Patents by Inventor Stephan Korner
Stephan Korner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240083473Abstract: A mounting interface for attaching supporting components to a buffer of a rail vehicle. The interface has a mounting body with a component fastening region and an attachment region that is different therefrom. The component fastening region is equipped with fastening elements and/or bores for attaching the components. The attachment region is formed in such a manner that it can be fastened to at least one fastening point at a front side of a buffer flange using screws. There is also described a buffer system and a rail vehicle with such a mounting interface.Type: ApplicationFiled: December 6, 2021Publication date: March 14, 2024Inventors: Stephan Drexler, Marcus Körner, Hannes Peer
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Publication number: 20200298234Abstract: The present disclosure relates to a method for isolating a biological target material from a liquid sample in a multiwell plate using magnetic particles, wherein high efficiency and low elution volumes are achieved by specific movements of the multiwell plate and a magnetic separation plate in relation to each other. Also disclosed is a pre-analytical system suitable for carrying out the method.Type: ApplicationFiled: June 8, 2020Publication date: September 24, 2020Inventors: Stephan KORNER, Emad SAROFIM, Goran SAVATIC, Marko SIMIC
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Publication number: 20190156943Abstract: A computer implemented method for localizing handheld analytical devices in a point of care environment is presented. The method comprises associating a location identifier to a plurality of locations within the point of care environment and storing the location identifier into a database, at each of the plurality of locations, capturing signal patterns using signal receiver(s) of the handheld analytical devices, storing all signal patterns captured in a database, capturing a current signal pattern using signal receiver(s) of a handheld analytical device to be localized, and providing a descriptive localization by a control unit indicative of its position relative to one or more of the plurality of locations within the point of care environment associated with one or more signal pattern(s) stored in the database matching the current signal pattern.Type: ApplicationFiled: November 1, 2018Publication date: May 23, 2019Applicant: Roche Diagnostics Operations, Inc.Inventors: Gerrit Kocherscheidt, Stephan Korner, Ulrich Porsch, Chris Steinert, Hermann Hofstetter
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Patent number: 10251589Abstract: A system for withdrawing blood from a body part that avoids formation of a drop of blood on the skin surface of the body part after blood removal. The system includes a collecting unit to withdraw blood, a lancing member configured for insertion into the body part and having a capillary to collect blood, and a pressure piece configured to apply pressure to the body part and having an actuator operably connected thereto. The pressure piece is movable relative to a support configured to exert pressure on the body part, and the actuator is configured to reduce the compressive force of the pressure piece after removing an amount of blood, whereby forming a drop of blood on the skin surface of the body part can be avoided.Type: GrantFiled: July 22, 2016Date of Patent: April 9, 2019Assignee: ROCHE DIABETES CARE, INC.Inventors: Stephan Korner, Rainer Jaeggi, Patrick Griss, Emad Sarofim, Irio Giuseppe Calasso
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Publication number: 20180080949Abstract: A method is presented. The method includes receiving at least one order, generating one or more optimization problem instances using one or more resource descriptions of automated laboratory equipment, one or more protocol descriptions of the automated laboratory equipment, an objective function and the at least one order. The method further includes providing the one or more optimization problem instances as input to a constraint optimization solver and processing the one or more optimization problem instances by the constraint optimization solver to generate the schedule of operations to carry out the at least one order on the automated laboratory equipment.Type: ApplicationFiled: September 14, 2017Publication date: March 22, 2018Applicant: Roche Diagnostics Operations, Inc.Inventors: Friedrich Jost, Stephan Korner, Rijk Edwin Oosterbroeck, Gabriele Piero Janner
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Publication number: 20160367176Abstract: A system for withdrawing blood from a body part that avoids formation of a drop of blood on the skin surface of the body part after blood removal. The system includes a collecting unit to withdraw blood, a lancing member configured for insertion into the body part and having a capillary to collect blood, and a pressure piece configured to apply pressure to the body part and having an actuator operably connected thereto. The pressure piece is movable relative to a support configured to exert pressure on the body part, and the actuator is configured to reduce the compressive force of the pressure piece after removing an amount of blood, whereby forming a drop of blood on the skin surface of the body part can be avoided.Type: ApplicationFiled: July 22, 2016Publication date: December 22, 2016Inventors: Stephan Korner, Rainer Jaeggi, Patrick Griss, Emad Sarofim, Irio Giuseppe Calasso
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Patent number: 9442109Abstract: Centrifugal force based microfluidic systems for the automated analysis of fluids involving the use of magnetically responsive particles and methods thereof are disclosed. A magnet is fixed to a supporting device of the system in correspondence to a retention zone of the system so as to rotate therewith and to generate a magnetic field which magnetically manipulates the magnetically responsive particles contained in a reaction chamber of the system.Type: GrantFiled: May 17, 2010Date of Patent: September 13, 2016Assignee: Roche Diagnostics Operations, Inc.Inventors: Rijk Edwin Oosterbroek, Mario Curcio, Stephan Korner, Brigitte Niederberger
