Patents by Inventor Stefanie Sydlik

Stefanie Sydlik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metal Chelating Functional Graphene Materials
    Publication number: 20230226519
    Abstract: Described herein is a functional graphene composition comprising a graphene scaffold and one or more metal chelating functional groups covalently bonded to the graphene scaffold and a porous substrate that includes the functional graphene composition. Also provided is a method of removing dissolved metals from an aqueous liquid, such as, acid mine drainage.
    Type: Application
    Filed: June 4, 2021
    Publication date: July 20, 2023
    Inventors: Stefanie A. Sydlik, Anne M. Arnold, Edward P. Zovinka, Michelle M. Karpinsky
  • Chelator-functionalized glycosaminoglycans
    Patent number: 11479617
    Abstract: A compound includes a polysaccharide moiety and one or more chelating agents. The one or more chelating agents are covalently bonded to the polysaccharide moiety. The polysaccharide moiety can include a glycosaminoglycan moiety, such as a hyaluronic acid polymer or a sulfated glycosaminoglycan moiety. The compound can be used to treat or prevent a disease or disorder in a patient with a metal implant. The compound reduces a concentration of metal particulates or metal ions in the subject.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: October 25, 2022
    Assignees: Carnegie Mellon University, University of Connecticut
    Inventors: Stefanie A. Sydlik, Anne M. Arnold, Brian D. Holt, Cato T. Laurencin, Leila Daneshmandi, Stephen Schmidt
  • Therapeutic acrylates as enhanced medical adhesives
    Patent number: 11292760
    Abstract: Provided herein are therapeutic acrylate compounds useful as medical adhesives, comprising a therapeutic agent covalently linked to a methacrylate or cyanoacrylate moiety. Adhesive compositions and kits, such as liquid sutures and bone cement also are provided along with uses for the compositions.
    Type: Grant
    Filed: September 13, 2017
    Date of Patent: April 5, 2022
    Assignee: Carnegie Mellon University
    Inventors: Stefanie A. Sydlik, Zoe Wright
  • PHOSPHATE FUNCTIONALIZED GRAPHENE OXIDE BASED BONE SCAFFOLDS
    Publication number: 20200069838
    Abstract: A method for functionalizing graphene oxide includes reacting graphene oxide with a phosphite compound and a metal salt in the presence of a Lewis acid to produce phosphate functionalized graphene oxide including ions of the metal. An apparatus includes a bone scaffold construct formed of phosphate functionalized graphene oxide including metal ions. A bone scaffold construct includes a graphene oxide material formed in the shape of the bone scaffold construct, the graphene oxide material including graphene oxide, phosphate moieties covalently bound to the graphene oxide, and metal counter ions chemically associated with the phosphate moieties. A method for treating a bone defect includes administering a therapeutically effective amount of phosphate functionalized graphene oxide including metal ions.
    Type: Application
    Filed: May 3, 2018
    Publication date: March 5, 2020
    Inventors: Anne M. Arnold, Brian D. Holt, Stefanie A. Sydlik, Cato T. Laurencin, Leila Daneshmandi
  • CHELATOR-FUNCTIONALIZED GLYCOSAMINOGLYCANS
    Publication number: 20200062869
    Abstract: A compound includes a polysaccharide moiety and one or more chelating agents. The one or more chelating agents are covalently bonded to the polysaccharide moiety. The polysaccharide moiety can include a glycosaminoglycan moiety, such as a hyaluronic acid polymer or a sulfated glycosaminoglycan moiety. The compound can be used to treat or prevent a disease or disorder in a patient with a metal implant. The compound reduces a concentration of metal particulates or metal ions in the subject.
    Type: Application
    Filed: August 27, 2019
    Publication date: February 27, 2020
    Inventors: Stefanie A. Sydlik, Anne M. Arnold, Brian D. Holt, Cato T. Laurencin, Leila Daneshmandi, Stephen Schmidt
  • Therapeutic Acrylates as Enhanced Medical Adhesives
    Publication number: 20190262497
    Abstract: Provided herein are therapeutic acrylate compounds useful as medical adhesives, comprising a therapeutic agent covalently linked to a methacrylate or cyanoacrylate moiety. Adhesive compositions and kits, such as liquid sutures and bone cement also are provided along with uses for the compositions.
    Type: Application
    Filed: September 13, 2017
    Publication date: August 29, 2019
    Inventors: Stefanie A. Sydlik, Zoe Wright
  • Compositions comprising functionalized carbon-based nanostructures and related methods
    Patent number: 9770709
    Abstract: The present invention generally relates to compositions comprising and methods for forming functionalized carbon-based nanostructures.
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: September 26, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: Timothy M. Swager, William R. Collins, Wiktor Lewandowski, Ezequiel Schmois, Stefanie Sydlik, Joseph Walish, John B. Goods
  • COMPOSITIONS COMPRISING FUNCTIONALIZED CARBON-BASED NANOSTRUCTURES AND RELATED METHODS
    Publication number: 20150336092
    Abstract: The present invention generally relates to compositions comprising and methods for forming functionalized carbon-based nanostructures.
    Type: Application
    Filed: March 26, 2015
    Publication date: November 26, 2015
    Applicant: Massachusetts Institute of Technology
    Inventors: Timothy M. Swager, William R. Collins, Wiktor Lewandowski, Ezequiel Schmois, Stefanie Sydlik, Joseph Walish, John B. Goods
  • Compositions comprising and methods for forming functionalized carbon-based nanostructures
    Patent number: 8476510
    Abstract: The present invention generally relates to compositions comprising and methods for forming functionalized carbon-based nanostructures.
    Type: Grant
    Filed: November 3, 2011
    Date of Patent: July 2, 2013
    Assignee: Massachusetts Institute of Technology
    Inventors: Timothy M. Swager, William R. Collins, Wiktor Lewandowski, Ezequiel Schmois, Stefanie Sydlik, Joseph Walish, John B. Goods
  • COMPOSITIONS COMPRISING FUNCTIONALIZED CARBON-BASED NANOSTRUCTURES AND RELATED METHODS
    Publication number: 20120171093
    Abstract: The present invention generally relates to compositions comprising and methods for forming functionalized carbon-based nanostructures.
    Type: Application
    Filed: November 3, 2011
    Publication date: July 5, 2012
    Applicant: Massachusetts Institute of Technology
    Inventors: Timothy M. Swager, William R. Collins, Wiktor Lewandowski, Ezequiel Schmois, Stefanie Sydlik, Joseph Walish, John B. Goods
  • COMPOSITIONS COMPRISING AND METHODS FOR FORMING FUNCTIONALIZED CARBON-BASED NANOSTRUCTURES
    Publication number: 20120116094
    Abstract: The present invention generally relates to compositions comprising and methods for forming functionalized carbon-based nanostructures.
    Type: Application
    Filed: November 3, 2011
    Publication date: May 10, 2012
    Applicant: Massachusetts Institute of Technology
    Inventors: Timothy M. Swager, William R. Collins, Wiktor Lewandowski, Ezequiel Schmois, Stefanie Sydlik, Joseph Walish, John B. Goods