventors: Stefan Leo Van Workum, Vladimir Alexander Turek, Marko Dorrestijn, David R. Klug
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Publication number: 20230016953Abstract: The present disclosure provides for an improved method of determining a water out condition in a humidified gases supply apparatus. The method includes a two-step process including a primary determination of a water out condition and a secondary determination of a water out condition. This primary determination is made during observation of the normal operation of the apparatus. During the secondary determination the method takes temporary control over the humidifying part of the apparatus. The secondary determination confirms or contradicts the primary determination.Type: ApplicationFiled: July 28, 2022Publication date: January 19, 2023Inventors: Po-Yen LIU, Ivan Chih-Fan TENG, Stefan Leo VAN WORKUM, Oliver Samuel STEINER, Anthony James NEWLAND
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Patent number: 11511069Abstract: A humidification system can include a heater base, a chamber, and a breathing circuit. The heater base includes a heater plate positioned in a recessed region, and a heat conductive portion of the chamber is configured to contact the heater plate. The heater base includes a guard configured to control movement of the chamber into and out of the recessed region. The guard includes an anti-racking mechanism. The chamber includes an inlet port, an outlet port. A downward extension extends into the chamber from the inlet port, and a baffle is disposed at a lower end of the downward extension. A component of the breathing circuit can include a conduit hanging end cap for shipping and storage. The end cap can include a hanging component to allow the breathing circuit component to be hung from a medical stand. The system can detect when breathing circuits are connected in reverse.Type: GrantFiled: September 15, 2014Date of Patent: November 29, 2022Assignee: Fisher & Paykel Healthcare LimitedInventors: John James Jackson, Barry Shack Manon, Victor Rosales Corrales, Stefan Leo Van Workum, Michael John Andresen, Stephen David Evans, Mark Samuel Hamilton, Paul Fleming Buckley, Jason Allan Klenner, Hamish Osborne, Samuel Graham Boggs, James William Stanton, Joseph Nathaniel Griffiths, Jonathan Andrew George Lambert, Nicholas Edward Vaughan, James Owen Kehoe, Francisco Ernesto De La Pe{hacek over (n)}a De La Fuente, Nicholas James Michael McKenna, Rachael Porter, Simon Mordechai Stam, David Robert Kemps, Edwin Joseph Lyons, Madeleine Bess Martin, Ada Yiwen Shou, Huang-Ku Liu
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Patent number: 11433196Abstract: The present disclosure provides for an improved method of determining a water out condition in a humidified gases supply apparatus. The method includes a two-step process including a primary determination of a water out condition and a secondary determination of a water out condition. This primary determination is made during observation of the normal operation of the apparatus. During the secondary determination the method takes temporary control over the humidifying part of the apparatus. The secondary determination confirms or contradicts the primary determination.Type: GrantFiled: July 19, 2017Date of Patent: September 6, 2022Assignee: FISHER & PAYKEL HEALTHCARE LIMITEDInventors: Po-Yen Liu, Ivan Chih-Fan Teng, Stefan Leo Van Workum, Oliver Samuel Steiner, Anthony James Newland
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Publication number: 20220146505Abstract: An assay cartridge for detecting a target component in a liquid sample is provided. The cartridge comprises: a sample collection unit configured to introduce the liquid sample into the cartridge; a fluid pathway commencing at its proximal end at the sample collection unit and extending distally through the cartridge including: one or more capture components immobilised within the fluid pathway; one or more detection reagents provided within the diffusion distance of the capture components.Type: ApplicationFiled: February 28, 2020Publication date: May 12, 2022Applicant: Vidya Holdings LtdInventors: Marko Dorrestijn, David R. Klug, Shao-Ju LU, Callum Robertson Smith, Stefan Leo Van Workum, Vlad Turek
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Publication number: 20220143608Abstract: A sample management module for collecting a fluid sample is provided. The module comprising; a sample collection device comprising a sample collection location; a decoupling zone configured to receive sample from the collection device, an overflow reservoir in fluid communication with the decoupling zone to accommodate any sample that does not fit into the decoupling zone; wherein the overflow reservoir is configured to ensure pressure within the module can be managed. A cartridge comprising a sample management module is also provided.Type: ApplicationFiled: February 28, 2020Publication date: May 12, 2022Applicant: Vidya Holdings LtdInventors: Stefan Leo Van Workum, Callum Robertson Smith, Marko Dorrestijn, David R. Klug
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Publication number: 20220146425Abstract: An assay cartridge for detecting a target component in a fluid is provided. The assay cartridge including an optical element comprising: a light pathway comprising an input surface, reflective surface and output surface configured to enable light to enter, reflect and create an evanescent field in the vicinity of the reflective surface and exit the element; a plurality of capture components deposited on the reflective surface in the vicinity of the evanescent field; and a transmission surface configured to enable emissions from the evanescent field to exit the element; wherein the assay cartridge is a single use cartridge.Type: ApplicationFiled: February 28, 2020Publication date: May 12, 2022Applicant: Vidya Holdings LtdInventors: Stefan Leo Van Workum, Callum Robertson Smith, Marko Dorrestijn, David R. Klug
