Patents by Inventor Steffen Helmling

Steffen Helmling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ghrelin binding nucleic acids
    Publication number: 20120115937
    Abstract: The present invention is related to a nucleic acid, preferably binding to ghrelin, whereby the nucleic acid comprises a first stretch Box A, and a second stretch Box B, whereby the first stretch Box A comprises about 25 consecutive nucleotides, the second stretch Box B comprises about six to eight consecutive nucleotides, whereby a 3?-terminal stretch of nucleotides of the first stretch Box A hybridises with the second stretch Box B, whereby upon hybridisation a first double-stranded structure is formed, whereby such first double-stranded structure comprises a bulge.
    Type: Application
    Filed: January 24, 2012
    Publication date: May 10, 2012
    Applicant: NOXXON PHARMA AG
    Inventors: Florian Jarosch, Dirk Eulberg, Christian Maasch, Steffen Helmling, Sven Klussmann
  • Ghrelin binding nucleic acids
    Publication number: 20120083520
    Abstract: The present invention is related to a nucleic acid antagonist of ghrelin.
    Type: Application
    Filed: May 8, 2010
    Publication date: April 5, 2012
    Applicant: NOXXON PHARMA AG
    Inventors: Steffen Helmling, Dirk Eulberg, Christian Maasch, Sven Klussmann
  • Ghrelin binding nucleic acids
    Patent number: 8101734
    Abstract: The present invention is related to a nucleic acid, preferably binding to ghrelin, whereby the nucleic acid comprises a first stretch Box A, and a second stretch Box B, whereby the first stretch Box A comprises about 25 consecutive nucleotides, the second stretch Box B comprises about six to eight consecutive nucleotides, whereby a 3?-terminal stretch of nucleotides of the first stretch Box A hybridizes with the second stretch Box B, whereby upon hybridization a first double-stranded structure is formed, whereby such first double-stranded structure comprises a bulge.
    Type: Grant
    Filed: April 7, 2006
    Date of Patent: January 24, 2012
    Assignee: NOXXON Pharma AG
    Inventors: Florian Jarosch, Dirk Eulberg, Christian Maasch, Steffen Helmling, Sven Klussmann
  • CGRP binding nucleic acids
    Patent number: 7879991
    Abstract: The invention relates to an antagonist for CGRP and amylin, whereby the antagonist is a nucleic acid and said nucleic acid binds to CGRP or amylin. Said nucleic acid preferably comprises an L-nucleotide.
    Type: Grant
    Filed: May 6, 2003
    Date of Patent: February 1, 2011
    Assignee: NOXXON Pharma AG
    Inventors: Axel Vater, Christian Maasch, Florian Jarosch, Mathias Bell, Steffen Helmling, Bernd Eschgfäller, Elisabeth Moyroud, Sandra Stark, Sven Klussmann, Thorsten Ruppert, Gregor Bahrenberg, Clemens Gillen, Klaus Schiene
  • Nucleic acids specifically binding bioactive ghrelin
    Publication number: 20100261291
    Abstract: The present invention is related to a nucleic acid specifically binding bioactive ghrelin, more preferably n-octanoyl ghrelin, and its use for the diagnosis of ghrelin mediated diseases and disorders.
    Type: Application
    Filed: February 24, 2010
    Publication date: October 14, 2010
    Applicant: NOXXON Pharma AG
    Inventors: SVEN KLUSSMANN, STEFFEN HELMLING, DIRK EULBERG, CHRISTIAN MAASCH, KLAUS BUCHNER
  • Ghrelin binding nucleic acids
    Patent number: 7750140
    Abstract: The present invention is related to an antagonist of ghrelin, wherein the antagonist is a nucleic acid, and whereby preferably the nucleic acid is binding to ghrelin.
    Type: Grant
    Filed: August 1, 2003
    Date of Patent: July 6, 2010
    Assignee: NOXXON Pharma AG
    Inventors: Steffen Helmling, Dirk Eulberg, Christian Maasch, Sven Klussmann
  • Nucleic acids specifically binding bioactive ghrelin
    Publication number: 20070031840
    Abstract: The present invention is related to a nucleic acid specifically binding bioactive ghrelin, more preferably n-octanoyl ghrelin, and its use for the diagnosis of grelin mediated diseases and disorders.
    Type: Application
    Filed: November 10, 2004
    Publication date: February 8, 2007
    Applicant: NOXXON Pharma AG
    Inventors: Sven Klussmann, Steffen Helmling, Dirk Eulberg, Christian Maasch, Klaus Buchner
  • Ghrelin binding nucleic acids
    Publication number: 20060258607
    Abstract: The present invention is related to a nucleic acid, preferably binding to ghrelin, whereby the nucleic acid comprises a first stretch Box A, and a second stretch Box B, whereby the first stretch Box A comprises about 25 consecutive nucleotides, the second stretch Box B comprises about six to eight consecutive nucleotides, whereby a 3?-terminal stretch of nucleotides of the first stretch Box A hybridises with the second stretch Box B, whereby upon hybridisation a first double-stranded structure is formed, whereby such first double-stranded structure comprises a bulge.
    Type: Application
    Filed: April 7, 2006
    Publication date: November 16, 2006
    Applicant: NOXXON Pharma AG
    Inventors: Florian Jarosch, Dirk Eulberg, Christian Maasch, Steffen Helmling, Sven Klussmann
  • Ghrelin binding nucleic acids
    Publication number: 20060257867
    Abstract: The present invention is related to an antagonist of ghrelin, wherein the antagonist is a nucleic acid, and whereby preferably the nucleic acid is binding to ghrelin.
    Type: Application
    Filed: August 1, 2003
    Publication date: November 16, 2006
    Inventors: Steffen Helmling, Dirk Eulberg, Christian Maasch, Sven Klussmann
  • Cgrp binding nucleic acids
    Publication number: 20060183700
    Abstract: The invention relates to an antagonist for CGRP and amylin, whereby the antagonist is a nucleic acid and said nucleic acid binds to CGRP or amylin. Said nucleic acid preferably comprises an L-nucleotide.
    Type: Application
    Filed: May 6, 2003
    Publication date: August 17, 2006
    Applicant: NOXXON Pharma AG
    Inventors: Axel Vater, Christian Maasch, Florian Jarosch, Mathias Bell, Steffen Helmling, Bernd Eschgfaller, Elisabeth Moyroud, Sandra Stark, Sven Klussmann, Thorsten Ruppert, Gregor Bahrenberg, Clemens Gillen, Klaus Schiene