Patents by Inventor Stella KNORR
Stella KNORR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10481054Abstract: The invention relates to a method for embedding a tissue sample into an embedding medium. In a first step the tissue sample is held in an intended orientation in a container by means of a holding element that presses the tissue sample against a base of the container. In a further step a liquid embedding medium that has a temperature above 64 degrees Celsius, in particular in the range from 65 degrees Celsius to 67 degrees Celsius, or a temperature of 66 degrees Celsius, is poured into the container, and the base of the container is cooled.Type: GrantFiled: September 1, 2016Date of Patent: November 19, 2019Assignee: Leica Biosystems Nussloch GmbHInventors: Florian Böhl, Ralf Eckert, Karin Flieger, Markus Berberich, Hermann Ulbrich, Stella Knorr, Andrew Guy
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Patent number: 10345203Abstract: An apparatus for holding a tissue sample including a retaining member having a first tissue engaging surface and at least one biasing element, the first tissue engaging surface being moveably attached to the retaining member by said biasing element; and a base having a second tissue engaging surface and configured to engage the retaining member to form an interior area with the first and second tissue engaging surfaces facing each other, wherein the at least one biasing element urges the first tissue engaging surface toward the second tissue engaging surface to retain the tissue sample therebetween in the interior area.Type: GrantFiled: April 6, 2016Date of Patent: July 9, 2019Assignee: Leica Biosystems Nussloch GmbHInventors: Stella Knorr, Andrew Guy, Ralf Eckert, Fiona Tarbet, Fernando Dias, Chris Ryan, Neil Sanut
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Publication number: 20170067804Abstract: The invention relates to a method for embedding a tissue sample into an embedding medium. In a first step the tissue sample is held in an intended orientation in a container by means of a holding element that presses the tissue sample against a base of the container. In a further step a liquid embedding medium that has a temperature above 64 degrees Celsius, in particular in the range from 65 degrees Celsius to 67 degrees Celsius, or a temperature of 66 degrees Celsius, is poured into the container, and the base of the container is cooled.Type: ApplicationFiled: September 1, 2016Publication date: March 9, 2017Inventors: Florian Böhl, Ralf Eckert, Karin Flieger, Markus Berberich, Hermann Ulbrich, Stella Knorr, Andrew Guy
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Publication number: 20160216176Abstract: An apparatus for holding a tissue sample including a retaining member having a first tissue engaging surface and at least one biasing element, the first tissue engaging surface being moveably attached to the retaining member by said biasing element; and a base having a second tissue engaging surface and configured to engage the retaining member to form an interior area with the first and second tissue engaging surfaces facing each other, wherein the at least one biasing element urges the first tissue engaging surface toward the second tissue engaging surface to retain the tissue sample therebetween in the interior area.Type: ApplicationFiled: April 6, 2016Publication date: July 28, 2016Applicant: Leica Biosystems Nussloch GmbHInventors: Stella KNORR, Andrew GUY, Ralf ECKERT, Fiona TARBET, Fernando DIAS, Chris RYAN, Neil SANUT
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Patent number: 9389154Abstract: An apparatus for holding a tissue sample including a retaining member having a first tissue engaging surface and at least one biasing element, the first tissue engaging surface being moveably attached to the retaining member by said biasing element; and a base having a second tissue engaging surface and configured to engage the retaining member to form an interior area with the first and second tissue engaging surfaces facing each other, wherein the at least one biasing element urges the first tissue engaging surface toward the second tissue engaging surface to retain the tissue sample therebetween in the interior area.Type: GrantFiled: March 11, 2014Date of Patent: July 12, 2016Assignee: Leica Biosystems Nussloch GmbHInventors: Stella Knorr, Andrew Guy, Ralf Eckert, Fiona Tarbet, Fernando Dias, Chris Ryan, Neil Sanut
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Patent number: 9304069Abstract: The invention relates to an apparatus for treatment of histological samples. The apparatus includes at least a working station, in which the sample gets into contact with a liquid reagent. Further, the apparatus includes a purification device, which blows off at least a part of the reagent adhering to the sample and/or the sample holding arrangement by means of a gas flow, or which sucks off at least a part of the reagent adhering to the sample and/or a sample holding arrangement.Type: GrantFiled: February 24, 2014Date of Patent: April 5, 2016Assignee: Leica Biosystems Nussloch GmbHInventors: Andrew Guy, Stella Knorr, Hermann Ulbrich
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Patent number: 9194776Abstract: The invention relates to a processor for working on histological samples. The processor has an inlet for the insertion of a fixing container, particularly a closed fixing container, with the samples located in the latter.Type: GrantFiled: March 11, 2014Date of Patent: November 24, 2015Assignee: Leica Biosystems Nussloch GmbHInventors: Ralf Eckert, Hermann Ulbrich, Stella Knorr, Graeme Robertson