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Patent number: 9414774Abstract: A system and method for carrying out the withdrawal of body fluid with as little body fluid as possible visible to the user at the end of the process. The present invention provides a pressure piece for exerting pressure on a body part. The pressure piece is moved relative to a support for the body part, and in the final phase of fluid withdrawal, the compressive or resistive force of the pressure piece on the body part is reduced in order to avoid the escape of body fluid from the puncture site. The support results in a defined positioning of the body part that rests against it for the lancing process, whereas the relative movement of the pressure piece enables an additional increase in pressure and thus an improved collection of fluid.Type: GrantFiled: October 9, 2006Date of Patent: August 16, 2016Assignee: Roche Diabetes Care, Inc.Inventors: Stephan Korner, Rainer Jaeggi, Patrick Griss, Emad Sarofim, Irio Guiseppe Calasso
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Patent number: 9063038Abstract: A device for sampling, transporting and/or disposal of fluid media in the nl and ?l-range comprises a substrate with an open or closed capillary-like groove or channel respectively, the substrate with the open or closed groove or capillary respectively is bent or arcuated at least at one location. The substrate comprises at least one end into which the open or closed capillary-like groove or channel respectively is extended, which end is shaped according to its application or use as e.g. needle-like, straight-lined cut, tip-like, at least most half circle-shape, rounded, etc.Type: GrantFiled: March 13, 2013Date of Patent: June 23, 2015Assignee: Roche Diagnostics Operations, Inc.Inventors: Carlo Effenhauser, Patrick Griss, Stephan Korner, Emad Sarofim
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Publication number: 20140109861Abstract: A piston for an internal combustion engine may include a piston head and a piston skirt. The piston skirt may have piston bosses provided with boss bores. The piston bosses may be connected to each other at running surfaces. The running surfaces may be provided at least partially with a coating which is sprayed using a cold gas method. The material of the coating may be selected from the group comprising at least one of nickel, iron, copper, nickel-based alloys, iron-based alloys, copper-nickel-tin-based alloys and copper-tin-silver-based alloys.Type: ApplicationFiled: October 19, 2012Publication date: April 24, 2014Applicant: Mahle International GmbHInventors: Stephan Korner, Wolfgang Schlenther, Cedric Dobua
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Patent number: 8636675Abstract: The present invention provides a method and a device for piercing a body part and determining whether a sufficient volume of blood has been withdrawn. A lancing element is rapidly inserted into a body part in a forward phase and retracted quickly to a lesser puncturing depth. Subsequently, the lancing element is retracted slower than during the first retraction movement and the distance retracted during the second retraction is shorter than the first retraction movement. During the second retraction movement, body fluid is collected in a collection phase by a capillary structure of the lancing element. Contact between the lancing element and the body fluid is detected after the forward phase at the beginning and the end of a waiting period.Type: GrantFiled: October 8, 2010Date of Patent: January 28, 2014Assignee: Roche Diagnostics Operations, Inc.Inventors: Heinz-Michael Hein, Reto Abt, Stephan Korner, Irio Giuseppe Calasso, Emad Sarofim, Patrick Griss, Rainer Jaeggi
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Patent number: 8420024Abstract: A device for sampling, transporting and/or disposal of fluid media in the nl and ?l-range comprises a substrate with an open or closed capillary-like groove or channel respectively, the substrate with the open or closed groove or capillary respectively is bent or arcuated at least at one location. The substrate comprises at least one end into which the open or closed capillary-like groove or channel respectively is extended, which end is shaped according to its application or use as e.g. needle-like, straight-lined cut, tip-like, at least most half circle-shape, rounded, etc.Type: GrantFiled: April 4, 2012Date of Patent: April 16, 2013Assignee: Roche Diagnostics Operations, Inc.Inventors: Stephan Korner, Patrick Griss, Emad Sarofim, Carlo Effenhauser
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Publication number: 20120230885Abstract: A device for sampling, transporting and/or disposal of fluid media in the nl and ?l-range comprises a substrate with an open or closed capillary-like groove or channel respectively, the substrate with the open or closed groove or capillary respectively is bent or arcuated at least at one location. The substrate comprises at least one end into which the open or closed capillary-like groove or channel respectively is extended, which end is shaped according to its application or use as e.g. needle-like, straight-lined cut, tip-like, at least most half circle-shape, rounded, etc.Type: ApplicationFiled: April 4, 2012Publication date: September 13, 2012Inventors: Stephan Korner, Patrick Griss, Emad Sarofim, Carlo Effenhauser
