Abstract: A rotatable chip-on-tip endoscope is configured to be operated with a single hand, with the palm holding the body of the device and one or two fingers operating a distal rotatable end of the handle that carries the needle. The needle is small in diameter, preferably less than 2.5 mm at its largest end. As the tip is rotated to view more widely in a patient's joint, for example, video processing electronics correct rotational orientation in real time to present a consistent moving image on a monitor.

Abstract: A laryngeal mask airway device that establishes pulmonary breathing of a patient and receives a endotracheal tube includes an airway tube with a distal end mask, the mask having a peripheral cuff to form a seal around the patient's laryngeal inlet. An endoscope channel is formed separately from the airway tube so as to receive an endoscope capable of illuminating and viewing the laryngeal anatomy. The endoscope channel may be closed by a transparent viewing window at a distal end. In an embodiment the endoscope channel has a mechanical asymmetry to ensure proper insertion of the visualizaton stylet. The airway device may include an additional channel for monitoring pressure in the laryngeal region. A visualization stylet to be used with the airway device is preferably connected wirelessly to display equipment. The airway device can also include markings to be imaged by the visualization stylet during insertion, for correct placement and to assess dimensions of a patient's anatomical features.

Abstract: A clip for use in carpal tunnel surgery and similar surgeries has two separate clip sections, each with a proximal end that snaps together with the opposing proximal end of the other section, to make an assembled clip with a space between the sections except at proximal ends. At least one of the clip sections can be configured as a dilator, with a tapered distal end and without sharp edges. The two clip sections form endoscope and live channels to receive a viewing endoscope and a knife, inserted through the proximal end of the assembled clip device. Illumination is provided, either within the clip or from the scope of another inserted device, to enable viewing through the endoscope during a procedure. An embodiment of the clip device is formed with a rotation hub, such that the two clip sections can be swung apart or used together in a surgical procedure.

Abstract: A Veress needle is modified to receive a forward-looking miniature videoscope through the lumen of an insufflation tube of the Veress needle. The modified instrument enables direct viewing of progress of the instrument through tissue to the peritoneal cavity of a patient, for proper location of the needle and insufflation of the cavity via the needle. The videoscope has an elongated shaft of smaller diameter than the lumen of the insufflation tube for passage of insufflation gas with the scope in place. In another embodiment a needle is fitted with a miniature videoscope to provide the same function, with the needle's lumen serving as an insufflation tube.

Abstract: A Veress needle is modified to receive a forward-looking miniature videoscope through the cannula of an insufflation tube of the Veress needle. The modified instrument enables direct viewing of progress of the instrument through tissue to the peritoneal cavity of a patient, for proper location of the needle and insufflation of the cavity via the needle. The videoscope has an elongated shaft of smaller diameter than the cannula of the insufflation tube for passage of insufflation gas with the scope in place. In another embodiment a needle is fitted with a miniature videoscope to provide the same function, with the needle's cannula serving as an insufflation tube.

Abstract: A Veress needle is modified to receive a forward-looking miniature videoscope through the cannula of an insufflation tube of the Veress needle. The modified instrument enables direct viewing of progress of the instrument through tissue to the peritoneal cavity of a patient, for proper location of the needle and insufflation of the cavity via the needle. The videoscope has an elongated shaft of smaller diameter than the cannula of the insufflation tube for passage of insufflation gas with the scope in place. In another embodiment a needle is fitted with a miniature videoscope to provide the same function, with the needle's cannula serving as an insufflation tube.

Abstract: A Veress needle is modified to receive a forward-looking miniature videoscope through the cannula of an insufflation tube of the Veress needle. The modified instrument enables direct viewing of progress of the instrument through tissue to the peritoneal cavity of a patient, for proper location of the needle and insufflation of the cavity via the needle. The videoscope has an elongated shaft of smaller diameter than the cannula of the insufflation tube for passage of insufflation gas with the scope in place. In another embodiment a needle is fitted with a miniature videoscope to provide the same function, with the needle's cannula serving as an insufflation tube.

Abstract: The invention concerns observation, measurement and analysis of a person's eye movements while viewing a screen, for purposes of evaluating brain health, eye coordination or level of ability of a person for various pursuits such as sports.

Abstract: Provided herein are nanostructure-based sequencing methods and systems.