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Patent number: 9097629Abstract: An apparatus for holding a tissue sample having a retaining member with a first tissue engaging surface and at least one biasing element. The first tissue engaging surface is moveably attached to the retaining member. The apparatus also has a base comprising a second tissue engaging surface which is configured to engage the retaining member to form an interior area with the first and second tissue engaging surfaces facing each other. The apparatus also has a retracting member connected to the retaining member which is configured to retract the first tissue engaging surface and compress the biasing element to form a gap between the tissue sample and one of the first tissue engaging surface and the second tissue engaging surface.Type: GrantFiled: March 11, 2014Date of Patent: August 4, 2015Assignee: Leica Biosystems Nussloch GmbHInventors: Florian Boehl, Stella Knorr, Peter Kotlarski, Graeme Robertson, Chris Ryan, Ian Sohn, Wilfred Bauwens, Fernando Dias
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Patent number: 9052256Abstract: A method for treating a tissue sample including placing at least one tissue sample on an cassette which has: a retaining member, a base and at least one biasing element; placing the at least one tissue sample in the tissue cassette; attaching the base and the retaining member to retain the tissue sample; processing the tissue sample in the tissue cassette with one or more solvents; and embedding the tissue sample in a paraffin to form an portion of paraffin in which the tissue sample is embedded in the tissue cassette, wherein the embedding comprises adding molten paraffin to the interior area of the tissue cassette and allowing the paraffin to become solid.Type: GrantFiled: March 11, 2014Date of Patent: June 9, 2015Assignee: Leica Biosystems Nussloch GmbHInventors: Stella Knorr, Andrew Guy, Ralf Eckert, Fiona Tarbet, Fernando Dias, Chris Ryan, Neil Sanut
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Publication number: 20140273084Abstract: An apparatus for holding a tissue sample having a retaining member with a first tissue engaging surface and at least one biasing element. The first tissue engaging surface is moveably attached to the retaining member. The apparatus also has a base comprising a second tissue engaging surface which is configured to engage the retaining member to form an interior area with the first and second tissue engaging surfaces facing each other. The apparatus also has a retracting member connected to the retaining member which is configured to retract the first tissue engaging surface and compress the biasing element to form a gap between the tissue sample and one of the first tissue engaging surface and the second tissue engaging surface.Type: ApplicationFiled: March 11, 2014Publication date: September 18, 2014Applicant: LEICA BIOSYSTEMS NUSSLOCH GMBHInventors: Florian BOEHL, Stella KNORR, Peter KOTLARSKI, Graeme ROBERTSON, Chris RYAN, Ian SOHN, Wilfred BAUWENS, Fernando DIAS
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Publication number: 20140273085Abstract: The invention relates to a processor for working on histological samples. The processor has an inlet for the insertion of a fixing container, particularly a closed fixing container, with the samples located in the latter.Type: ApplicationFiled: March 11, 2014Publication date: September 18, 2014Applicant: LEICA BIOSYSTEMS NUSSLOCH GMBHInventors: Ralf ECKERT, Hermann ULBRICH, Stella KNORR, Graeme ROBERTSON
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Publication number: 20140271407Abstract: An apparatus for holding a tissue sample including a retaining member having a first tissue engaging surface and at least one biasing element, the first tissue engaging surface being moveably attached to the retaining member by said biasing element; and a base having a second tissue engaging surface and configured to engage the retaining member to form an interior area with the first and second tissue engaging surfaces facing each other, wherein the at least one biasing element urges the first tissue engaging surface toward the second tissue engaging surface to retain the tissue sample therebetween in the interior area.Type: ApplicationFiled: March 11, 2014Publication date: September 18, 2014Applicant: LEICA BIOSYSTEMS NUSSLOCH GMBHInventors: Stella KNORR, Andrew GUY, Ralf ECKERT, Fiona TARBET, Fernando DIAS, Chris RYAN, Neil SANUT
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Publication number: 20140273078Abstract: The invention relates to an apparatus for treatment of histological samples. The apparatus includes at least a working station, in which the sample gets into contact with a liquid reagent. Further, the apparatus includes a purification device, which blows off at least a part of the reagent adhering to the sample and/or the sample holding arrangement by means of a gas flow, or which sucks off at least a part of the reagent adhering to the sample and/or a sample holding arrangement.Type: ApplicationFiled: February 24, 2014Publication date: September 18, 2014Applicant: Leica Biosystems Nussloch GmbHInventors: Andrew Guy, Stella KNORR, Hermann ULBRICH
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Publication number: 20140273083Abstract: A method for treating a tissue sample including placing at least one tissue sample on an cassette which has: a retaining member, a base and at least one biasing element; placing the at least one tissue sample in the tissue cassette; attaching the base and the retaining member to retain the tissue sample; processing the tissue sample in the tissue cassette with one or more solvents; and embedding the tissue sample in a paraffin to form an portion of paraffin in which the tissue sample is embedded in the tissue cassette, wherein the embedding comprises adding molten paraffin to the interior area of the tissue cassette and allowing the paraffin to become solid.Type: ApplicationFiled: March 11, 2014Publication date: September 18, 2014Applicant: LEICA BIOSYSTEMS NUSSLOCH GMBHInventors: Stella KNORR, Andrew GUY, Ralf ECKERT, Fiona TARBET, Fernando DIAS, Chris RYAN, Neil SANUT