Patents by Inventor Stefan Steinhofer

Stefan Steinhofer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220204534
    Abstract: A process for a continuous production of a boronic acid derivative and an apparatus of performing the process are disclosed.
    Type: Application
    Filed: March 18, 2022
    Publication date: June 30, 2022
    Inventors: Andreas PELZ, Christian SCHUSTER, Stefan STEINHOFER, Clemens STUECKLER, Maria VASILOIU, Christopher ZINGANELL
  • Patent number: 11352373
    Abstract: A process for a continuous production of a boronic acid derivative and an apparatus of performing the process are disclosed.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: June 7, 2022
    Assignee: MELINTA SUBSIDIARY CORP.
    Inventors: Andreas Pelz, Christian Schuster, Stefan Steinhofer, Clemens Stueckler, Maria Vasiloiu, Christopher Zinganell
  • Patent number: 11312732
    Abstract: A process for a continuous production of a boronic acid derivative and an apparatus of performing the process are disclosed.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: April 26, 2022
    Assignee: MELINTA SUBSIDIARY CORP.
    Inventors: Andreas Pelz, Christian Schuster, Stefan Steinhofer, Clemens Stueckler, Maria Vasiloiu, Christopher Zinganell
  • Patent number: 10843999
    Abstract: The invention pertains to a process for preparing a compound of formula (1) wherein R1 is independently chosen from C1-C6 alkyl, cycloalkyl, aralkyl and aryl, and R2, R3 and R4 are independently chosen from hydrogen and C1-C6 alkyl, cycloalkyl, aralkyl and aryl; which process comprises the steps of: a) contacting a compound of formula (2) wherein R1 and R2 are as above and M+ is a monovalent metal ion, with a compound of formula (3) wherein R3 and R4 are as above, to form a compound of formula (4) and b) followed by contacting the compound of formula (4) with an acid to give a compound of formula (1), wherein step (a) and/or step (b) are conducted in continuous mode.
    Type: Grant
    Filed: February 12, 2018
    Date of Patent: November 24, 2020
    Assignee: Patheon Austria GmbH & Co KG
    Inventors: Paul Kohls, Peter Pöchlauer, Stefan Steinhofer, Christian Schuster
  • Publication number: 20200115393
    Abstract: A process for a continuous production of a boronic acid derivative and an apparatus of performing the process are disclosed.
    Type: Application
    Filed: January 31, 2018
    Publication date: April 16, 2020
    Inventors: Andreas PELZ, Christian SCHUSTER, Stefan STEINHOFER, Clemens STUECKLER, Maria VASILOIU, Christopher ZINGANELL
  • Publication number: 20200002263
    Abstract: The invention pertains to a process for preparing a compound of formula (1) wherein R1 is independently chosen from C1-C6 alkyl, cycloalkyl, aralkyl and aryl, and R2, R3 and R4 are independently chosen from hydrogen and C1-C6 alkyl, cycloalkyl, aralkyl and aryl; which process comprises the steps of: a) contacting a compound of formula (2) wherein R1 and R2 are as above and M+ is a monovalent metal ion, with a compound of formula (3) wherein R3 and R4 are as above, to form a compound of formula (4) and b) followed by contacting the compound of formula (4) with an acid to give a compound of formula (1), wherein step (a) and/or step (b) are conducted in continuous mode.
    Type: Application
    Filed: February 12, 2018
    Publication date: January 2, 2020
    Applicant: PATHEON AUSTRIA GMBH & CO KG
    Inventors: Paul Kohls, Peter Pöchlauer, Stefan Steinhofer, Christian Schuster
  • Patent number: 10364257
    Abstract: A process for a continuous production of a boronic acid derivative based on a Matteson boronic ester homologation and an apparatus of performing the process are disclosed.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: July 30, 2019
    Assignee: REMPEX PHARMACEUTICALS, INC.
