Patents by Inventor Stephen Duguay

Stephen Duguay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SERUM-FREE MEDIA AND THEIR USES FOR CHONDROCYTE EXPANSION
    Publication number: 20130273010
    Abstract: The present invention provides defined serum-free cell culture media useful in culturing fibroblasts, especially articular chondrocytes, that avoid problems inherent in the use of serum-containing media. The defined media comprise platelet-derived growth factor (PDGF), chemically defined lipids, oncostatin M (OSM), interleukin-6 (IL-6), leukemia inhibitory factor (LIF), or combinations of these compounds. In another aspect, the present invention also provides tissue culture methods that comprise incubating chondrocytes in the defined serum-free media. The methods enhance attachment and proliferative expansion of chondrocytes seeded at low density while maintaining their redifferentiation potential.
    Type: Application
    Filed: April 16, 2013
    Publication date: October 17, 2013
    Applicant: GENZYME CORPORATION
    Inventors: Stephen DUGUAY, Barbara SEYMOUR
  • SERUM-FREE MEDIA AND THEIR USES FOR CHONDROCYTE EXPANSION
    Publication number: 20120213745
    Abstract: The present invention provides defined serum-free cell culture media useful in culturing fibroblasts, especially articular chondrocytes, that avoid problems inherent in the use of serum-containing media. The defined media comprise platelet-derived growth factor (PDGF), chemically defined lipids, oncostatin M (OSM), interleukin-6 (IL-6), leukemia inhibitory factor (LIF), or combinations of these compounds. In another aspect, the present invention also provides tissue culture methods that comprise incubating chondrocytes in the defined serum-free media. The methods enhance attachment and proliferative expansion of chondrocytes seeded at low density while maintaining their redifferentiation potential.
    Type: Application
    Filed: February 21, 2012
    Publication date: August 23, 2012
    Inventors: Stephen DUGUAY, Barbara SEYMOUR
  • SERUM-FREE MEDIA AND THEIR USES FOR CHONDROCYTE EXPANSION
    Publication number: 20070292949
    Abstract: The present invention provides defined serum-free cell culture media useful in culturing fibroblasts, especially articular chondrocytes, that avoid problems inherent in the use of serum-containing media. The defined media comprise platelet-derived growth factor (PDGF), chemically defined lipids, oncostatin M (OSM), interleukin-6 (IL-6), leukemia inhibitory factor (LIF), or combinations of these compounds. In another aspect, the present invention also provides tissue culture methods that comprise incubating chondrocytes in the defined serum-free media. The methods enhance attachment and proliferative expansion of chondrocytes seeded at low density while maintaining their redifferentiation potential.
    Type: Application
    Filed: June 15, 2007
    Publication date: December 20, 2007
    Applicant: Genzyme Corporation
    Inventors: Stephen Duguay, Barbara Seymour