Patents by Inventor Stefan SIKORRA

Stefan SIKORRA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NON-NEURONAL SNARE-CLEAVING BOTULINUM NEUROTOXINS
    Publication number: 20230312661
    Abstract: The present invention provides a modified botulinum neurotoxin A (BoNT/A) L-chain protease that demonstrates enhanced cleaveage of human SNAP-23 (hSNAP-23) relative to unmodified (wild-type) BoNT/A L-chain protease, together with the use thereof for cleaving hSNAP-23.
    Type: Application
    Filed: March 15, 2023
    Publication date: October 5, 2023
    Applicant: IPSEN BIOPHARM LIMITED
    Inventors: Thomas BINZ, Stefan SIKORRA
  • Non-neuronal snare-cleaving botulinum neurotoxins
    Patent number: 11634460
    Abstract: The present invention provides a modified botulinum neurotoxin A (BoNT/A) L-chain protease that demonstrates enhanced cleaveage of human SNAP-23 (hSNAP-23) relative to unmodified (wild-type) BoNT/A L-chain protease, together with the use thereof for cleaving hSNAP-23.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: April 25, 2023
    Assignee: IPSEN BIOPHARM LIMITED
    Inventors: Thomas Binz, Stefan Sikorra
  • NON-NEURONAL SNARE-CLEAVING BOTULINUM NEUROTOXINS
    Publication number: 20200239528
    Abstract: The present invention provides a modified botulinum neurotoxin A (BoNT/A) L-chain protease that demonstrates enhanced cleaveage of human SNAP-23 (hSNAP-23) relative to unmodified (wild-type) BoNT/A L-chain protease, together with the use thereof for cleaving hSNAP-23.
    Type: Application
    Filed: January 29, 2019
    Publication date: July 30, 2020
    Inventors: Thomas BINZ, Stefan SIKORRA