Abstract: dsRNAi oligonucleotides can be used in methods for the treatment of NASH, preferably the advanced fibrotic and/or cirrhotic stages thereof, using dosage regimens comprising a loading phase followed by a maintenance phase.

Abstract: The invention is directed to a method for controlling a process of monitoring the position of at least a part of a patient's body (1) during a radiation treatment, the method comprising the following steps: a) providing an energy value which is dependent on the radiation energy applied to the patient's body (1); b) controlling the time at which the monitoring process is performed, in accordance with the energy value.

Abstract: The invention relates to a method for determining the position of an object moving within a body, wherein the body is connected to markers, a movement signal is determined based on the measured movement of the markers, images are taken from the object using a camera or detector, wherein the camera or detector is moved with respect to the object, it is determined from which direction or range of angles or segment the most images corresponding to a predefined cycle of the movement signal are taken, and using at least some or all of the images of the segment containing the most images for a specified movement cycle, an image of the object is reconstructed.

Abstract: The present invention refers to a data processing method for use in the field of radiation therapy and for determining a relative position between the position of the bony structure and a reference position at a monitoring time, the relative position being referred to as monitoring bone position, wherein an anatomical structure of a patient includes the bony structure and a treatment body part to be treated by at least one treatment beam of a treatment device, the reference position having a defined relative position with respect to an actual arrangement of at least one position of the at least one treatment beam; the data processing method being constituted to be performed by a computer and comprising the following steps: •providing CBCT image data describing a three-dimensional CBCT image of the bony structure, the CBCT image representing the bony structure at a pre-alignment time; •providing x-ray image data describing at least one two-dimensional x-ray image of the anatomical structure, the at least one t

Abstract: The present invention relates to a data processing method for use in the field of radiation therapy and for determining a position of a treatment body part relative to an actual arrangement of at least one position of a treatment beam issued by a treatment device, the position being called monitoring tissue position and the treatment body part being a soft tissue part of an anatomical structure of a patient; the data processing method being constituted to be performed by a computer and comprising the following steps: ? providing CBCT data describing a three-dimensional CBCT image of the anatomical structure, the three dimensional CBCT image representing the treatment body part and a bony structure in a relative position to each other, called tissue-bone pre-alignment position, at a point in time, called pre-alignment time; ? providing x-ray data describing information on a position of the bony structure, called monitoring bone position, relative to the actual arrangement at a point in, time during treatment,

Abstract: The present invention relates to a method for generating a complete medical image data set from an incomplete image data set, comprising the method steps of: providing a first image data set which represents an image of a first region of a body, including at least a part of the surface of the body, at a first point in time; providing a second, incomplete image data set which represents an image of a second region of the body at a second point in time, wherein the first region and the second region overlap; providing a third data set which represents the contour of the body in the form of points on the surface of the body, substantially at the second point in time; adapting the first image data set to the second image data set by taking into account the third data set; and accepting the adapted first image data set as a complete image data set.

Abstract: The invention is directed to a method for controlling a process of monitoring the position of at least a part of a patient's body (1) during a radiation treatment, the method comprising the following steps: a) providing an energy value which is dependent on the radiation energy applied to the patient's body (1); b) controlling the time at which the monitoring process is performed, in accordance with the energy value.

Abstract: The invention is directed to a method for controlling a process of monitoring the position of at least a part of a patient's body (1) during a radiation treatment, the method comprising the following steps: a) providing an energy value which is dependent on the radiation energy applied to the patient's body (1); b) controlling the time at which the monitoring process is performed, in accordance with the energy value.

Abstract: A patient positioning system for radiotherapy, comprising a device for positioning a patient within the framework of treatment planning, using image detection and/or carrying out radiation treatment, comprising a patient bed on which a patient is positioned, wherein means are provided by which the same bed may be arranged both on a planning couch for image detection within the framework of treatment planning as well as on a radiotherapy table, and by providing a reference means on the patient bed by which the position of the immobilized patient or of a marked radiation target is determined with respect to the patient bed. Within this framework, a corresponding method is also provided, as well as an adjusting means for the transport and the bed.

Abstract: The present invention refers to a data processing method for use in the field of radiation therapy and for determining a relative position between the position of the bony structure and a reference position at a monitoring time, the relative position being referred to as monitoring bone position, wherein an anatomical structure of a patient includes the bony structure and a treatment body part to be treated by at least one treatment beam of a treatment device, the reference position having a defined relative position with respect to an actual arrangement of at least one position of the at least one treatment beam; the data processing method being constituted to be performed by a computer and comprising the following steps: •providing CBCT image data describing a three-dimensional CBCT image of the bony structure, the CBCT image representing the bony structure at a pre-alignment time; •providing x-ray image data describing at least one two-dimensional x-ray image of the anatomical structure, the at least one t