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Publication number: 20220143597Abstract: An assay cartridge for detecting a target component in a liquid sample is provided. The cartridge comprises: a sample collection unit configured to introduce the liquid sample into the cartridge; a fluid pathway commencing at its proximal end at the sample collection unit and extending distally through the cartridge including: one or more capture components immobilised within the fluid pathway; one or more detection reagents provided proximally of or level with the capture components each contained within a liquid droplet.Type: ApplicationFiled: February 28, 2020Publication date: May 12, 2022Applicant: Vidya Holdings LtdInventors: Marko Dorrestijn, David R. Klug, Shao-Ju LU, Callum Robertson Smith, Stefan Leo Van Workum, Vlad Turek
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Publication number: 20210178107Abstract: A respiratory assistance system including a humidification apparatus used for delivery of heated and humidified gases to a patient includes a humidification chamber with an associated heater and sensor, an inspiratory conduit with an associated heater and sensor, and an unheated patient interface, such as a face mask. A controller of the humidification apparatus is configured to determine a gas source and change the set point accordingly to maintain patient comfort regardless of the humidity level of the gas source.Type: ApplicationFiled: December 23, 2020Publication date: June 17, 2021Inventors: Daniel John Smith, Anthony James Newland, Po-Yen Liu, Stefan Leo Van Workum, Ivan Chih-Fan Teng
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Patent number: 10905843Abstract: A respiratory assistance system including a humidification apparatus used for delivery of heated and humidified gases to a patient includes a humidification chamber with an associated heater and sensor, an inspiratory conduit with an associated heater and sensor, and an unheated patient interface, such as a face mask. A controller of the humidification apparatus is configured to determine a gas source and change the set point accordingly to maintain patient comfort regardless of the humidity level of the gas source.Type: GrantFiled: January 16, 2017Date of Patent: February 2, 2021Assignee: Fisher & Paykel Healthcare LimitedInventors: Daniel John Smith, Anthony James Newland, Po-Yen Liu, Stefan Leo Van Workum, Ivan Chih-Fan Teng
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Publication number: 20190262560Abstract: The present disclosure provides for an improved method of determining a water out condition in a humidified gases supply apparatus. The method includes a two-step process including a primary determination of a water out condition and a secondary determination of a water out condition. This primary determination is made during observation of the normal operation of the apparatus. During the secondary determination the method takes temporary control over the humidifying part of the apparatus. The secondary determination confirms or contradicts the primary determination.Type: ApplicationFiled: July 19, 2017Publication date: August 29, 2019Inventors: Po-Yen LIU, Ivan Chih-Fan TENG, Stefan Leo VAN WORKUM, Oliver Samuel STEINER, Anthony James NEWLAND
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Publication number: 20190076617Abstract: A respiratory assistance system including a humidification apparatus used for delivery of heated and humidified gases to a patient includes a humidification chamber with an associated heater and sensor, an inspiratory conduit with an associated heater and sensor, and an unheated patient interface, such as a face mask. A controller of the humidification apparatus is configured to determine a gas source and change the set point accordingly to maintain patient comfort regardless of the humidity level of the gas source.Type: ApplicationFiled: January 16, 2017Publication date: March 14, 2019Inventors: Daniel John Smith, Anthony James Newland, Po-Yen Liu, Stefan Leo Van Workum, Ivan Chih-Fan Teng
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Publication number: 20160228671Abstract: A humidification system can include a heater base, a chamber, and a breathing circuit. The heater base includes a heater plate positioned in a recessed region, and a heat conductive portion of the chamber is configured to contact the heater plate. The heater base includes a guard configured to control movement of the chamber into and out of the recessed region. The guard includes an anti-racking mechanism. The chamber includes an inlet port, an outlet port. A downward extension extends into the chamber from the inlet port, and a baffle is disposed at a lower end of the downward extension. A component of the breathing circuit can include a conduit hanging end cap for shipping and storage. The end cap can include a hanging component to allow the breathing circuit component to be hung from a medical stand. The system can detect when breathing circuits are connected in reverse.Type: ApplicationFiled: September 15, 2014Publication date: August 11, 2016Inventors: John James JACKSON, Barry Shack MANON, Victor Rosales CORRALES, Stefan Leo VAN WORKUM, Michael John ANDRESEN, Stephen David EVANS, Mark Samuel HAMILTON, Paul Fleming BUCKLEY, Jason Allan KLENNER, Hamish OSBORNE, Samuel Graham BOGGS, James William STANTON, Joseph Nathaniel GRIFFITHS, Jonathan Andrew George LAMBERT, Nicholas Edward VAUGHAN, James Owen KEHOE, Francisco Ernesto De La Pena DE LA FUENTE, Nicholas James Michael MCKENNA, Rachael PORTER, Simon Mordechai STAM, David Robert KEMPS, Edwin Joseph LYONS, Madeleine Bess MARTIN, Ada Yiwen SHOU, Huang-Ku LIU