Patents by Inventor Stefan Thiem
Stefan Thiem has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240085485Abstract: A method for determining the parameters of an equivalent circuit for representation of the impedance of a lithium ion cell is provided. The equivalent circuit includes at least one RC element having an ohmic resistor R1, a capacitor C1, and a series resistor Rs. The series resistor Rs is determined by an impedance measurement.Type: ApplicationFiled: September 24, 2020Publication date: March 14, 2024Inventors: Stefan ROEMERSPERGER, Jan Philipp SCHMIDT, Tobias THIEM, Christopher WAGNER
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Patent number: 8850848Abstract: The invention relates to an apparatus (10) for sectioning histological samples, which encompasses a sectioning unit (18), a sample holder (14), and a drive unit (16) for moving the sample holder (14) relative to the sectioning unit (18) in order to section the sample (12). Also provided is a cooling unit (20), for cooling at least a sub-region of the sample holder (14), which encompasses a compressor for compressing a refrigerant, a capillary tube (25) for delivering the liquefied refrigerant from the compressor (22) to the sample holder (14), and a return line (28) for returning the refrigerant from the sample holder (14) to the compressor (22). At least a sub-region (32) of the capillary tube (25) is embodied in a spiral shape.Type: GrantFiled: June 8, 2012Date of Patent: October 7, 2014Assignee: Leica Biosystems Nussloch GmbHInventors: Stefan Thiem, Christian Lorenz
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Patent number: 8722412Abstract: An apparatus for sensing specimen slides (38) has a specimen slide holder (42) holding specimen slides (38), each specimen slide (38) comprising an identification code. The specimen slides (38) are arranged inside the specimen slide holder (42) on a lifting element (50) in a lifted position. The apparatus includes a reading apparatus (40) for reading out the identification code, and a positioning apparatus that moves the specimen slide holder (42) with the specimen slides (38) relative to the lifting element (50) so that the specimen slides (38) drop successively from the lifted position on the lifting element (50). As one of the specimen slides (38) drops, the identification code of the specimen slide (38) or of the subsequent specimen slide (38) becomes readable for the reading apparatus (40). A triggering apparatus (67, 68) triggers the reading apparatus (40) to read the identification code.Type: GrantFiled: December 28, 2011Date of Patent: May 13, 2014Assignee: Leica Biosystems Nussloch GmbHInventors: Markus Egle, Stefan Thiem, Simon Keimer, Karl-Heinz Westerhoff
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Patent number: 8353232Abstract: The present invention relates to a device for braking or locking a shaft (6) of a microtome (1). The microtome (1) comprises the shaft (6), an actuating element (2), a movement mechanism (37) and a housing (38). With the movement mechanism (37) an object to be cut can be moved relative to a knife blade. The actuating element (2) can be manually actuated by an operator. As a result thereof, the shaft (6) can be rotated. Via the shaft (6), the movement mechanism (37) for performing the relative motion between the object and the knife blade can be driven. Further, the present invention relates to a method for operating a device for braking a shaft (6) of a microtome (1). So that the device can be used in a mechanically formed movement mechanism (37), the inventive device is characterized by an actuator and a braking unit (25). The braking unit (25) is connected in a rotatably fixed manner to the shaft (6).Type: GrantFiled: June 6, 2008Date of Patent: January 15, 2013Assignee: Leica Biosystems Nussloch GmbHInventors: Roland Walter, Stefan Thiem, Andreas Laudat
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Publication number: 20120318075Abstract: The invention relates to an apparatus (10) for sectioning histological samples, which encompasses a sectioning unit. (18), a. sample holder (14), and a drive unit (16) for moving the sample holder (14) relative to the sectioning unit (18) in order to section the sample (12). Also provided is a cooling unit (20), for cooling at least a sub-region of the sample holder (14), which encompasses a compressor for compressing a refrigerant, a capillary tube (25) for delivering the liquefied refrigerant from the compressor (22) to the sample holder (14), and a return line (28) for returning the refrigerant from the sample holder (14) to the compressor (22). At least a sub-region (32) of the capillary tube (25) is embodied in a spiral shape.Type: ApplicationFiled: June 8, 2012Publication date: December 20, 2012Applicant: LEICA BIOSYSTEMS NUSSLOCH GMBHInventors: Stefan THIEM, Christian LORENZ
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Publication number: 20120171003Abstract: An apparatus for sensing specimen slides (38) has a specimen slide holder (42) holding specimen slides (38), each specimen slide (38) comprising an identification code. The specimen slides (38) are arranged inside the specimen slide holder (42) on a lifting element (50) in a lifted position. The apparatus includes a reading apparatus (40) for reading out the identification code, and a positioning apparatus that moves the specimen slide holder (42) with the specimen slides (38) relative to the lifting element (50) so that the specimen slides (38) drop successively from the lifted position on the lifting element (50). As one of the specimen slides (38) drops, the identification code of the specimen slide (38) or of the subsequent specimen slide (38) becomes readable for the reading apparatus (40). A triggering apparatus (67, 68) triggers the reading apparatus (40) to read the identification code.Type: ApplicationFiled: December 28, 2011Publication date: July 5, 2012Applicant: Leica Biosystems Nusslock GmbHInventors: Markus EGLE, Stefan THIEM, Simon KEIMER, Karl-Heinz WESTERHOFF
