Patents by Inventor Stefan Strobel

Stefan Strobel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VIRAL VECTORS AND NUCLEIC ACIDS FOR REGULATED GENE THERAPY
    Publication number: 20240076689
    Abstract: This invention generally relates to the field of somatic gene therapy. The invention provides a nucleic acid construct comprising a transgene encoding a therapeutic protein, a tetracycline-responsive aptazyme sequence, and inverted terminal repeats (ITRs). The nucleic acid construct can be transferred to a subject in need thereof in the form of a viral vector, in particular an adeno-associated virus (AAV) vector. The Tet-responsive aptazyme sequence allows for a tightly controlled expression of the transgene in the subject, thereby avoiding toxic side effects. The nucleic acid construct and the viral vectors comprising same are particularly useful in the treatment of proliferative diseases like cancer.
    Type: Application
    Filed: May 17, 2021
    Publication date: March 7, 2024
    Inventors: John Park, Philipp MÜLLER, Sebastian KREUZ, Benjamin STROBEL, Matthias DÜCHS, Matthias KLUGMANN, Stefan MICHELFELDER, Dragica BLAZEVIC, Romona KRATZER
  • Cutting tool with blade made of fine-crystalline diamond
    Patent number: 8904650
    Abstract: The present invention relates to a cutting tool, in particular in the form of a razor blade, a scalpel, a knife, a machine knife, scissors etc., which has a synthetic diamond layer with a cutting edge. The diamond layer thereby consists of fine-crystalline diamond.
    Type: Grant
    Filed: February 29, 2012
    Date of Patent: December 9, 2014
    Assignee: GFD Gesellschaft für Diamantprodukte mbH
    Inventors: André Flöter, Stefan Strobel, Peter Gluche
  • Cutting tool with blade made of fine-crystalline diamond
    Publication number: 20120276826
    Abstract: The present invention relates to a cutting tool, in particular in the form of a razor blade, a scalpel, a knife, a machine knife, scissors etc., which has a synthetic diamond layer with a cutting edge. The diamond layer thereby consists of fine-crystalline diamond.
    Type: Application
    Filed: February 29, 2012
    Publication date: November 1, 2012
    Applicant: GFD Gesellschaft für Diamantprodukte mbH.
    Inventors: André Flöter, Stefan Strobel, Peter Gluche
  • Instrument for surgical purposes and method of cleaning same
    Patent number: 6558380
    Abstract: An instrument for surgical purposes, especially for coagulation, is proposed. This instrument has at least one arm, the tips of the arms having electrical contact regions which can be electrically connected to a control unit for touching a tissue for the purpose of coagulation. The contact regions are formed from doped diamond to produce the electrical conductivity.
    Type: Grant
    Filed: December 8, 2000
    Date of Patent: May 6, 2003
    Assignee: GFD Gesellschaft fur Diamantprodukte mbH
    Inventors: Christian Lingenfelder, Stephan Ertl, Stefan Strobel, Rudolf Rösch, Siegfried Förster, Matthias Fryda, Lothar Schäfer, Inga Tröster, Dennie Herrmann
  • Instrument for surgical purposes and method of cleaning same
    Publication number: 20020072746
    Abstract: An instrument for surgical purposes, especially for coagulation, is proposed. This instrument has at least one arm (2), the tips (4) of the arms having electrical contact regions (6, 7), which can be electrically connected to a control unit (12), for touching a tissue (13) for the purpose of coagulation. The contact regions are formed from doped diamond to produce the electrical conductivity.
    Type: Application
    Filed: December 8, 2000
    Publication date: June 13, 2002
    Inventors: Christian Lingenfelder, Stephan Ertl, Stefan Strobel, Rudolf Rosch, Siegfried Forster, Matthias Fryda, Lothar Schafer, Inga Troster, Dennie Herrmann