Abstract: Disclosed herein include antibodies or fragments thereof having specificity to a sarbecovirus spike protein. Also provided are compositions, methods, and kits for using said antibodies or fragments thereof for preventing or treating, for example a coronavirus infection.

Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

Abstract: An inexpensive, high performance error detecting and correcting system capable of handling multiple errors with high throughput. Digital data is provided to a reconfigurable decoder which is initially set for a low level of correction and a high throughput. On detection of an error, a signal is generated which is used to dynamically reconfigure the decoder. The decoder is reconfigured at a higher correction level. The data is then reprocessed through the reconfigured decoder. In a specific implementation, the invention uses a Blahut decoder. N and K values to reconfigure the decoder are provided by a microprocessor. The invention contemplates use of an encoder operating at the highest level of correction required. Use of an initial low level of correction provides for a high throughput. Reconfigurability allows for high corrective power and associated lower throughput only when necessary.

Abstract: A method and apparatus which first calculates track to track skew in a tape device and then uses the results of that calculation to adjust the windows for detection of sync and resync characters. The system makes use of global circuitry which adjusts the sync and resync windows for all tracks based upon the skew calculation. In the case of the windows used for detecting resyncs, when skew is determined to be large, the global resync window must span a larger time period to account for the skew in detecting resync marks. Conversely, when there is little or no skew present, the windows for resync detection can be narrowed. Normally, the track logic utilizes its own local windows to detect resyncs. If a track misses a resync, however, it must use the global resync window to determine the next resync location. Once the tracks are resynchronized, control can return to local track circuitry to maintain synchronization.

Abstract: A method and system for accurately reading and storing data as multiple data blocks on a removable data storage medium mounted within a data storage system. Each data block includes an initial acquisition data character and multiple diverse synchronization characters/bursts and adjacent data blocks are separated by a unique interblock gap character. A multimodal interblock gap character detection circuit is provided which may operate in a normal mode of operation or a stringent mode of operation, wherein an enhanced degree of certainty is required for detection of the interblock gap character. A predicted time window of occurrence for a next interblock gap character is generated in response to detection of an initial acquisition data character and at least one synchronization character within a data block. Additionally, a global clock count signal based upon multiple track outputs is generated each time a resynchronization burst is encountered.

Abstract: A data storage system has error detecting and correcting system having three error codes. The data are arranged logically as a three-dimensional array consisting of a plurality of logically rectangular blocks of data. Each block of data has columns and rows of data. A first error code that corrects errors creates a first redundancy in each of the columns. A like-positioned block row of data in each of the blocks constitutes an array row of data. The array rows are grouped into sets of array rows, the number of array rows in each set vary inversely with a number of tracks of a record medium that concurrently receive the data for recording. Each set of data are recorded serially by bit in respective tracks of the tape record medium. Before recording, the block rows are logically rotated (end-around shifted) within each of the array rows.

Abstract: A method and apparatus which first calculates track to track skew in a tape device and then uses the results of that calculation to adjust the windows for detection of sync and resync characters. The system makes use of global circuitry which adjusts the sync and resync windows for all tracks based upon the skew calculation. In the case of the windows used for detecting resyncs, when skew is determined to be large, the global resync window must span a larger time period to account for the skew in detecting resync marks. Conversely, when there is little or no skew present, the windows for resync detection can be narrowed. Normally, the track logic utilizes its own local windows to detect resyncs. If a track misses a resync, however, it must use the global resync window to determined the next resync location. Once the tracks are resynchronized, control can return to local track circuitry to maintain synchronization.

Abstract: Pointer control logic for error correcting codes includes a set of registers the contents of which are rotated whenever data from a track with a pointer are processed. In that manner, a given one register always contains pointer data for the track under consideration (if that track has a pointer). The pointer control logic includes programmable initializing values to stress write operations as desired. Further, the logic contains multiple and programmable pointer dropping thresholds so that pointer registers can be candidates for dropping dependent on the type of error encountered. Provision is made for extending pointer life when errors are encountered, registers are full, and no register has dropped below the pointer dropping threshold.

Abstract: A record medium, such as a magnetic tape, optical disk, magnetic disk, and the like stores data signals and error redundancy signals. Resynchronization signals are interleaved between the recorded signals such that the error redundancy signals are usable to correct signals recorded between such interposed resynchronization signals wherein no error redundancy signals are recorded. Error pointing redundancy signals are recorded between all of the resynchronization signals for pointing to signals in error for enhancing the error correction. Such error pointing signals can be cyclic redundancy check (CRC) signals. Controls for taking advantage of the above-described arrangement are also described. Reframing and clock synchronization controls are also disclosed.

Abstract: A record medium, such as a magnetic tape, optical disk, magnetic disk, and the like stores data signals and error redundancy signals. Resynchronization signals are interleaved between the recorded signals such that the error redundancy signals are usable to correct signals recorded between such interposed resynchronization signals wherein no error redundancy signals are recorded. Error pointing redundancy signals are recorded between all of the resynchronization signals for pointing to signals in error for enhancing the error correction. Such error pointing signals can be cyclic redundancy check (CRC) signals. Controls for taking advantage of the above-described arrangement are also described. Reframing and clock synchronization controls are also disclosed.