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Patent number: 8187157Abstract: A microtome blade changing apparatus for a knife holder (1) of a microtome comprises a blade dispenser (4) storing unused blades and a blade container (5) for receiving used blades. The blade dispenser (4) and blade container (5) are respectively arranged adjacent to the knife holder (1). To reduce the risk of injury to an operator in the context of a blade changing operation, enable operation of the microtome blade changing apparatus reliably and in simple fashion, and allow economical manufacture of the microtome blade changing apparatus, the microtome blade changing apparatus is characterized in that an entraining element (13) manually actuable by an operator is provided, and is configured in such a way that an unused blade is transferable with the entraining element (13) from the blade dispenser (4) to the knife holder (1), and a used blade is thereby conveyable into the blade container (5).Type: GrantFiled: December 19, 2007Date of Patent: May 29, 2012Assignee: Leica Biosystems Nussloch GmbHInventors: Stefan Thiem, Rolf Metzner, Christoph Schmitt
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Patent number: 8042444Abstract: A knife holder (1) for microtome blades (2) has a body (3) for reception of the blade (2) against an abutment edge (4) and a pressure plate (5) for retention of the blade, such that in the retained state, only the blade cutting edge (6) protrudes from the body (3), and an ejection apparatus (8), associated with one side edge (7) of the blade cutting edge (6), is connected to the body (3).Type: GrantFiled: October 15, 2005Date of Patent: October 25, 2011Assignee: Leica Biosystems Nussloch GmbHInventor: Stefan Thiem
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Patent number: 7910060Abstract: An apparatus is described for treating prepared specimens. The apparatus comprises at least two container rows arranged in parallel to each other, each comprising a plurality of reagent containers and a transport mechanism for transporting at least one transport container that receives at least one carrier holding at least one prepared specimen. The transport mechanism is movable along an X and Z axis. A rotation unit is provided comprising holding arms and at least one holding element. The container rows are received rotatably at the ends of the holding arms of the at least one holding element that is connected to a rotation shaft such that it co-rotates with the rotation shaft that extends parallel to the X axis. The rotation unit is adapted to assume at least one working position allowing the transport mechanism to have access to the reagent container.Type: GrantFiled: September 14, 2009Date of Patent: March 22, 2011Assignee: Leica Biosystems Nussloch GmbHInventors: Simon Keimer, Harald Rauh, Eberhard Sendobry, Jürgen Tenhaef, Stefan Thiem
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Publication number: 20100180742Abstract: The present invention relates to a device for braking or locking a shaft (6) of a microtome (1). The microtome (1) comprises the shaft (6), an actuating element (2), a movement mechanism (37) and a housing (38). With the movement mechanism (37) an object to be cut can be moved relative to a knife blade. The actuating element (2) can be manually actuated by an operator. As a result thereof, the shaft (6) can be rotated. Via the shaft (6), the movement mechanism (37) for performing the relative motion between the object and the knife blade can be driven. Further, the present invention relates to a method for operating a device for braking a shaft (6) of a microtome (1). So that the device can be used in a mechanically formed movement mechanism (37), the inventive device is characterized by an actuator and a braking unit (25). The braking unit (25) is connected in a rotatably fixed manner to the shaft (6).Type: ApplicationFiled: June 6, 2008Publication date: July 22, 2010Applicant: LEICA BIOSYSTEMS NUSSLOCH GMBHInventors: Roland Walter, Stefan Thiem, Andreas Laudat
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Publication number: 20100068094Abstract: An apparatus is described for treating prepared specimens. The apparatus comprises at least two container rows arranged in parallel to each other, each comprising a plurality of reagent containers and a transport mechanism for transporting at least one transport container that receives at least one carrier holding at least one prepared specimen. The transport mechanism is movable along an X and Z axis. A rotation unit is provided comprising holding arms and at least one holding element. The container rows are received rotatably at the ends of the holding arms of the at least one holding element that is connected to a rotation shaft such that it co-rotates with the rotation shaft that extends parallel to the X axis. The rotation unit is adapted to assume at least one working position allowing the transport mechanism to have access to the reagent container.Type: ApplicationFiled: September 14, 2009Publication date: March 18, 2010Applicant: LEICA BIOSYSTEMS NUSSLOCH GMBHInventors: Simon Keimer, Harald Rauh, Eberhard Sendobry, Jürgen Tenhaef, Stefan Thiem
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Publication number: 20090235799Abstract: A knife holder (1) for microtome blades (2) is described, which holder has a body (3) for reception of the blade (2) against an abutment edge (4) and a pressure plate (5) for retention of the blade, such that in the retained state, only the blade cutting edge (6) protrudes from the body (3), and an ejection apparatus (8), associated with one side edge (7) of the blade cutting edge (6), is arranged on the body (3).Type: ApplicationFiled: October 15, 2005Publication date: September 24, 2009Applicant: LEICA BIOSYSTEMS NUSSLOCH GMBHInventor: Stefan Thiem