Abstract: The present invention relates to a data processing method for use in the field of radiation therapy and for determining a position of a treatment body part relative to an actual arrangement of at least one position of a treatment beam issued by a treatment device, the position being called monitoring tissue position and the treatment body part being a soft tissue part of an anatomical structure of a patient; the data processing method being constituted to be performed by a computer and comprising the following steps: providing CBCT data describing a three-dimensional CBCT image of the anatomical structure, the three dimensional CBCT image representing the treatment body part and a bony structure in a relative position to each other, called tissue-bone pre-alignment position, at a point in time, called pre-alignment time; providing x-ray data describing information on a position of the bony structure, called monitoring bone position, relative to the actual arrangement at a point in, time during treatment, call

Abstract: A method for determining the position of a stent within a body, comprising the steps of: providing a 3D dataset of voxels representing a 3D image containing the stent; determining a starting position for the determination of the stent position; determining the axis of symmetry of the stent in the 3D dataset; determining a second dataset representing at least one image containing the stent in its present position; and determining the positional offset of the stent by image fusion using the 3D dataset and the second dataset and by penalizing a rotation around the axis of symmetry as compared to the starting position.

Abstract: The invention relates to a method for determining the position of an object moving within a body, wherein the body is connected to markers, a movement signal is determined based on the measured movement of the markers, images are taken from the object using a camera or detector, wherein the camera or detector is moved with respect to the object, it is determined from which direction or range of angles or segment the most images corresponding to a predefined cycle of the movement signal are taken, and using at least some or all of the images of the segment containing the most images for a specified movement cycle, an image of the object is reconstructed.

Abstract: The invention is directed to a method for controlling a process of monitoring the position of at least a part of a patient's body (1) during a radiation treatment, the method comprising the following steps: a) providing an energy value which is dependent on the radiation energy applied to the patient's body (1); b) controlling the time at which the monitoring process is performed, in accordance with the energy value.

Abstract: The invention relates to a method for determining the position of an object moving within a body, wherein the body is connected to markers, a movement signal is determined based on the measured movement of the markers, images are taken from the object using a camera or detector, wherein the camera or detector is moved with respect to the object, it is determined from which direction or range of angles or segment the most images corresponding to a pre-defined cycle of the movement signal are taken, and using at least some or all of the images of the segment containing the most images for a specified movement cycle, an image of the object is reconstructed.

Abstract: A patient positioning system for radiotherapy, comprising a device for positioning a patient within the framework of treatment planning, using image detection and/or carrying out radiation treatment, comprising a patient bed on which a patient is positioned, wherein means are provided by which the same bed may be arranged both on a planning couch for image detection within the framework of treatment planning as well as on a radiotherapy table, and by providing a reference means on the patient bed by which the position of the immobilized patient or of a marked radiation target is determined with respect to the patient bed. Within this framework, a corresponding method is also provided, as well as an adjusting means for the transport and the bed.

Abstract: The invention concerns a patient positioning system for radiotherapy, comprising a device for positioning a patient within the framework of treatment planning, using image detection and/or carrying out radiation treatment, comprising a patient bed (3, 42, 50) on which a patient is positioned, wherein means are provided by which the same bed (3, 42, 50) may be arranged both on a planning couch (8) for image detection within the framework of treatment planning as well as on a radiotherapy table (1, 44), and by providing a reference means (54) on the patient bed by which the position of the immobilised patient or of a marked radiation target is determined with respect to the patient bed (3, 42, 50). Within this framework, a corresponding method is also provided, as well as an adjusting means for the transport and the bed.

Abstract: A method for determining the position of a stent within a body, comprising the steps of: providing a 3D dataset of voxels representing a 3D image containing the stent; determining a starting position for the determination of the stent position; determining the axis of symmetry of the stent in the 3D dataset; determining a second dataset representing at least one image containing the stent in its present position; and determining the positional offset of the stent by image fusion using the 3D dataset and the second dataset and by penalizing a rotation around the axis of symmetry as compared to the starting position.

Abstract: The present invention relates to a method for generating a complete medical image data set from an incomplete image data set, comprising the method steps of: providing a first image data set which represents an image of a first region of a body, including at least a part of the surface of the body, at a first point in time; providing a second, incomplete image data set which represents an image of a second region of the body at a second point in time, wherein the first region and the second region overlap; providing a third data set which represents the contour of the body in the form of points on the surface of the body, substantially at the second point in time; adapting the first image data set to the second image data set by taking into account the third data set; and accepting the adapted first image data set as a complete image data set.

Abstract: A patient positioning system for radiotherapy, comprising a device for positioning a patient within the framework of treatment planning, using image detection and/or carrying out radiation treatment, comprising a patient bed on which a patient is positioned, wherein means are provided by which the same bed may be arranged both on a planning couch for image detection within the framework of treatment planning as well as on a radiotherapy table, and by providing a reference means on the patient bed by which the position of the immobilized patient or of a marked radiation target is determined with respect to the patient bed. Within this framework, a corresponding method is also provided, as well as an adjusting means for the transport and the bed.