    Inventors: Ulfried Felfer, Clemens Stueckler, Stefan Steinhofer, Andreas Pelz, Marcus Hanacek, Thomas Heinrich Pabst, George Winkler, Peter Poechlauer, Bas Ritzen, Michel Goldbach
  • Publication number: 20170369512
    Abstract: A process for a continuous production of a boronic acid derivative based on a Matteson boronic ester homologation and an apparatus of performing the process are disclosed.
    Type: Application
    Filed: December 9, 2015
    Publication date: December 28, 2017
    Inventors: Ulfried Felfer, Clemens Stueckler, Stefan Steinhofer, Andreas Pelz, Marcus Hanacek, Thomas Heinrich Pabst, George Winkler, Peter Poechlauer, Bas Ritzen, Michel Goldbach
  • Patent number: 8536366
    Abstract: A process for the continuous production of a compound of Formula (II), HO—R1—ONO2 (II) wherein R1 is a straight chain alkyl radical having from 3 to 6 carbon atoms, in a two-phase solvent system, comprising contacting a compound of Formula (I), HO—R1—OH (I) wherein R1 is as defined above, with nitric acid in the presence of a first solvent, wherein the compound of Formula (II) is continuously extracted into a second solvent, and the reaction is carried out in a mixing microreactor which provides a power loss of at least 1.3 times the power loss provided under identical conditions by a circular cross-section straight-channel microreactor having an internal diameter equal to the average hydraulic diameter of the mixing microreactor and a length equal to the length of the mixing microreactor.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: September 17, 2013
    Assignee: DSM Fine Chemicals Austria NFG GmbH & Co KG
    Inventors: Sascha Braune, Stefan Steinhofer, Peter Poechlauer, Rafael Wilhelmus E. G. Reintjens, Nicole Theodora W. Linssen, Mehul Thathagar
  • Patent number: 8221708
    Abstract: A tube bundle falling film microreactor for performing gas-liquid reactions, which has: a) at least one vertical tube with b) a device for distributing the liquid on the inside of the tube and c) a liquid collecting system, and d) a device for gas supply and removal, and use thereof.
    Type: Grant
    Filed: May 29, 2008
    Date of Patent: July 17, 2012
    Assignee: DSM Fine Chemicals Austria NFG GmbH & Co KG
    Inventors: Florian Seebauer, Peter Poechlauer, Sascha Braune, Stefan Steinhofer
  • Publication number: 20110034720
    Abstract: A process for the continuous production of a compound of Formula (II), HO—R1—ONO2 (II) wherein R1 is a straight chain alkyl radical having from 3 to 6 carbon atoms, in a two-phase solvent system, comprising contacting a compound of Formula (I), HO—R1—OH (I) wherein R1 is as defined above, with nitric acid in the presence of a first solvent, wherein the compound of Formula (II) is continuously extracted into a second solvent, and the reaction is carried out in a mixing microreactor which provides a power loss of at least 1.3 times the power loss provided under identical conditions by a circular cross-section straight-channel microreactor having an internal diameter equal to the average hydraulic diameter of the mixing microreactor and a length equal to the length of the mixing microreactor.
    Type: Application
    Filed: December 19, 2008
    Publication date: February 10, 2011
    Inventors: Sascha Braune, Stefan Steinhofer, Peter Poechlauer, Rafael Wilhelmus E.G. Reintjens, Nicole Theodora W. Linssen, Mehul Thathagar
  • Publication number: 20100152479
    Abstract: A tube bundle falling film microreactor for performing gas-liquid reactions, which has: a) at least one vertical tube with b) a device for distributing the liquid on the inside of the tube and c) a liquid collecting system, and d) a device for gas supply and removal, and use thereof.
    Type: Application
    Filed: May 28, 2008
    Publication date: June 17, 2010
    Inventors: Florian Seebauer, Peter Poechlauer, Sascha Braune, Stefan Steinhofer
  • Publication number: 20100130787
    Abstract: Reaction plates for microreactors for performing gas-liquid reactions, which consist of falling-film plates with a surface which has a randomly distributed, unordered fine structure or microstructure.
    Type: Application
    Filed: March 18, 2008
    Publication date: May 27, 2010
    Inventors: Sascha Braune, Stefan Steinhofer