Abstract: The present disclosure provides a catheter pump system comprising components configured to prevent blood from entering the catheter pump system. The catheter pump system includes a septum including a moisture absorbing material and/or an impeller assembly including an impeller shaft coated on an inner or an outer surface with a clot activator.

Abstract: In various embodiments, a catheter pump is disclosed herein. The catheter pump can include an elongated catheter body having a distal portion including an expandable cannula having an inlet and an outlet. An impeller assembly can include an impeller shaft and one or more blades. The impeller blades can draw blood into the expandable cannula when rotated. Further, an expandable support can have a mounting portion. The mounting portion can have a cylindrical member disposed on the impeller shaft and can include an enlarged distal portion at a distal end of the impeller shaft and a nose member. Further, a re-sealable member can be disposed in the enlarged distal portion of the cylindrical member and can have a path through the re-sealable member through which a guidewire can be positioned. Further, the nose member can have an aperture distal of the re-sealable member for passage of the guidewire.

Abstract: In various embodiments, a catheter pump is disclosed herein. The catheter pump can include an elongated catheter body having a distal portion including an expandable cannula having an inlet and an outlet. An impeller assembly can include an impeller shaft and one or more blades. The impeller blades can draw blood into the expandable cannula when rotated. Further, an expandable support can have a mounting portion disposed on the impeller shaft distal of the impeller body. The mounting portion can have a cylindrical member disposed on the impeller shaft and can include an enlarged distal portion having an inner diameter greater than the enlarged diameter at a distal end of the impeller shaft. Further, a re-sealable member can be disposed in the enlarged distal portion of the cylindrical member and can have a path through the re-sealable member through which a guidewire can be positioned.

Abstract: A septum for use in a catheter pump is provided herein. The septum includes a first elastomeric septa disc. The first elastomeric septa disc is punctured. The puncture forms an aperture in the first elastomeric septa disc. The aperture is passable by a guidewire.

Abstract: A catheter pump system includes a shaft assembly, an impeller coupled to a distal portion of the shaft assembly, and a motor assembly coupled to a proximal portion of the shaft assembly. The motor assembly is configured to drive the impeller via the shaft assembly. The motor assembly includes a rotor, a stator disposed radially outward of the rotor, and a rotor chamber disposed radially between the stator and the rotor. The rotor chamber at least partially encloses the rotor. The rotor chamber is at least partially filled with a lubricant to reduce a friction of the rotor during rotation thereof.

Abstract: An access closure device for closing an opening in tissue is provided. The access closure device may comprise a balloon delivery system and a sealant delivery system. The balloon delivery system may comprise a suture, a delivery shaft, an inflatable balloon, and a balloon segment releasably attached to the delivery shaft. The sealant delivery system may comprise a sealant delivery shaft, an ejection tube, and a snare wire configured to snare a suture of the delivery system.

Abstract: An apparatus and method for controlling inflation pressure, pressurization rate, and volumetric flow rate of a balloon during deployment of a stent or scaffold is disclosed.

Abstract: Embodiments are directed to radiopaque implantable structures (e.g., stents) formed of cobalt-based alloys that comprise cobalt, chromium and one or more platinum group metals, refractory metals, precious metals, or combinations thereof. Platinum group metals include platinum, palladium, ruthenium, rhodium, osmium, and iridium. Refractory metals include zirconium, niobium, rhodium, molybdenum, hafnium, tantalum, tungsten, rhenium, and precious metals include silver and gold. In one embodiment, the one or more included platinum group or refractory metals substitute at least partially for nickel, such that the alloy exhibits reduced nickel content, or is substantially nickel free. The stents exhibit improved radiopacity as compared to similar alloys including greater amounts of nickel.

Abstract: Bioabsorbable polymeric stent patterns with linking struts between rings that are designed to fail upon deployment of the stent are disclosed.

Abstract: Methods are disclosed including thermally processing a scaffold to increase the radial strength of the scaffold when the scaffold is deployed from a crimped state to a deployed state such as a nominal deployment diameter. The thermal processing may further maintain or increase the expansion capability of the scaffold when expanded beyond the nominal diameter.

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. A sheath is placed over the crimped scaffold after crimping to reduce recoil of the crimped polymer scaffold and maintain scaffold-balloon engagement relied on to hold the scaffold to the balloon when the scaffold is being delivered to a target in a body. The sheath is removed by a health professional either by removing the sheath directly or using a tube containing the catheter.

Abstract: A systems and method for reducing coating defects on a stent may involve a support apparatus comprising wire cage for carrying a stent. The support apparatus may have no structure that extends inside the stent. A support apparatus may include a plurality of wires that pass through the stent but do not pass through the midplane of the stent. A support apparatus may contact only the proximal ends of the stent. The method may involve keeping the stent in motion during a spray coating process to prevent the stent from having a point remain in continuous contact with a support apparatus.

Abstract: A method of loading a composition into a structural element of a stent, where the structural element is defined by a lumen and at least one opening to access the lumen. The composition may comprise a therapeutic agent, and wherein at a temperature of 30° C. and at one atmosphere, the composition may be in a solid state or semi-solid state.

Abstract: An implantable sent comprises a radiopaque marker that provides a structural connection between two parts made of a polymer substrate material. The two parts can be one bending element of one radially expandable ring and another bending element of an adjacent expandable ring. The two parts can be two bending elements of the same radially expandable ring. The radiopaque marker can be in the form of an entire radially expandable ring.

Abstract: The present invention provides an absorbable coating for an implantable device and the methods of making and using the same.

Abstract: The present disclosure teaches methods of controlling the release rate of agents from a polymeric matrix that include designing and creating a predetermined initial morphology (IM) profile in a polymeric matrix. The teachings indicate, inter alia, that control over the release rate of agents can provide for an improved control over the administration of agents as well as have an effect upon the mechanical integrity and absorption rate of the polymeric matrix.

Abstract: An implantable stent includes a plurality of rings. At least a distal end ring has an eased corner feature formed in the polymer substrate at a radially outward, distal-facing corner of the ring while relatively sharp corners of the polymer substrate are maintained in radially inward corners of the ring.

Abstract: A method for crimping a stent with a polymer coating in a humid environment is disclosed.

Abstract: The present invention provides an absorbable coating for an implantable device and the methods of making and using the same.

Abstract: A scaffold strut is shaped to improve hemocompatibility. The scaffold is made from a tube having variable wall thickness. Methods are disclosed for modifying the thickness of the tube in such a way as to achieve a reduced hemodynamic profile, but without significantly affecting strength properties in areas where stress concentrations exist when the scaffold is loaded.