Patents by Inventor Stephanie Hartsel

Stephanie Hartsel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polynucleotide synthesis labeling chemistry
    Patent number: 8026349
    Abstract: Methods and compositions for making nucleoside phosphoramidites and nucleic acids, including mono-, di-, and polynucleotides, comprising a linker covalently attached to a levulinyl moiety are provided. A levulinyl-protected linking moiety affords an orthogonal approach to modifying a polynucleotide during or after solid phase synthesis with a molecule of interest, for example, a conjugate or a dye.
    Type: Grant
    Filed: August 18, 2005
    Date of Patent: September 27, 2011
    Assignee: Dharmacon, Inc.
    Inventors: Stephanie A. Hartsel, Robert J. Kaiser, Michael O. Delaney
  • Novel Polynucleotide Synthesis Labeling Chemistry
    Publication number: 20080009612
    Abstract: Methods and compositions for making nucleoside phosphoramidites and nucleic acids, including mono-, di-, and polynucleotides, comprising a linker covalently attached to a levulinyl moiety are provided. A levulinyl-protected linking moiety affords an orthogonal approach to modifying a polynucleotide during or after solid phase synthesis with a molecule of interest, for example, a conjugate or a dye.
    Type: Application
    Filed: August 18, 2005
    Publication date: January 10, 2008
    Inventors: Stephanie Hartsel, Robert Kaiser, Michael Delaney
  • Highly functional short hairpin RNA
    Publication number: 20060223777
    Abstract: The present invention provides improved hairpin and fractured hairpin constructs for use in gene silencing through the RNA interference pathway. An exemplary short hairpin polynucleotide for use in gene silencing can include a polynucleotide having from about 42 nucleotides to about 106 nucleotides configured for being processed by Dicer. The polynucleotide can include a first region having from about 19 to about 35 nucleotides, a loop region coupled to the first region, the loop region having from about 4 to about 30 nucleotides, and a second region having from about 19 to about 35 nucleotides and having at least about 80% complementarity to the first region. Optionally, one of the first region or second region can have an overhang having less than about 6 nucleotides. Also, the short hairpin can be formed of a plurality of polynucleotides that cooperate to form a hairpin structure.
    Type: Application
    Filed: March 28, 2006
    Publication date: October 5, 2006
    Inventors: Annaleen Vermeulen, Angela Reynolds, Jon Karpilow, Devin Leake, Xiaoqin Cheng, Stephanie Hartsel, Anastasia Khvorova
  • Exercise equipment for sit-ups
    Patent number: 6126581
    Abstract: A piece of exercise equipment designed to shape and strengthen the abdominal muscles while providing comfort, proper positioning of the upper body, and the ability to increase intensity and effectiveness of the exercise over time. The device has a curved headpiece in which to accommodate the back of the head, and extensions which maintain arm position during exercise.
    Type: Grant
    Filed: October 16, 1998
    Date of Patent: October 3, 2000
    Inventor: Stephanie A. Hartsel