Abstract: Provided herein are nanostructure-based sequencing methods and systems. Such methods and systems include contacting an immobilized RNA polymerase with a double-stranded target nucleic acid molecule under sequencing conditions, where the sequencing conditions include the presence of four nucleoside triphosphates, where one of the nucleoside triphosphates is present in a rate-limiting amount; detecting the movement of the target nucleic acid molecule and/or one or more nascent strand(s) through, on or over a nanostructure; repeating the contacting and detecting steps a plurality of times; and determining the sequence of the target nucleic acid molecule based, sequentially, on the presence or absence of a change in the movement in the presence of the at least one nucleoside triphosphate.

Abstract: A Veress needle is modified to receive a forward-looking miniature videoscope through the cannula of an insufflation tube of the Veress needle. The modified instrument enables direct viewing of progress of the instrument through tissue to the peritoneal cavity of a patient, for proper location of the needle and insufflation of the cavity via the needle. The videoscope has an elongated shaft of smaller diameter than the cannula of the insufflation tube for passage of insufflation gas with the scope in place. In another embodiment a needle is fitted with a miniature videoscope to provide the same function, with the needle's cannula serving as an insufflation tube.

Abstract: Provided herein are nanostructure-based sequencing methods and systems.

Abstract: Endoscopes, particularly videoscopes, of small size and profile are applied to various medical devices such as intravascular catheters and feeding tubes. The endoscopes are of high flexibility, good resolution and low cost so as to be disposable after use.

Abstract: An apparatus, including a light detecting means, determines the actual position of an optical fiber array having one or more, but fewer than all, short fibers by detecting light transmitted through the short fiber(s) as a laser beam is horizontally and/or vertically scanned across the proximal fiber end(s). The fiber array is attached to an alignment block that facilitates delivery of the array to an accurate positioning means comprising two substantially parallel dowels.

Abstract: An apparatus and method for accurately and reproducibly locating a planar array of optical fibers in space are disclosed. A single acousto-optic modulator is used to accurately and substantially-simultaneously deflect multiple beams of different-wavelength radiation energy to each of said accurately-positioned optical fibers. Both aspects of the invention can be used in an apparatus and method for removing occlusions from vessels, as previously disclosed.

Abstract: A fiber optic radiation transmission system is provided in which an optical fiber and a radiation source are connected to establish optical communication therebetween. Additionally, a connecting system is provided for connecting an optical fiber and a radiation source such that optical communication is established therebetween. The systems include a connector which carries the optical fiber therein. The connector is extendable within the system toward the radiation source to bring the optical fiber into optical communication with the radiation source. More particularly, the systems are configured in such a way that when the connector is extended sufficiently within the system, it seats the optical fiber relative to the radiation source under bias, thereby establishing a reliable optical connection. Once the optical connection is thus established, the connector engages a connection port associated with the radiation source to secure the system in a fully connected configuration appropriate for use.

Abstract: A fiber optic radiation transmission system is provided in which an optical fiber and a radiation source are connected to establish optical communication therebetween. Additionally, a connecting system is provided for connecting an optical fiber and a radiation source such that optical communication is established therebetween. The systems include a connector which carries the optical fiber therein. The connector is extendable within the system toward the radiation source to bring the optical fiber into optical communication with the radiation source. More particularly, the systems are configured in such a way that when the connector is extended sufficiently within the system, it seats the optical fiber relative to the radiation source under bias, thereby establishing a reliable optical connection. Once the optical connection is thus established, the connector engages a connection port associated with the radiation source to secure the system in a fully connected configuration appropriate for use.

Abstract: A fiber optic radiation transmission system is provided in which an optical fiber and a radiation source are connected to establish optical communication therebetween. Additionally, a connecting system is provided for connecting an optical fiber and a radiation source such that optical communication is established therebetween. The systems include a connector which carries the optical fiber therein. The connector is extendable within the system toward the radiation source to bring the optical fiber into optical communication with the radiation source. More particularly, the systems are configured in such a way that when the connector is extended sufficiently within the system, it seats the optical fiber relative to the radiation source under bias, thereby establishing a reliable optical connection. Once the optical connection is thus established, the connector engages a connection port associated with the radiation source to secure the system in a fully connected configuration appropriate for use.