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Patent number: 8241566Abstract: A device for sampling, transporting and/or disposal of fluid media in the nl and ?l-range comprises a substrate with and open or closed capillary-like groove or channel respectively, the substrate with the open or closed groove or capillary respectively is bent or arcuated at least at one location. The substrate comprises at least one end into which the open closed capillary-like groove or channel respectively is extended, which end is shaped according to its application or use as e.g. needle-like, straight-lined cut, tip-like, at least most half circle-shape, rounded, etc.Type: GrantFiled: November 22, 2005Date of Patent: August 14, 2012Assignee: Roche Diagnostics Operations, Inc.Inventors: Stephan Korner, Patrick Griss, Emad Sarofim, Carlo Effenhauser
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Publication number: 20110136109Abstract: A system and method for cycling liquid samples through a series of temperature excursions are disclosed. Provided are open-top reaction vessels for containing the samples, which may be enclosed by one or more covers. A temperature-controlled block for generating or adsorbing heat is coupled thermally to the reaction vessels. A detection arrangement is disposed in an emission beam path to detect radiation emitted from the samples through the covers. A heating arrangement for generating heat includes a heating element that is both disposed between the reaction vessels and the detection arrangement and coupled thermally to the covers. The heating element includes an optically transparent substrate provided with one or more opaque heating lines, the heating lines being disposed in the emission beam path in a manner to obtain a predetermined minimum optical transmission of the heating element. A controller, set up to control cycling of the samples, is provided.Type: ApplicationFiled: December 8, 2010Publication date: June 9, 2011Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.Inventors: Andreas Drechsler, Emad Sarofim, Claudio Cherubini, Stephan Korner
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Publication number: 20110124128Abstract: Centrifugal force based microfluidic systems for the automated analysis of fluids involving the use of magnetically responsive particles and methods thereof are disclosed. A magnet is fixed to a supporting device of the system in correspondence to a retention zone of the system so as to rotate therewith and to generate a magnetic field which magnetically manipulates the magnetically responsive particles contained in a reaction chamber of the system.Type: ApplicationFiled: May 17, 2010Publication date: May 26, 2011Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.Inventors: Rijk Edwin Oosterbroek, Mario Curcio, Stephan Korner, Brigitte Niederberger
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Publication number: 20110028862Abstract: The present invention provides a method and a device for piercing a body part and determining whether a sufficient volume of blood has been withdrawn. A lancing element is rapidly inserted into a body part in a forward phase and retracted quickly to a lesser puncturing depth. Subsequently, the lancing element is retracted slower than during the first retraction movement and the distance retracted during the second retraction is shorter than the first retraction movement. During the second retraction movement, body fluid is collected in a collection phase by a capillary structure of the lancing element. Contact between the lancing element and the body fluid is detected after the forward phase at the beginning and the end of a waiting period.Type: ApplicationFiled: October 8, 2010Publication date: February 3, 2011Inventors: Heinz-Michael Hein, Reto Abt, Stephan Korner, Irio Giuseppe Calasso, Emad Sarofim, Patrick Griss, Rainer Jaeggi
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Patent number: 7833172Abstract: The present invention provides a method and a device for piercing a body part and determining whether a sufficient volume of blood has been withdrawn. A lancing element is rapidly inserted into a body part in a forward phase and retracted quickly to a lesser puncturing depth. Subsequently, the lancing element is retracted slower than during the first retraction movement and the distance retracted during the second retraction is shorter than the first retraction movement. During the second retraction movement, body fluid is collected in a collection phase by a capillary structure of the lancing element. Contact between the lancing element and the body fluid is detected after the forward phase at the beginning and the end of a waiting period.Type: GrantFiled: October 7, 2007Date of Patent: November 16, 2010Assignee: Roche Diagnostics Operations, Inc.Inventors: Heinz-Michael Hein, Reto Abt, Stephan Korner, Irio Giuseppe Calasso, Emad Sarofim, Patrick Griss, Rainer Jaeggi
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Publication number: 20090093735Abstract: The test unit for analyzing body fluids such as blood comprises a collecting element which has a microfluidic collecting area for the body fluid, and a test element which can be brought into fluidic connection with the collecting area by deflecting a transfer part of the collecting element in order to transfer body fluid. The transfer part is pre-tensioned against a holding-down device and the deflection of the transfer part towards the test element can be triggered by releasing the holding-down device.Type: ApplicationFiled: September 29, 2008Publication date: April 9, 2009Inventors: Stephan Korner, Brigitte Niederberger, Denise Schnarrwyler
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Publication number: 20080294064Abstract: In the case of a disposable lancing element for collecting body fluid through the skin comprising a support and a lancing member which distally projects therefrom and can pierce the skin in a lancing movement, it is proposed that a pretensioning means which tightens the skin in the area of the puncture site is arranged on the support and has a contact member which impacts the skin laterally from the lancing member during the lancing movement.Type: ApplicationFiled: May 9, 2008Publication date: November 27, 2008Inventors: Irio Calasso, Oliver Bruendler, Michael Glauser, Hans-Peter Wahl, Stephan Korner