Patents by Inventor Stephan Uebel

Stephan Uebel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PEPTIDES AS INHIBITORS OF FIBROTIC MATRIX ACCUMULATION
    Publication number: 20220267378
    Abstract: The present invention relates to peptides that inhibit overproduction and/or excess accumulation of extracellular matrix in an organ or tissue. The inventive peptides have the general sequence Xa-Leu-Gln-Gly-Xb (SEQ ID NO: 1), wherein Xa is selected from Pro-Gly, Gly and Ac-Gly and Xb is selected from Glu and Glu-NH2, and are able of inhibit overproduction and excess accumulation of extracellular matrix in an organ or tissue both as linear peptides and as cyclic peptides.
    Type: Application
    Filed: July 28, 2020
    Publication date: August 25, 2022
    Inventors: Inaam Nakchbandi, Stefan Hamelmann, Stephan Uebel
  • Elastin peptide fingerprints and analysis methods for MMP12 related to COPD
    Patent number: 8012692
    Abstract: Methods for producing and using protein/peptide fingerprints, allowing identification and investigation of disease-associated proteins/peptides that can be linked to specific drug targets, or to specific drug target combinations. The methods are particularly useful for studies relating to Chronic Obstructive Pulmonary Disease (COPD), especially for the enzyme MMP12.
    Type: Grant
    Filed: September 24, 2004
    Date of Patent: September 6, 2011
    Assignee: AstraZeneca AB
    Inventors: Per Broberg, Thomas Fehniger, György Marko-Varga, Stephan Uebel
  • Peptide Fingerprint from the Degradation of Elastin by HNE
    Publication number: 20100203565
    Abstract: Methods for producing and using protein/peptide fingerprints, derived from elastin degraded by the enzyme human Neutrophil Elastase (HNE), allowing identification and investigation of disease-associated proteins/peptides that can be linked to specific drug targets, or to specific drug target combinations. The methods are particularly useful for studies relating to Chronic Obstructive Pulmonary Disease (COPD).
    Type: Application
    Filed: March 20, 2006
    Publication date: August 12, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Per Broberg, Thomas Fehniger, Claes Lindberg, Gyorgy Marko-Varga, Stephan Uebel
  • Elastin peptide fingerprints and analysis methods for mmp12 related to copd
    Publication number: 20060292631
    Abstract: Methods for producing and using protein/peptide fingerprints, allowing identification and investigation of disease-associated proteins/peptides that can be linked to specific drug targets, or to specific drug target combinations. The methods are particularly useful for studies relating to Chronic Obstructive Pulmonary Disease (COPD), especially for the enzyme MMP12.
    Type: Application
    Filed: September 24, 2004
    Publication date: December 28, 2006
    Inventors: Per Broberg, Thomas Fehniger, Gyorgy Marko-Varga, Stephan Uebel