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Publication number: 20080148918Abstract: A microtome blade changing apparatus for a knife holder (1) of a microtome comprises a blade dispenser (4) storing unused blades and a blade container (5) for receiving used blades. The blade dispenser (4) and blade container (5) are respectively arranged adjacent to the knife holder (1). To reduce the risk of injury to an operator in the context of a blade changing operation, enable operation of the microtome blade changing apparatus reliably and in simple fashion, and allow economical manufacture of the microtome blade changing apparatus, the microtome blade changing apparatus is characterized in that an entraining element (13) manually actuable by an operator is provided, and is configured in such a way that an unused blade is transferable with the entraining element (13) from the blade dispenser (4) to the knife holder (1), and a used blade is thereby conveyable into the blade container (5).Type: ApplicationFiled: December 19, 2007Publication date: June 26, 2008Applicant: LEICA BIOSYSTEMS NUSSLOCH GMBHInventors: Stefan Thiem, Rolf Metzner, Christoph Schmitt
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Patent number: 7368081Abstract: A system (100) for staining and coverslipping specimen slides comprises a first part (the stainer (1)) and a second part (the coverslipper (20)). A transport device (5), with which racks (4) carrying specimen slides are transferred directly from the stainer (1) into the coverslipper (20), is provided in the stainer (1).Type: GrantFiled: November 29, 2006Date of Patent: May 6, 2008Assignee: Leica Biosystems Nussloch GmbHInventor: Stefan Thiem
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Patent number: 7357384Abstract: A device for signaling the position of an orientable sample holder for a microtome is described. The drive system (2) for moving the sample holder is arranged in a housing. At least one rotatably mounted spindle (4), and a nut (5) running on the spindle (4), are provided for moving the sample holder in one spatial direction. The nut (5) comprises a position element (6) identifying the zero position, and an indicating element (11) is associated with the position element (6).Type: GrantFiled: May 17, 2004Date of Patent: April 15, 2008Assignee: Leica Biosystems Nussloch GmbHInventor: Stefan Thiem
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Patent number: 7273000Abstract: A rotary microtome (1) is disclosed, having a base part (2) on which a microtome housing (4) and a knife holder (6) are arranged. Also provided is a collection element (8) that surrounds the knife holder on three sides, the collection element having a U-shaped base outline. Also provided are several clamping levers that are associated with the knife holder, at least one clamping lever for the knife holder being arranged operably on a first or a second outer side wall (18a, 18b). In addition, the bottom (12) of the collection element (8) has shaped on it an elevation (22) under which a mechanical coupling is guided from the clamping lever (10c) to the knife holder.Type: GrantFiled: April 14, 2004Date of Patent: September 25, 2007Assignee: Leica Microsystems Nussloch GmbHInventors: Stefan Thiem, Roland Walter, Rolf Metzner
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Publication number: 20070098599Abstract: A system (100) for staining and coverslipping specimen slides comprises a first part (the stainer (1)) and a second part (the coverslipper (20)). A transport device (5), with which racks (4) carrying specimen slides are transferred directly from the stainer (1) into the coverslipper (20), is provided in the stainer (1).Type: ApplicationFiled: November 29, 2006Publication date: May 3, 2007Inventor: Stefan Thiem
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Patent number: 7198752Abstract: For automatic transportation and lifting and lowering of specimens in an automatic stainer, a drive system comprises a motor (16) and a side wall assembly (40), the motor (16) being coupled on the drive side to a first (12) and a second (14) crank system. The first (12) and second (14) crank systems are respectively coupled to the side wall assembly (40).Type: GrantFiled: July 1, 2003Date of Patent: April 3, 2007Assignee: Leica Microsystems Nussloch GmbHInventor: Stefan Thiem
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Patent number: 7153474Abstract: A system (100) for staining and coverslipping specimen slides comprises a first part (the stainer (1)) and a second part (the coverslipper (20)). A transport device (5), with which racks (4) carrying specimen slides are transferred directly from the stainer (1) into the coverslipper (20), is provided in the stainer (1).Type: GrantFiled: August 29, 2002Date of Patent: December 26, 2006Assignee: Leica Microsystems Nussloch GmbHInventor: Stefan Thiem
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Patent number: 6887428Abstract: An apparatus for treating objects, in particular cytological or histological specimens, having multiple processing stations (2) and a transport device (4) for delivering the objects into and out of the processing stations (2), is characterized in that the transport device (4) comprises a robot arm (5) that is movable in three dimensions and provides for arbitrary positioning of the objects.Type: GrantFiled: August 20, 2001Date of Patent: May 3, 2005Assignee: Leica Microsystems Nussloch GmbHInventors: Martin Wernz, Stefan Thiem, Eric Barth